FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044363407> ?p ?o ?g. }

• W2044363407 endingPage "895" @default.
• W2044363407 startingPage "885" @default.
• W2044363407 abstract "In this study, the effect of cell alignment on proliferation and phenotype expression of rat bone marrow derived osteoblasts on micropatterned (MP) PHBV and P(L/D,L)LA films with 27 microm wide parallel microgrooves was investigated. Immobilization of fibrinogen (Fb) on film surface by adsorption increased hydrophilicity, while covalent immobilization decreased it. Amount of Fb immobilized was significantly higher upon covalent bonding (153.1+/-42.4 microg Fb/cm2) than when adsorbed (10.0+/-3.3 microg Fb/cm2). It was observed that the presence of MP did not influence cell proliferation in the long run. Osteoblasts on MP films with adsorbed (MP Fb(a)) and covalently immobilized Fb (MP Fb(i)) aligned parallel to the groove axis with mean deviation angles of 10.59+/-23.47 and 29.02+/-33.03 degrees, respectively, while on tissue culture polystyrene (TCP), on unpatterned films (UNP) and on UNP with adsorbed Fb (UNP Fb(a)) alignment with an arbitrary axis was much higher: 46.66+/-24.98, 48.72+/-31.19, 47.74+/-27.29 degrees, respectively. Fb-free MP films were not effective in cell alignment, and clumps were formed. Cell alignment achieved on MP Fb(a) films did not influence cell proliferation, but increased differentiation, as shown by ALP activity per cell and the evenness and the amount of calcium phosphate deposition. It was concluded that orientation of cells was influential on their differentiation and also, MP cell carriers with chemical cues on their surfaces are important in improving tissue repair." @default.
• W2044363407 created "2016-06-24" @default.
• W2044363407 creator A5004346273 @default.
• W2044363407 creator A5010487644 @default.
• W2044363407 creator A5016941067 @default.
• W2044363407 date "2006-02-01" @default.
• W2044363407 modified "2023-10-14" @default.
• W2044363407 title "Tissue engineering of bone on micropatterned biodegradable polyester films" @default.
• W2044363407 cites W1514050185 @default.
• W2044363407 cites W1698518057 @default.
• W2044363407 cites W1748311474 @default.
• W2044363407 cites W1967060076 @default.
• W2044363407 cites W1982365233 @default.
• W2044363407 cites W1983794369 @default.
• W2044363407 cites W1986612792 @default.
• W2044363407 cites W1987656041 @default.
• W2044363407 cites W1990899954 @default.
• W2044363407 cites W2005226698 @default.
• W2044363407 cites W2012163473 @default.
• W2044363407 cites W2014257478 @default.
• W2044363407 cites W2014451845 @default.
• W2044363407 cites W2020048727 @default.
• W2044363407 cites W2028062130 @default.
• W2044363407 cites W2028814820 @default.
• W2044363407 cites W2048993028 @default.
• W2044363407 cites W2051474403 @default.
• W2044363407 cites W2054171565 @default.
• W2044363407 cites W2058656906 @default.
• W2044363407 cites W2065317828 @default.
• W2044363407 cites W2070096452 @default.
• W2044363407 cites W2075755310 @default.
• W2044363407 cites W2088519183 @default.
• W2044363407 cites W2113152085 @default.
• W2044363407 cites W2128635872 @default.
• W2044363407 cites W2163563942 @default.
• W2044363407 cites W2166987361 @default.
• W2044363407 cites W2346124523 @default.
• W2044363407 doi "https://doi.org/10.1016/j.biomaterials.2005.07.001" @default.
• W2044363407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16143391" @default.
• W2044363407 hasPublicationYear "2006" @default.
• W2044363407 type Work @default.
• W2044363407 sameAs 2044363407 @default.
• W2044363407 citedByCount "63" @default.
• W2044363407 countsByYear W20443634072012 @default.
• W2044363407 countsByYear W20443634072013 @default.
• W2044363407 countsByYear W20443634072014 @default.
• W2044363407 countsByYear W20443634072015 @default.
• W2044363407 countsByYear W20443634072016 @default.
• W2044363407 countsByYear W20443634072017 @default.
• W2044363407 countsByYear W20443634072018 @default.
• W2044363407 countsByYear W20443634072019 @default.
• W2044363407 countsByYear W20443634072020 @default.
• W2044363407 crossrefType "journal-article" @default.
• W2044363407 hasAuthorship W2044363407A5004346273 @default.
• W2044363407 hasAuthorship W2044363407A5010487644 @default.
• W2044363407 hasAuthorship W2044363407A5016941067 @default.
• W2044363407 hasConcept C119394753 @default.
• W2044363407 hasConcept C12554922 @default.
• W2044363407 hasConcept C1491633281 @default.
• W2044363407 hasConcept C150394285 @default.
• W2044363407 hasConcept C159985019 @default.
• W2044363407 hasConcept C178790620 @default.
• W2044363407 hasConcept C180577832 @default.
• W2044363407 hasConcept C185592680 @default.
• W2044363407 hasConcept C192562407 @default.
• W2044363407 hasConcept C2777922577 @default.
• W2044363407 hasConcept C521977710 @default.
• W2044363407 hasConcept C55493867 @default.
• W2044363407 hasConcept C62112901 @default.
• W2044363407 hasConcept C86803240 @default.
• W2044363407 hasConcept C88001094 @default.
• W2044363407 hasConceptScore W2044363407C119394753 @default.
• W2044363407 hasConceptScore W2044363407C12554922 @default.
• W2044363407 hasConceptScore W2044363407C1491633281 @default.
• W2044363407 hasConceptScore W2044363407C150394285 @default.
• W2044363407 hasConceptScore W2044363407C159985019 @default.
• W2044363407 hasConceptScore W2044363407C178790620 @default.
• W2044363407 hasConceptScore W2044363407C180577832 @default.
• W2044363407 hasConceptScore W2044363407C185592680 @default.
• W2044363407 hasConceptScore W2044363407C192562407 @default.
• W2044363407 hasConceptScore W2044363407C2777922577 @default.
• W2044363407 hasConceptScore W2044363407C521977710 @default.
• W2044363407 hasConceptScore W2044363407C55493867 @default.
• W2044363407 hasConceptScore W2044363407C62112901 @default.
• W2044363407 hasConceptScore W2044363407C86803240 @default.
• W2044363407 hasConceptScore W2044363407C88001094 @default.
• W2044363407 hasIssue "6" @default.
• W2044363407 hasLocation W20443634071 @default.
• W2044363407 hasLocation W20443634072 @default.
• W2044363407 hasOpenAccess W2044363407 @default.
• W2044363407 hasPrimaryLocation W20443634071 @default.
• W2044363407 hasRelatedWork W1796081043 @default.
• W2044363407 hasRelatedWork W1968883002 @default.
• W2044363407 hasRelatedWork W1970585851 @default.
• W2044363407 hasRelatedWork W1997616240 @default.
• W2044363407 hasRelatedWork W2075861635 @default.
• W2044363407 hasRelatedWork W2371010590 @default.
• W2044363407 hasRelatedWork W2533770197 @default.

• next