FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044202668> ?p ?o ?g. }

• W2044202668 endingPage "793" @default.
• W2044202668 startingPage "790" @default.
• W2044202668 abstract "Abstract Background and Aim: Acute exacerbation of chronic hepatitis B has to be distinguished from acute hepatitis, because treatment strategies differ between them. Methods: Mutations in the core promoter and precore region of hepatitis B virus (HBV) were determined in 36 patients with acute exacerbation of chronic hepatitis B, in whom alanine aminotransferase (ALT) increased above 500 IU/L, as well as the 36 patients with acute hepatitis. Results: Mutations in the core promoter (A1762T/G1764A) and precore region (G1896A) were more frequent in patients with acute exacerbation of chronic hepatitis than acute hepatitis (81% vs 19%; P < 0.0001 and 58% vs 6%; P < 0.0001, respectively). Of the 19 patients with mutations in both the core promoter and precore region, 17 (89%) had acute exacerbation of chronic hepatitis. In contrast, among the 32 patients with the wild‐type for both the core promoter and precore region, 29 (89%) developed acute hepatitis. By multivariate analysis, the double mutation in the core promoter was predictive of acute exacerbation in chronic hepatitis with the highest odds ratio at 26.4. Conclusions: In patients with hepatitis B having ALT levels >500 IU/L, mutations in the core promoter and precore region are useful in distinguishing acute exacerbation of chronic from acute HBV infection. Detection of these mutations would be useful for commencing prompt antiviral treatments on patients with acute exacerbation of chronic hepatitis for a better prognosis." @default.
• W2044202668 created "2016-06-24" @default.
• W2044202668 creator A5008132641 @default.
• W2044202668 creator A5033980070 @default.
• W2044202668 creator A5041366230 @default.
• W2044202668 creator A5044442302 @default.
• W2044202668 creator A5051843684 @default.
• W2044202668 creator A5060414282 @default.
• W2044202668 creator A5061344672 @default.
• W2044202668 creator A5064919937 @default.
• W2044202668 creator A5068900234 @default.
• W2044202668 creator A5074749813 @default.
• W2044202668 creator A5081194412 @default.
• W2044202668 creator A5081361453 @default.
• W2044202668 creator A5084495121 @default.
• W2044202668 creator A5088045861 @default.
• W2044202668 date "2008-04-08" @default.
• W2044202668 modified "2023-10-14" @default.
• W2044202668 title "Detection of HBV core promoter and precore mutations helps distinguish flares of chronic hepatitis from acute hepatitis B" @default.
• W2044202668 cites W1603193834 @default.
• W2044202668 cites W1793130233 @default.
• W2044202668 cites W1887371688 @default.
• W2044202668 cites W1940739348 @default.
• W2044202668 cites W1979866106 @default.
• W2044202668 cites W2018479084 @default.
• W2044202668 cites W2038155122 @default.
• W2044202668 cites W2047768999 @default.
• W2044202668 cites W2048370311 @default.
• W2044202668 cites W2049375257 @default.
• W2044202668 cites W2053259740 @default.
• W2044202668 cites W2058424177 @default.
• W2044202668 cites W2068920446 @default.
• W2044202668 cites W2070518669 @default.
• W2044202668 cites W2078148328 @default.
• W2044202668 cites W2081296213 @default.
• W2044202668 cites W2120128540 @default.
• W2044202668 cites W2128941790 @default.
• W2044202668 cites W2129923672 @default.
• W2044202668 cites W2131193659 @default.
• W2044202668 cites W2143216061 @default.
• W2044202668 cites W2154052746 @default.
• W2044202668 cites W2156015715 @default.
• W2044202668 cites W2166278066 @default.
• W2044202668 cites W2321075294 @default.
• W2044202668 cites W2327856202 @default.
• W2044202668 doi "https://doi.org/10.1111/j.1440-1746.2008.05391.x" @default.
• W2044202668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18410611" @default.
• W2044202668 hasPublicationYear "2008" @default.
• W2044202668 type Work @default.
• W2044202668 sameAs 2044202668 @default.
• W2044202668 citedByCount "22" @default.
• W2044202668 countsByYear W20442026682012 @default.
• W2044202668 countsByYear W20442026682013 @default.
• W2044202668 countsByYear W20442026682014 @default.
• W2044202668 countsByYear W20442026682015 @default.
• W2044202668 countsByYear W20442026682016 @default.
• W2044202668 countsByYear W20442026682018 @default.
• W2044202668 countsByYear W20442026682020 @default.
• W2044202668 countsByYear W20442026682021 @default.
• W2044202668 countsByYear W20442026682023 @default.
• W2044202668 crossrefType "journal-article" @default.
• W2044202668 hasAuthorship W2044202668A5008132641 @default.
• W2044202668 hasAuthorship W2044202668A5033980070 @default.
• W2044202668 hasAuthorship W2044202668A5041366230 @default.
• W2044202668 hasAuthorship W2044202668A5044442302 @default.
• W2044202668 hasAuthorship W2044202668A5051843684 @default.
• W2044202668 hasAuthorship W2044202668A5060414282 @default.
• W2044202668 hasAuthorship W2044202668A5061344672 @default.
• W2044202668 hasAuthorship W2044202668A5064919937 @default.
• W2044202668 hasAuthorship W2044202668A5068900234 @default.
• W2044202668 hasAuthorship W2044202668A5074749813 @default.
• W2044202668 hasAuthorship W2044202668A5081194412 @default.
• W2044202668 hasAuthorship W2044202668A5081361453 @default.
• W2044202668 hasAuthorship W2044202668A5084495121 @default.
• W2044202668 hasAuthorship W2044202668A5088045861 @default.
• W2044202668 hasConcept C126322002 @default.
• W2044202668 hasConcept C159047783 @default.
• W2044202668 hasConcept C203014093 @default.
• W2044202668 hasConcept C2522874641 @default.
• W2044202668 hasConcept C2776029263 @default.
• W2044202668 hasConcept C2777014857 @default.
• W2044202668 hasConcept C2777382497 @default.
• W2044202668 hasConcept C2780593183 @default.
• W2044202668 hasConcept C71924100 @default.
• W2044202668 hasConceptScore W2044202668C126322002 @default.
• W2044202668 hasConceptScore W2044202668C159047783 @default.
• W2044202668 hasConceptScore W2044202668C203014093 @default.
• W2044202668 hasConceptScore W2044202668C2522874641 @default.
• W2044202668 hasConceptScore W2044202668C2776029263 @default.
• W2044202668 hasConceptScore W2044202668C2777014857 @default.
• W2044202668 hasConceptScore W2044202668C2777382497 @default.
• W2044202668 hasConceptScore W2044202668C2780593183 @default.
• W2044202668 hasConceptScore W2044202668C71924100 @default.
• W2044202668 hasIssue "5" @default.
• W2044202668 hasLocation W20442026681 @default.
• W2044202668 hasLocation W20442026682 @default.
• W2044202668 hasOpenAccess W2044202668 @default.
• W2044202668 hasPrimaryLocation W20442026681 @default.

• next