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- W204440100 abstract "Portopulmonary hypertension (PPHT) is a life-threatening respiratory complication of portal hypertension that can lead to right ventricular failure and is associated with a high mortality rate in advanced liver disease.1,2 PPHT is defined as pulmonary arterial hypertension (PAH) associated with portal hypertension, with or without hepatic disease, but it most commonly occurs in the setting of cirrhosis. Portal hypertension, rather than the presence of underlying liver disease, appears to be the main determining factor for the development of PAH.1 In the past, PPHT has been associated with older age, more severe liver disease, and presence of comorbidities. Recent observations have also shown a higher risk in women.3 The incidence of PPHT is as high as 6% among patients being evaluated for liver transplantation (who are routinely screened for PPHT since transplantation may be contraindicated in severe cases of PPHT).3,4" @default.
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- W204440100 date "2012-06-01" @default.
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- W204440100 title "Pulmonary arterial hypertension: an unusual cause of portal hypertension." @default.
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