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- W2044227734 abstract "Tissue samples from the cerebellum were obtained for electron microscopy from mice which were prenatally exposed to methyl mercury. Lysosomal accumulation was observed in both the Purkinje neurons and granule cells. Osmiophilic lipoid material was evident within these lysosomes. Giant-sized lysosomes were also found occasionally. Irregular tubular structures resembling smooth endoplasmic reticulum were also found within many neurites. Some of these tubular structures appeared to be hypertrophied and contained some electron-opaque materials. Segmental incomplete myelination and abnormal synaptic terminals were also observed in the tissue samples. Such defects may contribute to the behavioral deviation and mental deficiencies of these animals." @default.
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- W2044227734 date "1977-04-01" @default.
- W2044227734 modified "2023-10-18" @default.
- W2044227734 title "Ultrastructural study of the latent effects of methyl mercury on the nervous system after prenatal exposure" @default.
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- W2044227734 doi "https://doi.org/10.1016/0013-9351(77)90095-0" @default.
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