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- W2044357207 abstract "Nucleotide excision repair (NER) pathways remove a wide variety of bulky and helix-distorting lesions from DNA, and involve the coordinated action of damage detection, helicase and nuclease proteins. Most archaeal genomes encode eucaryal-type NER proteins, including the helicases XPB and XPD and nuclease XPF. These have been a valuable resource, yielding important mechanistic and structural insights relevant to human health. However, the nature of archaeal NER remains very uncertain. Here we review recent studies of archaeal NER proteins relevant to both eucaryal and archaeal NER systems and the evolution of repair pathways." @default.
- W2044357207 created "2016-06-24" @default.
- W2044357207 creator A5056651625 @default.
- W2044357207 creator A5057021821 @default.
- W2044357207 date "2011-01-01" @default.
- W2044357207 modified "2023-10-02" @default.
- W2044357207 title "The evolution and mechanisms of nucleotide excision repair proteins" @default.
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- W2044357207 doi "https://doi.org/10.1016/j.resmic.2010.09.003" @default.
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