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- W2044189596 abstract "The sample size required for determination of a given degree of difference between two therapies or modalities A and B being compared with each other, supposing that the sample sizes are equal, is given by Here Cα/2 is the upper α/2 percentile point of the standard normal distribution, C1−β is the abscissa cutting off the proportion 1−β in its upper tail and β in its lower tail; pA and pB are the probabilities of favorable response to A and B; if p̂A and p̂B are the corresponding measured proportions, then p = 12(p̂A + p̂B); and the Q's are 1 minus the p's. When it is desirable to use unequal size groups, the sample sizes n1" @default.
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- W2044189596 date "1977-01-01" @default.
- W2044189596 modified "2023-09-26" @default.
- W2044189596 title "Sample size determination for comparing two therapies taking both the α (type I or false positive) error and the β (type II or false negative) error into consideration" @default.
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