FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044334871> ?p ?o ?g. }

• W2044334871 abstract "HIV-1 drug resistance has the potential to seriously compromise the effectiveness and impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to expand, individuals on ART should be closely monitored for the emergence of drug resistance. Surveillance of transmitted drug resistance to track transmission of viral strains already resistant to ART is also critical. Unfortunately, drug resistance testing is still not readily accessible in resource limited settings, because genotyping is expensive and requires sophisticated laboratory and data management infrastructure. An open access genotypic drug resistance monitoring method to manage individuals and assess transmitted drug resistance is described. The method uses free open source software for the interpretation of drug resistance patterns and the generation of individual patient reports. The genotyping protocol has an amplification rate of greater than 95% for plasma samples with a viral load >1,000 HIV-1 RNA copies/ml. The sensitivity decreases significantly for viral loads <1,000 HIV-1 RNA copies/ml. The method described here was validated against a method of HIV-1 drug resistance testing approved by the United States Food and Drug Administration (FDA), the Viroseq genotyping method. Limitations of the method described here include the fact that it is not automated and that it also failed to amplify the circulating recombinant form CRF02_AG from a validation panel of samples, although it amplified subtypes A and B from the same panel." @default.
• W2044334871 created "2016-06-24" @default.
• W2044334871 creator A5006120211 @default.
• W2044334871 creator A5012288385 @default.
• W2044334871 creator A5031077871 @default.
• W2044334871 creator A5042232387 @default.
• W2044334871 creator A5057190505 @default.
• W2044334871 creator A5067263531 @default.
• W2044334871 creator A5070597258 @default.
• W2044334871 creator A5071612716 @default.
• W2044334871 creator A5074129263 @default.
• W2044334871 creator A5079230150 @default.
• W2044334871 creator A5081844950 @default.
• W2044334871 creator A5086687566 @default.
• W2044334871 date "2014-03-30" @default.
• W2044334871 modified "2023-10-16" @default.
• W2044334871 title "An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings" @default.
• W2044334871 cites W118723068 @default.
• W2044334871 cites W128874805 @default.
• W2044334871 cites W1509684056 @default.
• W2044334871 cites W1604139172 @default.
• W2044334871 cites W179285875 @default.
• W2044334871 cites W1872355166 @default.
• W2044334871 cites W1969623552 @default.
• W2044334871 cites W1982920562 @default.
• W2044334871 cites W1984770848 @default.
• W2044334871 cites W2001977485 @default.
• W2044334871 cites W2022950995 @default.
• W2044334871 cites W2029531333 @default.
• W2044334871 cites W2030315518 @default.
• W2044334871 cites W2036408211 @default.
• W2044334871 cites W2056539403 @default.
• W2044334871 cites W2069494783 @default.
• W2044334871 cites W2076346424 @default.
• W2044334871 cites W2079209638 @default.
• W2044334871 cites W2081614557 @default.
• W2044334871 cites W2086462809 @default.
• W2044334871 cites W2090564884 @default.
• W2044334871 cites W2112273750 @default.
• W2044334871 cites W2117261241 @default.
• W2044334871 cites W2119918172 @default.
• W2044334871 cites W2120110886 @default.
• W2044334871 cites W2120637537 @default.
• W2044334871 cites W2121717451 @default.
• W2044334871 cites W2124995497 @default.
• W2044334871 cites W2126887879 @default.
• W2044334871 cites W2127832030 @default.
• W2044334871 cites W2128229768 @default.
• W2044334871 cites W2129810760 @default.
• W2044334871 cites W2152896082 @default.
• W2044334871 cites W2154547850 @default.
• W2044334871 cites W2168797913 @default.
• W2044334871 cites W2169235930 @default.
• W2044334871 cites W2183940924 @default.
• W2044334871 cites W2337143807 @default.
• W2044334871 cites W2404812630 @default.
• W2044334871 doi "https://doi.org/10.3791/51242" @default.
• W2044334871 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4024245" @default.
• W2044334871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24747156" @default.
• W2044334871 hasPublicationYear "2014" @default.
• W2044334871 type Work @default.
• W2044334871 sameAs 2044334871 @default.
• W2044334871 citedByCount "27" @default.
• W2044334871 countsByYear W20443348712013 @default.
• W2044334871 countsByYear W20443348712014 @default.
• W2044334871 countsByYear W20443348712015 @default.
• W2044334871 countsByYear W20443348712016 @default.
• W2044334871 countsByYear W20443348712017 @default.
• W2044334871 countsByYear W20443348712018 @default.
• W2044334871 countsByYear W20443348712019 @default.
• W2044334871 countsByYear W20443348712020 @default.
• W2044334871 countsByYear W20443348712021 @default.
• W2044334871 countsByYear W20443348712022 @default.
• W2044334871 countsByYear W20443348712023 @default.
• W2044334871 crossrefType "journal-article" @default.
• W2044334871 hasAuthorship W2044334871A5006120211 @default.
• W2044334871 hasAuthorship W2044334871A5012288385 @default.
• W2044334871 hasAuthorship W2044334871A5031077871 @default.
• W2044334871 hasAuthorship W2044334871A5042232387 @default.
• W2044334871 hasAuthorship W2044334871A5057190505 @default.
• W2044334871 hasAuthorship W2044334871A5067263531 @default.
• W2044334871 hasAuthorship W2044334871A5070597258 @default.
• W2044334871 hasAuthorship W2044334871A5071612716 @default.
• W2044334871 hasAuthorship W2044334871A5074129263 @default.
• W2044334871 hasAuthorship W2044334871A5079230150 @default.
• W2044334871 hasAuthorship W2044334871A5081844950 @default.
• W2044334871 hasAuthorship W2044334871A5086687566 @default.
• W2044334871 hasBestOaLocation W20443348712 @default.
• W2044334871 hasConcept C104317684 @default.
• W2044334871 hasConcept C114851261 @default.
• W2044334871 hasConcept C135763542 @default.
• W2044334871 hasConcept C142462285 @default.
• W2044334871 hasConcept C159047783 @default.
• W2044334871 hasConcept C2778451633 @default.
• W2044334871 hasConcept C2780035454 @default.
• W2044334871 hasConcept C2993143319 @default.
• W2044334871 hasConcept C3013748606 @default.
• W2044334871 hasConcept C31467283 @default.
• W2044334871 hasConcept C41008148 @default.
• W2044334871 hasConcept C54355233 @default.

• next