FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044267951> ?p ?o ?g. }

• W2044267951 endingPage "379" @default.
• W2044267951 startingPage "368" @default.
• W2044267951 abstract "The effect of thyroid status on QO2, QO2 (t) and NaK-ATPase activity was examined in rat skeletal muscle. QO2(t) (i.e. Na+-transport-dependent respiration) was estimated with ouabain or Na+-free media supplemented with K+. In contrast to the effects of ouabain on ion composition, intracellular K+ was maintained at about 125 meq/liter, and intracellular Na+ was almost nil in the Na+-free media. The estimates of QO2(t) were independent of the considerable differences in tissue ion concentrations. The increase in QO2(t) account for 47% of the increase in QO2 in the transition from the hypothyroid to the euthyroid state and 84% of the increase in the transition from the euthyroid to the hyperthyroid state. Surgical thyroidectomy lowered NaK-ATPase activity of the microsomal fraction (expressed per milligram protein) 32%; injections of triodothyronine (T3) increased this activity 75% in initially hypothyroid rats and 26% in initially euthyroid rats. Thyroidectomy was attended by significant falls in serum Ca and Pi concentrations. Administration of T3 resulted in further declines in serum Ca and marked increases in serum Ps concentrations. Similar effects were seen in 131I-treated rats, but the magnitude of the declines in serum Ca were less. The effects of T3 on QO2, QO2(t), and NaK-ATPase activity of skeletal muscle were indistinguishable in the 131I-ablated and surgically thyroidectomized rats. In thyroidectomized or euthyroid rats given repeated doses of T3, QO2(t) and NaA-ATPase activity increased proportionately. In thyroidectomized rats injected with single doses of T3, either 10, 50, or 250 mug/100 g body wt, QO2(t) increased linearly with NaK-ATPase activity. The kinetics of the NaK-ATPase activity was assessed with an ATP-generating system. T3 elicited a significant increase in Vmax with no change in Km for ATP." @default.
• W2044267951 created "2016-06-24" @default.
• W2044267951 creator A5007508591 @default.
• W2044267951 creator A5068028039 @default.
• W2044267951 creator A5084978531 @default.
• W2044267951 date "1976-02-01" @default.
• W2044267951 modified "2023-09-26" @default.
• W2044267951 title "Thyroid thermogenesis. Relationships between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in rat skeletal muscle." @default.
• W2044267951 cites W109830437 @default.
• W2044267951 cites W1775749144 @default.
• W2044267951 cites W1897079130 @default.
• W2044267951 cites W1970464340 @default.
• W2044267951 cites W1972169331 @default.
• W2044267951 cites W1973035812 @default.
• W2044267951 cites W1981158796 @default.
• W2044267951 cites W1988120022 @default.
• W2044267951 cites W1988747936 @default.
• W2044267951 cites W1988758382 @default.
• W2044267951 cites W2014966624 @default.
• W2044267951 cites W2024216618 @default.
• W2044267951 cites W2025440417 @default.
• W2044267951 cites W2032740256 @default.
• W2044267951 cites W2041247039 @default.
• W2044267951 cites W2051166466 @default.
• W2044267951 cites W2060326207 @default.
• W2044267951 cites W2065979129 @default.
• W2044267951 cites W2072909058 @default.
• W2044267951 cites W2081179138 @default.
• W2044267951 cites W2083260212 @default.
• W2044267951 cites W2085722214 @default.
• W2044267951 cites W2103592242 @default.
• W2044267951 cites W2158264015 @default.
• W2044267951 cites W2158976414 @default.
• W2044267951 cites W2197278359 @default.
• W2044267951 cites W2205753780 @default.
• W2044267951 cites W2242751894 @default.
• W2044267951 cites W2262850450 @default.
• W2044267951 cites W2314970555 @default.
• W2044267951 cites W2327828625 @default.
• W2044267951 cites W2410026824 @default.
• W2044267951 cites W2413058670 @default.
• W2044267951 cites W2468677958 @default.
• W2044267951 cites W2753054337 @default.
• W2044267951 doi "https://doi.org/10.1172/jci108288" @default.
• W2044267951 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/436661" @default.
• W2044267951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/130385" @default.
• W2044267951 hasPublicationYear "1976" @default.
• W2044267951 type Work @default.
• W2044267951 sameAs 2044267951 @default.
• W2044267951 citedByCount "159" @default.
• W2044267951 countsByYear W20442679512012 @default.
• W2044267951 countsByYear W20442679512013 @default.
• W2044267951 countsByYear W20442679512014 @default.
• W2044267951 countsByYear W20442679512016 @default.
• W2044267951 countsByYear W20442679512017 @default.
• W2044267951 countsByYear W20442679512021 @default.
• W2044267951 crossrefType "journal-article" @default.
• W2044267951 hasAuthorship W2044267951A5007508591 @default.
• W2044267951 hasAuthorship W2044267951A5068028039 @default.
• W2044267951 hasAuthorship W2044267951A5084978531 @default.
• W2044267951 hasBestOaLocation W20442679511 @default.
• W2044267951 hasConcept C126322002 @default.
• W2044267951 hasConcept C134018914 @default.
• W2044267951 hasConcept C151279926 @default.
• W2044267951 hasConcept C178790620 @default.
• W2044267951 hasConcept C181199279 @default.
• W2044267951 hasConcept C182215343 @default.
• W2044267951 hasConcept C185592680 @default.
• W2044267951 hasConcept C23265538 @default.
• W2044267951 hasConcept C2777074255 @default.
• W2044267951 hasConcept C2777195454 @default.
• W2044267951 hasConcept C2778288131 @default.
• W2044267951 hasConcept C2779133857 @default.
• W2044267951 hasConcept C2779959927 @default.
• W2044267951 hasConcept C511355011 @default.
• W2044267951 hasConcept C526584372 @default.
• W2044267951 hasConcept C537181965 @default.
• W2044267951 hasConcept C55493867 @default.
• W2044267951 hasConcept C59822182 @default.
• W2044267951 hasConcept C71924100 @default.
• W2044267951 hasConcept C86803240 @default.
• W2044267951 hasConceptScore W2044267951C126322002 @default.
• W2044267951 hasConceptScore W2044267951C134018914 @default.
• W2044267951 hasConceptScore W2044267951C151279926 @default.
• W2044267951 hasConceptScore W2044267951C178790620 @default.
• W2044267951 hasConceptScore W2044267951C181199279 @default.
• W2044267951 hasConceptScore W2044267951C182215343 @default.
• W2044267951 hasConceptScore W2044267951C185592680 @default.
• W2044267951 hasConceptScore W2044267951C23265538 @default.
• W2044267951 hasConceptScore W2044267951C2777074255 @default.
• W2044267951 hasConceptScore W2044267951C2777195454 @default.
• W2044267951 hasConceptScore W2044267951C2778288131 @default.
• W2044267951 hasConceptScore W2044267951C2779133857 @default.
• W2044267951 hasConceptScore W2044267951C2779959927 @default.
• W2044267951 hasConceptScore W2044267951C511355011 @default.
• W2044267951 hasConceptScore W2044267951C526584372 @default.
• W2044267951 hasConceptScore W2044267951C537181965 @default.
• W2044267951 hasConceptScore W2044267951C55493867 @default.

• next