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• W2044300551 abstract "CA: A Cancer Journal for CliniciansVolume 37, Issue 4 p. 246-251 FeatureFree Access Carcinoma of the male breast and klinefelter's syndrome: Is there an association? Douglas B. Evans M.D., Douglas B. Evans M.D. Resident in General Surgery at Dartmouth-Hitchcock Medical Center in Hanover, New HampshireSearch for more papers by this authorRobert W. Crichlow M.D., Robert W. Crichlow M.D. Chairman of, and William and Bessie Allyn Professor in, the Department of Surgery at Dartmouth-Hitchcock Medical Center in Hanover, New HampshireSearch for more papers by this author Douglas B. Evans M.D., Douglas B. Evans M.D. Resident in General Surgery at Dartmouth-Hitchcock Medical Center in Hanover, New HampshireSearch for more papers by this authorRobert W. Crichlow M.D., Robert W. Crichlow M.D. Chairman of, and William and Bessie Allyn Professor in, the Department of Surgery at Dartmouth-Hitchcock Medical Center in Hanover, New HampshireSearch for more papers by this author First published: July/August 1987 https://doi.org/10.3322/canjclin.37.4.246Citations: 73AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Klinefelter HF Jr, Reifenstein EC Jr, Albright F: Syndrome characterized by gynecomastia aspermatogenesis without A-leydigism, and increased excretion of follicle-stimulating hormone. J Clin Endocrinol 2: 615– 627, 1942. 2 Jacobs PA, Strong JA: A case of human intersexuality having a possible XXY sex-determining mechanism. Nature 183: 302– 303, 1959. 3 Bauer DD, Erickson RL: Male breast cancer: Klinefelter syndrome with prostatic, adrenal and mammary tumors. Northwest Med 54: 472– 476, 1955. 4 Jackson AW, Muldal S, Ockey CH, et al: Carcinoma of male breast in association with the, Klinefelter syndrome. Brit Med J 5429: 223– 225, 1965. 5 Harnden DG, MacLean N, Langlands AO: Carcinoma of the breast and Klinefelter's syndrome. J Med Genet 8: 460– 461, 1971. 6 Jacobs PA: The incidence and etiology of sex chromosome abnormalities in man. Birth Defects 15: 3– 14, 1979. 7 Salbenblatt JA, Bender BG, Puck MH, et al: Pituitary-gonadal function in Klinefelter syndrome before and during puberty. Pediatr Res 19: 82– 86, 1985. 8 Dao TL, Morreal C, Nemoto T: Urinary estrogen excretion in men with breast cancer. N Engl J Med 289: 138– 140, 1973. 9 Crichlow RW, Evans DB: Cancer in the male breast, in IM Ariel, JB Cleary (eds): Breast Cancer: Diagnosis and Treatment. New York, McGraw-Hill, 1987, pp 516– 528. 10 Simpson JL, Photopulos G: The relationship of neoplasia to disorders of abnormal sexual differentiation. Birth Defects 12: 15– 50, 1976. 11 Dodge OG, Jackson AW, Muldal S: Breast cancer and interstitial-cell tumor in a patient with Klinefelter's syndrome. Cancer 24: 1027– 1032, 1969. 12 Gustavson KH, Gamstorp I, Meurling S: Bilateral teratoma of testis in two brothers with 47, XXY Klinefelter's syndrome. Clin Genet 8: 5– 10, 1975. 13 Robson MC, Santiago Q, Huang TW: Bilateral carcinoma of the breast in a patient with Klinefelter's syndrome. J Clin Endoct 28: 897– 902, 1968. 14 Brown PW, Terz JJ: Breast carcinoma associated with Klinefelter syndrome: A case report. J Surg Oncol 10: 413– 415, 1978. 15 Davis JC, Wade AP: Discordant identical twins: III. Klinefelter's syndrome discordant for carcinoma of the breast. Practitioner 209: 380– 383, 1972. 16 Coley GM, Otis RD, Clark WE: Multiple primary tumors including bilateral breast cancers in a man with Klinefelter's syndrome. Cancer 27: 1476– 1481, 1971. 17 Griesemer DA: Clinical conferences at the Johns Hopkins Hospital: Klinefelter syndrome and breast cancer. Johns Hopkins Med J 138: 102– 108, 1976. 18 Mies R, Fischer H. Pfeiff B, et al: Klinefelter's syndrome and breast cancer. Andrologia 14: 317– 321, 1982. 19 Lynch HT, Kaplan AR, Lynch JF: Klinefelter syndrome and cancer: A family study, JAMA 229: 809– 811, 1974. 20 Giammarini A, Rocchi M, Zennaro W, et al: XX male with breast cancer. Clin Genet 18: 103– 108, 1980. 21 Moshakis V, Fordyce MJ, Griffiths JD: Klinefelter's syndrome associated with breast carcinoma and Paget's disease of the nipple. Clin Oncol 9: 257– 261, 1983. 22 Carlson HE: Gynecomastia. N Engl J Med 303: 795– 799, 1980. 23 Harnden DG: Chromosome abnormalities and predisposition towards cancer. Proc R Soc Med 69: 41– 43, 1976. 24 Murkerjee D, Bowen J, Anderson DE: Simian papovavirus 40 transformation of cells from cancer patient with XY/XXY mosaic Klinefelter's syndrome. Cancer Res 30: 1769– 1772, 1970. 25 Scheike O: Male breast cancer. Acta Pathol Microbiol Scand[A] Suppl 251: 13– 35, 1975. 26 van Geel AN, van Slooten EA, Mavrunac M, et al: A retrospective study of male breast cancer in Holland. Br J Surg 72: 724– 727, 1985. 27 Cuenca CR, Becker KL: Klinefelter's syndrome and cancer of the breast. Arch Intern Med 121: 159– 162, 1968. 28 Scheike O, Visfeldt J, Petersen B: Male breast cancer: III. Breast carcinoma in association with the Klinefelter syndrome. Acta Pathol Microbiol Scand[A] 81: 352– 358, 1973. 29 Harris JR, Hellman S, Canellos GP, et al: Cancer of the breast, in VT DeVita, S Hellman, SA Rosenberg (eds): Cancer: Principles and Practice of Oncology, 2nd edition. Philadelphia, JB Lippincott, 1985, pp 1119– 1177. 30 Sanchez AG, Villanueva AG, Redondo C: Lobular carcinoma of the breast in a patient with Klinefelter's syndrome. Cancer 57: 118I- 1183, 1986. 31 Kirubakaran V, Mayfield D: Klinefelter's syndrome, schizophrenia, and breast cancer. Am J Psychiatry 140: 271, 1983. 32 Ellison HS, Scheuer SA, Eichner ER: Metastatic breast carcinoma with positive estrogen and progesterone receptors in a man with Klinefelter's syndrome. South Med J 73: 1393– 1396, 1980. 33 Roswit B, Edlis H: Carcinoma of the male breast: A thirty year experience and literature review. Int J Radiation Oncology Biol Phys 4: 711– 716, 1978. 34 Jefferys DB, Efthimiou J: Carcinoma of the male breast and oestrogen metabolism. Br Med J 1: 1697. 1978. 35 Keller AZ: Demographic, clinical and survivorship characteristics of males with primary cancer of the breast. Amer J Epidem 85: 183– 199. 1967. 36 Jackson AW, Mulda S, Ockey CH, et al: Carcinoma of male breast in association with the Klinefelter syndrome. Brit Med J 5429: 223– 225, 1965. 37 Gupta RL: Carcinoma of the breast in a case of Klinefelter syndrome. Indian J Cancer 3: 184– 189, 1966. Citing Literature Volume37, Issue4July/August 1987Pages 246-251 ReferencesRelatedInformation" @default.
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