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- W2044360939 abstract "A method of isolating neoblasts from Dugesia dorotocephala and the process of their aggregation in vitro are described. Morphology and behavior of gastrodermal cells and fixed parenchyma cells in vitro are also reported. Basically the neoblast is an oval cell with a large primary process and a finer secondary process at the opposite pole. Neoblasts have strong mutual affinity and very little affinity with other types of cells. The only observed method of locomotion of neoblasts in vitro was the contraction of the firmly attached primary processes between two or more neoblasts, which ends in their aggregation. Gastrodermal cells and fixed parenchyma cells are the most active migratory cells in vitro. With the observation of the cell movement both in vitro and in the fragments of the body, it was concluded that the primary accumulation of neoblasts at the open wound is not due to the active migration of neoblasts from the intact region as surmised by some other authors but due to the aggregation of local neoblasts. The migration of gastrodermal cells from the wound area causes the condensation of the parenchyma at the wound; the cytolyses of cells other than neoblasts in the parenchyma under a hypotonic condition evoke the aggregation of neoblasts. Active mitosis increases the number of neoblasts in the regeneration blastema. The “Parenchymal movement” or the mobility of the fixed parenchyma cells which must be responsible for the cellular transportation in the parenchyma was discussed." @default.
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- W2044360939 date "1967-04-01" @default.
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- W2044360939 title "Isolation of planarian neoblasts and their behaviorin Vitro with some aspects of the mechanism of the formation of regeneration blastema" @default.
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- W2044360939 doi "https://doi.org/10.1002/jez.1401640310" @default.
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