FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044397935> ?p ?o ?g. }

• W2044397935 endingPage "341" @default.
• W2044397935 startingPage "331" @default.
• W2044397935 abstract "An Escherichia coli strain carrying either the secAcsR11 or Δ secG :: kan mutation is unable to grow at low temperature owing to cold‐sensitive protein translocation but grows normally at 37°C. However, introduction of the two mutations into the same cells caused a severe defect in protein translocation and the cells were unable to grow at any temperature examined, indicating that secG is essential for the secAcsR11 mutant. The mutant SecA (csSecA) was found to possess a single amino acid substitution in the precursor‐binding region and was defective in the interaction with the precursor protein. Furthermore, the membrane insertion of SecA and the membrane topology inversion of SecG, both of which took place upon the initiation of protein translocation, were significantly retarded even at 37°C, when csSecA was used instead of the wild‐type SecA. The insertion of the wild‐type SecA was also significantly defective when SecG‐depleted membrane vesicles were used in place of SecG‐containing ones. No insertion of csSecA occurred into SecG‐depleted membrane vesicles. Examination of in vitro protein translocation at 37°C revealed that SecG is essential for csSecA‐dependent protein translocation. We conclude that SecG and SecA undergo a coupled structure change, that is critical for efficient protein translocation." @default.
• W2044397935 created "2016-06-24" @default.
• W2044397935 creator A5025863828 @default.
• W2044397935 creator A5054054935 @default.
• W2044397935 creator A5085641802 @default.
• W2044397935 date "1998-07-01" @default.
• W2044397935 modified "2023-10-03" @default.
• W2044397935 title "Coupled structure change of SecA and SecG revealed by the synthetic lethality of the<i>secAcsR11</i>and Δ<i>secG</i>::<i>kan</i>double mutant" @default.
• W2044397935 cites W127362080 @default.
• W2044397935 cites W1511406372 @default.
• W2044397935 cites W1521948336 @default.
• W2044397935 cites W1534817676 @default.
• W2044397935 cites W1536082130 @default.
• W2044397935 cites W1540843979 @default.
• W2044397935 cites W1572793754 @default.
• W2044397935 cites W1584878924 @default.
• W2044397935 cites W1587008866 @default.
• W2044397935 cites W1587893698 @default.
• W2044397935 cites W1600437556 @default.
• W2044397935 cites W1602373369 @default.
• W2044397935 cites W1626287517 @default.
• W2044397935 cites W1649309172 @default.
• W2044397935 cites W1666626663 @default.
• W2044397935 cites W1751156858 @default.
• W2044397935 cites W17566691 @default.
• W2044397935 cites W1775749144 @default.
• W2044397935 cites W1899105020 @default.
• W2044397935 cites W1913648471 @default.
• W2044397935 cites W1923570112 @default.
• W2044397935 cites W1932645010 @default.
• W2044397935 cites W1946720111 @default.
• W2044397935 cites W1964517070 @default.
• W2044397935 cites W1965731203 @default.
• W2044397935 cites W1974902012 @default.
• W2044397935 cites W1978279776 @default.
• W2044397935 cites W1979080606 @default.
• W2044397935 cites W1986756715 @default.
• W2044397935 cites W2000489621 @default.
• W2044397935 cites W2022217156 @default.
• W2044397935 cites W2028622989 @default.
• W2044397935 cites W2030319704 @default.
• W2044397935 cites W2040338718 @default.
• W2044397935 cites W2042814467 @default.
• W2044397935 cites W2048052250 @default.
• W2044397935 cites W2048737734 @default.
• W2044397935 cites W2055274241 @default.
• W2044397935 cites W2056777456 @default.
• W2044397935 cites W2056891601 @default.
• W2044397935 cites W2061054863 @default.
• W2044397935 cites W2066537459 @default.
• W2044397935 cites W2067411581 @default.
• W2044397935 cites W2083553357 @default.
• W2044397935 cites W2083833295 @default.
• W2044397935 cites W2092131073 @default.
• W2044397935 cites W2093498871 @default.
• W2044397935 cites W2096207342 @default.
• W2044397935 cites W2100837269 @default.
• W2044397935 cites W2102004032 @default.
• W2044397935 cites W2119566573 @default.
• W2044397935 cites W2126106174 @default.
• W2044397935 cites W2134791113 @default.
• W2044397935 cites W2135216972 @default.
• W2044397935 cites W341831761 @default.
• W2044397935 cites W40140278 @default.
• W2044397935 cites W4242483402 @default.
• W2044397935 doi "https://doi.org/10.1046/j.1365-2958.1998.00937.x" @default.
• W2044397935 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9701825" @default.
• W2044397935 hasPublicationYear "1998" @default.
• W2044397935 type Work @default.
• W2044397935 sameAs 2044397935 @default.
• W2044397935 citedByCount "48" @default.
• W2044397935 countsByYear W20443979352012 @default.
• W2044397935 countsByYear W20443979352014 @default.
• W2044397935 countsByYear W20443979352015 @default.
• W2044397935 countsByYear W20443979352016 @default.
• W2044397935 countsByYear W20443979352019 @default.
• W2044397935 countsByYear W20443979352022 @default.
• W2044397935 crossrefType "journal-article" @default.
• W2044397935 hasAuthorship W2044397935A5025863828 @default.
• W2044397935 hasAuthorship W2044397935A5054054935 @default.
• W2044397935 hasAuthorship W2044397935A5085641802 @default.
• W2044397935 hasBestOaLocation W20443979351 @default.
• W2044397935 hasConcept C104317684 @default.
• W2044397935 hasConcept C138626823 @default.
• W2044397935 hasConcept C143065580 @default.
• W2044397935 hasConcept C207583985 @default.
• W2044397935 hasConcept C501734568 @default.
• W2044397935 hasConcept C54355233 @default.
• W2044397935 hasConcept C86803240 @default.
• W2044397935 hasConcept C95444343 @default.
• W2044397935 hasConceptScore W2044397935C104317684 @default.
• W2044397935 hasConceptScore W2044397935C138626823 @default.
• W2044397935 hasConceptScore W2044397935C143065580 @default.
• W2044397935 hasConceptScore W2044397935C207583985 @default.
• W2044397935 hasConceptScore W2044397935C501734568 @default.
• W2044397935 hasConceptScore W2044397935C54355233 @default.
• W2044397935 hasConceptScore W2044397935C86803240 @default.
• W2044397935 hasConceptScore W2044397935C95444343 @default.

• next