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- W2044318488 abstract "Abstract Ten azeto[2,1-d][1,5]benzothiazepinone derivatives 6a–j were synthesized starting from 4-acetyl-2-phenyl-1,2,3-triazole 1. First, condensation of 1 with various aldehydes 2a–e afforded α,β-unsaturated carbonyl compounds 3a–e, which subsequently underwent cyclization with o-aminothiophenol to yield the corresponding 2,4-disubstituted-1,5-benzothiazepines 4a–e. Treatment of 4a–e with chloroacetyl chloride 5a or phenoxyacetyl chloride 5b by [2+2] cycloaddition reaction gave the title compounds 6a–j. The assignment of the structures of 6a–j was made by 1H NMR, MS, and elemental analyses. Keywords: 4-Acetyl-2-phenyl-1,2,3-triazolebenzothiazepine[2+2] cycloaddition β-lactam" @default.
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- W2044318488 date "2010-10-28" @default.
- W2044318488 modified "2023-10-09" @default.
- W2044318488 title "Synthesis of Some Prospective Bioactive Azeto[2,1-d][1,5]benzothiazepinones" @default.
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- W2044318488 doi "https://doi.org/10.1080/10426501003657527" @default.
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