Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044339393> ?p ?o ?g. }
- W2044339393 endingPage "633" @default.
- W2044339393 startingPage "625" @default.
- W2044339393 abstract "The pathogenesis of “spontaneous angina” was investigated in five patients with so-called variant angina. Electrocardiographic monitoring demonstrated that several ischemic episodes were asymptomatic. Right and left ventricular pressure monitoring during 26 episodes of ST-segment elevation and two of ST-segment depression demonstrated that no hemodynamic change indicative of increased myocardial demands ever preceded the episodes, suggesting that an acute reduction of blood supply was responsible for the transient ischemia. A reduction of peak dp/dt and systolic pressure and elevation of end-diastolic pressure preceded and accompanied the ST change as observed in the animal upon sudden coronary occlusion. The hemodynamic pattern and the incidence of arrhythmias was the same in the episodes with or without pain. Coronary arteriography performed during a spontaneous episode in four patients showed complete occlusion with proximal diffuse lumen reduction and no distal filling of the vessel supplying the myocardium corresponding to the ST-segment elevation relieved by nitroglycerin administration. Thus, it appears reasonable to assume that a coronary spasm may be the cause of the acute reduction of coronary blood supply responsible for the transient myocardial ischemia in these patients. Anginal pain appears to be only a possible concomitant symptom of acute myocardial ischemia. The pathogenesis of “spontaneous angina” was investigated in five patients with so-called variant angina. Electrocardiographic monitoring demonstrated that several ischemic episodes were asymptomatic. Right and left ventricular pressure monitoring during 26 episodes of ST-segment elevation and two of ST-segment depression demonstrated that no hemodynamic change indicative of increased myocardial demands ever preceded the episodes, suggesting that an acute reduction of blood supply was responsible for the transient ischemia. A reduction of peak dp/dt and systolic pressure and elevation of end-diastolic pressure preceded and accompanied the ST change as observed in the animal upon sudden coronary occlusion. The hemodynamic pattern and the incidence of arrhythmias was the same in the episodes with or without pain. Coronary arteriography performed during a spontaneous episode in four patients showed complete occlusion with proximal diffuse lumen reduction and no distal filling of the vessel supplying the myocardium corresponding to the ST-segment elevation relieved by nitroglycerin administration. Thus, it appears reasonable to assume that a coronary spasm may be the cause of the acute reduction of coronary blood supply responsible for the transient myocardial ischemia in these patients. Anginal pain appears to be only a possible concomitant symptom of acute myocardial ischemia." @default.
- W2044339393 created "2016-06-24" @default.
- W2044339393 creator A5006414712 @default.
- W2044339393 creator A5024951617 @default.
- W2044339393 creator A5037864486 @default.
- W2044339393 creator A5043593248 @default.
- W2044339393 creator A5061640802 @default.
- W2044339393 creator A5069537078 @default.
- W2044339393 date "1975-11-01" @default.
- W2044339393 modified "2023-10-14" @default.
- W2044339393 title "Coronary Artery Spasm as a Cause of Acute Myocardial Ischemia in Man" @default.
- W2044339393 cites W1968369410 @default.
- W2044339393 cites W1986654292 @default.
- W2044339393 cites W1994745735 @default.
- W2044339393 cites W2007093460 @default.
- W2044339393 cites W2008006948 @default.
- W2044339393 cites W2016970202 @default.
- W2044339393 cites W2017631258 @default.
- W2044339393 cites W2019943765 @default.
- W2044339393 cites W2021456091 @default.
- W2044339393 cites W2024237176 @default.
- W2044339393 cites W2026762559 @default.
- W2044339393 cites W2030973682 @default.
- W2044339393 cites W2044212043 @default.
- W2044339393 cites W2056033365 @default.
- W2044339393 cites W2072992417 @default.
- W2044339393 cites W2081792304 @default.
- W2044339393 cites W2081857752 @default.
- W2044339393 cites W2086285226 @default.
- W2044339393 cites W2087971768 @default.
- W2044339393 cites W2089309175 @default.
- W2044339393 cites W2105777916 @default.
- W2044339393 cites W2121703558 @default.
- W2044339393 cites W2154629338 @default.
- W2044339393 cites W2163687862 @default.
- W2044339393 cites W2341028909 @default.
- W2044339393 cites W2400442228 @default.
- W2044339393 cites W2415655453 @default.
- W2044339393 doi "https://doi.org/10.1378/chest.68.5.625" @default.
- W2044339393 hasPublicationYear "1975" @default.
- W2044339393 type Work @default.
- W2044339393 sameAs 2044339393 @default.
- W2044339393 citedByCount "375" @default.
- W2044339393 countsByYear W20443393932012 @default.
- W2044339393 countsByYear W20443393932013 @default.
- W2044339393 countsByYear W20443393932014 @default.
- W2044339393 countsByYear W20443393932015 @default.
- W2044339393 countsByYear W20443393932016 @default.
- W2044339393 countsByYear W20443393932017 @default.
- W2044339393 countsByYear W20443393932021 @default.
- W2044339393 countsByYear W20443393932022 @default.
- W2044339393 countsByYear W20443393932023 @default.
- W2044339393 crossrefType "journal-article" @default.
- W2044339393 hasAuthorship W2044339393A5006414712 @default.
- W2044339393 hasAuthorship W2044339393A5024951617 @default.
- W2044339393 hasAuthorship W2044339393A5037864486 @default.
- W2044339393 hasAuthorship W2044339393A5043593248 @default.
- W2044339393 hasAuthorship W2044339393A5061640802 @default.
- W2044339393 hasAuthorship W2044339393A5069537078 @default.
- W2044339393 hasConcept C126322002 @default.
- W2044339393 hasConcept C164705383 @default.
- W2044339393 hasConcept C178853913 @default.
- W2044339393 hasConcept C2771771 @default.
- W2044339393 hasConcept C2776268601 @default.
- W2044339393 hasConcept C2776291336 @default.
- W2044339393 hasConcept C2776820930 @default.
- W2044339393 hasConcept C2777910003 @default.
- W2044339393 hasConcept C2778425758 @default.
- W2044339393 hasConcept C2778704086 @default.
- W2044339393 hasConcept C2780393670 @default.
- W2044339393 hasConcept C500558357 @default.
- W2044339393 hasConcept C541997718 @default.
- W2044339393 hasConcept C71924100 @default.
- W2044339393 hasConcept C84393581 @default.
- W2044339393 hasConceptScore W2044339393C126322002 @default.
- W2044339393 hasConceptScore W2044339393C164705383 @default.
- W2044339393 hasConceptScore W2044339393C178853913 @default.
- W2044339393 hasConceptScore W2044339393C2771771 @default.
- W2044339393 hasConceptScore W2044339393C2776268601 @default.
- W2044339393 hasConceptScore W2044339393C2776291336 @default.
- W2044339393 hasConceptScore W2044339393C2776820930 @default.
- W2044339393 hasConceptScore W2044339393C2777910003 @default.
- W2044339393 hasConceptScore W2044339393C2778425758 @default.
- W2044339393 hasConceptScore W2044339393C2778704086 @default.
- W2044339393 hasConceptScore W2044339393C2780393670 @default.
- W2044339393 hasConceptScore W2044339393C500558357 @default.
- W2044339393 hasConceptScore W2044339393C541997718 @default.
- W2044339393 hasConceptScore W2044339393C71924100 @default.
- W2044339393 hasConceptScore W2044339393C84393581 @default.
- W2044339393 hasIssue "5" @default.
- W2044339393 hasLocation W20443393931 @default.
- W2044339393 hasOpenAccess W2044339393 @default.
- W2044339393 hasPrimaryLocation W20443393931 @default.
- W2044339393 hasRelatedWork W1529194925 @default.
- W2044339393 hasRelatedWork W1995917068 @default.
- W2044339393 hasRelatedWork W2052535434 @default.
- W2044339393 hasRelatedWork W2061437179 @default.
- W2044339393 hasRelatedWork W2155095884 @default.