Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044337579> ?p ?o ?g. }
- W2044337579 endingPage "929" @default.
- W2044337579 startingPage "917" @default.
- W2044337579 abstract "Decreased arsenate [As(V)] uptake is the major mechanism of naturally selected As(V) hypertolerance in plants. However, As(V)-hypertolerant ecotypes also show enhanced rates of phytochelatin (PC) accumulation, suggesting that improved sequestration might additionally contribute to the hypertolerance phenotype. Here, we show that enhanced PC-based sequestration in As(V)-hypertolerant Holcus lanatus is not due to an enhanced capacity for PC synthesis as such, but to increased As(V) reductase activity. Vacuolar transport of arsenite-thiol complexes was equal in both ecotypes. Based on homology with the yeast As(V) reductase, Acr2p, we identified a Cdc25-like plant candidate, HlAsr, and confirmed the As(V) reductase activity of both HlAsr and the homologous protein from Arabidopsis thaliana. The gene appeared to be As(V)-inducible and its expression was enhanced in the As(V)-hypertolerant H. lanatus ecotype, compared with the non-tolerant ecotype. Homologous ectopic overexpression of the AtASR cDNA in A. thaliana produced a dual phenotype. It improved tolerance to mildly toxic levels of As(V) exposure, but caused hypersensitivity to more toxic levels. Arabidopsis asr T-DNA mutants showed increased As(V) sensitivity at low exposure levels and enhanced arsenic retention in the root. It is argued that, next to decreased uptake, enhanced expression of HlASR might act as an additional determinant of As(V) hypertolerance and As transport in H. lanatus." @default.
- W2044337579 created "2016-06-24" @default.
- W2044337579 creator A5022587542 @default.
- W2044337579 creator A5036841683 @default.
- W2044337579 creator A5037039399 @default.
- W2044337579 creator A5054638480 @default.
- W2044337579 creator A5069352329 @default.
- W2044337579 date "2006-02-09" @default.
- W2044337579 modified "2023-10-15" @default.
- W2044337579 title "Enhanced arsenate reduction by a CDC25-like tyrosine phosphatase explains increased phytochelatin accumulation in arsenate-tolerant<i>Holcus lanatus</i>" @default.
- W2044337579 cites W1505328953 @default.
- W2044337579 cites W1560709946 @default.
- W2044337579 cites W1573664132 @default.
- W2044337579 cites W1935326600 @default.
- W2044337579 cites W1963602884 @default.
- W2044337579 cites W1967245994 @default.
- W2044337579 cites W1971206002 @default.
- W2044337579 cites W1981671259 @default.
- W2044337579 cites W1982383014 @default.
- W2044337579 cites W1989511088 @default.
- W2044337579 cites W1989720557 @default.
- W2044337579 cites W1989897632 @default.
- W2044337579 cites W1992089306 @default.
- W2044337579 cites W1992214347 @default.
- W2044337579 cites W1996198430 @default.
- W2044337579 cites W1998064335 @default.
- W2044337579 cites W1999165043 @default.
- W2044337579 cites W1999475620 @default.
- W2044337579 cites W2001847973 @default.
- W2044337579 cites W2005478615 @default.
- W2044337579 cites W2007394339 @default.
- W2044337579 cites W2008065134 @default.
- W2044337579 cites W2011783995 @default.
- W2044337579 cites W2018066181 @default.
- W2044337579 cites W2019348713 @default.
- W2044337579 cites W2023254006 @default.
- W2044337579 cites W2025327528 @default.
- W2044337579 cites W2028997445 @default.
- W2044337579 cites W2031711023 @default.
- W2044337579 cites W2032648454 @default.
- W2044337579 cites W2035026458 @default.
- W2044337579 cites W2035172318 @default.
- W2044337579 cites W2036336537 @default.
- W2044337579 cites W2059388121 @default.
- W2044337579 cites W2065926691 @default.
- W2044337579 cites W2066330235 @default.
- W2044337579 cites W2071428728 @default.
- W2044337579 cites W2075435443 @default.
- W2044337579 cites W2077074822 @default.
- W2044337579 cites W2082582931 @default.
- W2044337579 cites W2091297151 @default.
- W2044337579 cites W2098113933 @default.
- W2044337579 cites W2104057321 @default.
- W2044337579 cites W2109773487 @default.
- W2044337579 cites W2114264507 @default.
- W2044337579 cites W2116122104 @default.
- W2044337579 cites W2119788856 @default.
- W2044337579 cites W2127347907 @default.
- W2044337579 cites W2131588069 @default.
- W2044337579 cites W2133081259 @default.
- W2044337579 cites W2137876675 @default.
- W2044337579 cites W2143445757 @default.
- W2044337579 cites W2146520872 @default.
- W2044337579 cites W2154842664 @default.
- W2044337579 cites W2157856007 @default.
- W2044337579 cites W2160008637 @default.
- W2044337579 cites W2161386800 @default.
- W2044337579 cites W2162677202 @default.
- W2044337579 cites W2171134786 @default.
- W2044337579 cites W2502746008 @default.
- W2044337579 cites W302267139 @default.
- W2044337579 doi "https://doi.org/10.1111/j.1365-313x.2005.02651.x" @default.
- W2044337579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16507083" @default.
- W2044337579 hasPublicationYear "2006" @default.
- W2044337579 type Work @default.
- W2044337579 sameAs 2044337579 @default.
- W2044337579 citedByCount "246" @default.
- W2044337579 countsByYear W20443375792012 @default.
- W2044337579 countsByYear W20443375792013 @default.
- W2044337579 countsByYear W20443375792014 @default.
- W2044337579 countsByYear W20443375792015 @default.
- W2044337579 countsByYear W20443375792016 @default.
- W2044337579 countsByYear W20443375792017 @default.
- W2044337579 countsByYear W20443375792018 @default.
- W2044337579 countsByYear W20443375792019 @default.
- W2044337579 countsByYear W20443375792020 @default.
- W2044337579 countsByYear W20443375792021 @default.
- W2044337579 countsByYear W20443375792022 @default.
- W2044337579 countsByYear W20443375792023 @default.
- W2044337579 crossrefType "journal-article" @default.
- W2044337579 hasAuthorship W2044337579A5022587542 @default.
- W2044337579 hasAuthorship W2044337579A5036841683 @default.
- W2044337579 hasAuthorship W2044337579A5037039399 @default.
- W2044337579 hasAuthorship W2044337579A5054638480 @default.
- W2044337579 hasAuthorship W2044337579A5069352329 @default.
- W2044337579 hasBestOaLocation W20443375791 @default.
- W2044337579 hasConcept C104317684 @default.
- W2044337579 hasConcept C10860467 @default.