Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044230858> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2044230858 endingPage "1313" @default.
- W2044230858 startingPage "1307" @default.
- W2044230858 abstract "The mitochondrial respiratory chain (MRC) supplies the majority of the energy requirements of most eucaryotic cells. A null mutation in the Caenorhabditis elegans nuo-1 gene encoding a subunit of complex I (NADH-ubiquinone oxidoreductase) is lethal, leading to a developmental arrest at the third larval stage. To identify the tissues that regulate development in response to mitochondrial dysfunction, we restored nuo-1 expression with tissue-specific promoters. Only expression of nuo-1 ubiquitously or in the nervous system supported development to the adult stage. Pharyngeal expression of nuo-1 allowed development to proceed to the fourth larval stage. Expression of nuo-1 in the body muscles or in the germline had no effect. Furthermore, only ubiquitous or nervous system expression of nuo-1 allowed exit from the dauer state. Our results indicate that MRC function in the nervous system is needed to send and receive signals that control larval development and exit from dauer." @default.
- W2044230858 created "2016-06-24" @default.
- W2044230858 creator A5023747476 @default.
- W2044230858 creator A5059902467 @default.
- W2044230858 date "2004-07-01" @default.
- W2044230858 modified "2023-09-27" @default.
- W2044230858 title "Caenorhabditis elegans development requires mitochondrial function in the nervous system" @default.
- W2044230858 cites W1581412826 @default.
- W2044230858 cites W1587592813 @default.
- W2044230858 cites W1619158228 @default.
- W2044230858 cites W1911220294 @default.
- W2044230858 cites W1968197570 @default.
- W2044230858 cites W1971374859 @default.
- W2044230858 cites W1973722927 @default.
- W2044230858 cites W1978587926 @default.
- W2044230858 cites W1982164848 @default.
- W2044230858 cites W1997554636 @default.
- W2044230858 cites W2001908075 @default.
- W2044230858 cites W2012003686 @default.
- W2044230858 cites W2015702651 @default.
- W2044230858 cites W2020665485 @default.
- W2044230858 cites W2048967691 @default.
- W2044230858 cites W2054757732 @default.
- W2044230858 cites W2063098376 @default.
- W2044230858 cites W2064352437 @default.
- W2044230858 cites W2066660409 @default.
- W2044230858 cites W2068568687 @default.
- W2044230858 cites W2072969519 @default.
- W2044230858 cites W2083844348 @default.
- W2044230858 cites W2091613063 @default.
- W2044230858 cites W2106742994 @default.
- W2044230858 cites W2112510720 @default.
- W2044230858 cites W2124307065 @default.
- W2044230858 cites W2124307323 @default.
- W2044230858 cites W2155265427 @default.
- W2044230858 cites W2235504444 @default.
- W2044230858 cites W4295847395 @default.
- W2044230858 doi "https://doi.org/10.1016/j.bbrc.2004.05.108" @default.
- W2044230858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15194510" @default.
- W2044230858 hasPublicationYear "2004" @default.
- W2044230858 type Work @default.
- W2044230858 sameAs 2044230858 @default.
- W2044230858 citedByCount "9" @default.
- W2044230858 countsByYear W20442308582013 @default.
- W2044230858 countsByYear W20442308582016 @default.
- W2044230858 countsByYear W20442308582017 @default.
- W2044230858 countsByYear W20442308582020 @default.
- W2044230858 countsByYear W20442308582022 @default.
- W2044230858 crossrefType "journal-article" @default.
- W2044230858 hasAuthorship W2044230858A5023747476 @default.
- W2044230858 hasAuthorship W2044230858A5059902467 @default.
- W2044230858 hasConcept C104317684 @default.
- W2044230858 hasConcept C14036430 @default.
- W2044230858 hasConcept C169760540 @default.
- W2044230858 hasConcept C24586158 @default.
- W2044230858 hasConcept C2778944004 @default.
- W2044230858 hasConcept C28859421 @default.
- W2044230858 hasConcept C3020377403 @default.
- W2044230858 hasConcept C3020761558 @default.
- W2044230858 hasConcept C54355233 @default.
- W2044230858 hasConcept C545706735 @default.
- W2044230858 hasConcept C86803240 @default.
- W2044230858 hasConcept C95444343 @default.
- W2044230858 hasConceptScore W2044230858C104317684 @default.
- W2044230858 hasConceptScore W2044230858C14036430 @default.
- W2044230858 hasConceptScore W2044230858C169760540 @default.
- W2044230858 hasConceptScore W2044230858C24586158 @default.
- W2044230858 hasConceptScore W2044230858C2778944004 @default.
- W2044230858 hasConceptScore W2044230858C28859421 @default.
- W2044230858 hasConceptScore W2044230858C3020377403 @default.
- W2044230858 hasConceptScore W2044230858C3020761558 @default.
- W2044230858 hasConceptScore W2044230858C54355233 @default.
- W2044230858 hasConceptScore W2044230858C545706735 @default.
- W2044230858 hasConceptScore W2044230858C86803240 @default.
- W2044230858 hasConceptScore W2044230858C95444343 @default.
- W2044230858 hasIssue "4" @default.
- W2044230858 hasLocation W20442308581 @default.
- W2044230858 hasLocation W20442308582 @default.
- W2044230858 hasOpenAccess W2044230858 @default.
- W2044230858 hasPrimaryLocation W20442308581 @default.
- W2044230858 hasRelatedWork W1981938774 @default.
- W2044230858 hasRelatedWork W2004973214 @default.
- W2044230858 hasRelatedWork W2076407597 @default.
- W2044230858 hasRelatedWork W2080999476 @default.
- W2044230858 hasRelatedWork W2085962754 @default.
- W2044230858 hasRelatedWork W2278153843 @default.
- W2044230858 hasRelatedWork W36333329 @default.
- W2044230858 hasRelatedWork W4292218865 @default.
- W2044230858 hasRelatedWork W43799683 @default.
- W2044230858 hasRelatedWork W2120071225 @default.
- W2044230858 hasVolume "319" @default.
- W2044230858 isParatext "false" @default.
- W2044230858 isRetracted "false" @default.
- W2044230858 magId "2044230858" @default.
- W2044230858 workType "article" @default.