FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044410633> ?p ?o ?g. }

• W2044410633 endingPage "161" @default.
• W2044410633 startingPage "143" @default.
• W2044410633 abstract "Poultry represents an important source of Salmonella infection in man. Despite intensive research on immunity, little is known about the involvement of T cell sub-populations in the immunological response of chickens against infection with non-host-adapted Salmonella ( S. ) serovars. In this study, the T cell composition of blood lymphocytes (CD4 + CD8 + ; CD4 + CD8 − ; CD4 − CD8 + ; CD8 + TcR1 + ; CD8 − TcR1 + , CD8 + TcR1 − ) after oral administration of the non-attenuated S. typhimurium wild-type strain 421 (infection) or the attenuated vaccine strain Salmonella vac ® T (immunization) to day-old chicks was investigated and compared with non-treated chickens by flow cytofluorometry. Additionally, the occurrence of T cell sub-populations (CD4 + ; CD8 + ; TcR1 + (γδ); TcR2 + (αβ 1 )) in ceca, spleen and bursa of Fabricius of the birds was studied immunohistologically. Blood samples and tissues were examined between days 1 and 12 of age. Chicks inoculated with S. typhimurium 421 or Salmonella vac ® T showed significantly elevated percentages of CD8 + TcR1 + in blood on days 7, 8 and 9, or on day 8 in comparison to control animals. The CD4 to CD8 cell ratio was about 3:1 in infected animals on day 5 of age. In the organs of treated chicks the numbers of CD8 + (γδ) and TcR1 + (γδ) cells had markedly increased on days 4 and 5 in ceca, 8 and 9 in the bursa and 9 and 12 in the spleen. Moreover, infected or vaccinated birds revealed larger quantities of CD4 + and TcR2 + T cells in ceca on days 4 and 5. As shown by double staining, the TcR1 + cells in the organs of infected animals additionally carried the CD8 antigen. In conclusion, immunization of day-old chicks with the attenuated Salmonella live vaccine strain resulted in the same changes in T cell composition as seen after infection with the non-attenuated Salmonella wild-type strain, but at a lower level. The remarkable increase of CD8 + TcR1 + (γδ) double positive cells in treated birds indicates an important role of this cell sub-population in the immunological defense of chickens against Salmonella exposure." @default.
• W2044410633 created "2016-06-24" @default.
• W2044410633 creator A5064367342 @default.
• W2044410633 creator A5075132809 @default.
• W2044410633 date "2001-01-01" @default.
• W2044410633 modified "2023-09-24" @default.
• W2044410633 title "Gamma/delta T cell response of chickens after oral administration of attenuated and non-attenuated Salmonella typhimurium strains" @default.
• W2044410633 cites W158670553 @default.
• W2044410633 cites W1821573328 @default.
• W2044410633 cites W1970378017 @default.
• W2044410633 cites W1970798343 @default.
• W2044410633 cites W1977415998 @default.
• W2044410633 cites W1977456564 @default.
• W2044410633 cites W1990958272 @default.
• W2044410633 cites W2008272948 @default.
• W2044410633 cites W2018975124 @default.
• W2044410633 cites W2019113825 @default.
• W2044410633 cites W2020791008 @default.
• W2044410633 cites W2021993298 @default.
• W2044410633 cites W2023263300 @default.
• W2044410633 cites W2026287371 @default.
• W2044410633 cites W2032070521 @default.
• W2044410633 cites W2045939638 @default.
• W2044410633 cites W2048888579 @default.
• W2044410633 cites W2055906361 @default.
• W2044410633 cites W2056624962 @default.
• W2044410633 cites W2056942869 @default.
• W2044410633 cites W2058156858 @default.
• W2044410633 cites W2069040645 @default.
• W2044410633 cites W2069884205 @default.
• W2044410633 cites W2071691077 @default.
• W2044410633 cites W2072163707 @default.
• W2044410633 cites W2075316373 @default.
• W2044410633 cites W2085992091 @default.
• W2044410633 cites W2096482972 @default.
• W2044410633 cites W2099401468 @default.
• W2044410633 cites W2120089620 @default.
• W2044410633 cites W2122752441 @default.
• W2044410633 cites W2133045083 @default.
• W2044410633 cites W2145065705 @default.
• W2044410633 cites W2150825662 @default.
• W2044410633 cites W2169318719 @default.
• W2044410633 cites W233458999 @default.
• W2044410633 cites W2904433322 @default.
• W2044410633 cites W4300100337 @default.
• W2044410633 cites W4302309074 @default.
• W2044410633 cites W2071718960 @default.
• W2044410633 doi "https://doi.org/10.1016/s0165-2427(00)00264-6" @default.
• W2044410633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11182154" @default.
• W2044410633 hasPublicationYear "2001" @default.
• W2044410633 type Work @default.
• W2044410633 sameAs 2044410633 @default.
• W2044410633 citedByCount "105" @default.
• W2044410633 countsByYear W20444106332012 @default.
• W2044410633 countsByYear W20444106332013 @default.
• W2044410633 countsByYear W20444106332014 @default.
• W2044410633 countsByYear W20444106332015 @default.
• W2044410633 countsByYear W20444106332016 @default.
• W2044410633 countsByYear W20444106332017 @default.
• W2044410633 countsByYear W20444106332018 @default.
• W2044410633 countsByYear W20444106332019 @default.
• W2044410633 countsByYear W20444106332020 @default.
• W2044410633 countsByYear W20444106332021 @default.
• W2044410633 countsByYear W20444106332022 @default.
• W2044410633 countsByYear W20444106332023 @default.
• W2044410633 crossrefType "journal-article" @default.
• W2044410633 hasAuthorship W2044410633A5064367342 @default.
• W2044410633 hasAuthorship W2044410633A5075132809 @default.
• W2044410633 hasConcept C10389963 @default.
• W2044410633 hasConcept C104317684 @default.
• W2044410633 hasConcept C159047783 @default.
• W2044410633 hasConcept C167672396 @default.
• W2044410633 hasConcept C180032290 @default.
• W2044410633 hasConcept C196978929 @default.
• W2044410633 hasConcept C203014093 @default.
• W2044410633 hasConcept C2779341262 @default.
• W2044410633 hasConcept C2779607309 @default.
• W2044410633 hasConcept C2780931953 @default.
• W2044410633 hasConcept C2781065037 @default.
• W2044410633 hasConcept C523546767 @default.
• W2044410633 hasConcept C54355233 @default.
• W2044410633 hasConcept C54602769 @default.
• W2044410633 hasConcept C55493867 @default.
• W2044410633 hasConcept C60987743 @default.
• W2044410633 hasConcept C86803240 @default.
• W2044410633 hasConcept C8891405 @default.
• W2044410633 hasConcept C89423630 @default.
• W2044410633 hasConceptScore W2044410633C10389963 @default.
• W2044410633 hasConceptScore W2044410633C104317684 @default.
• W2044410633 hasConceptScore W2044410633C159047783 @default.
• W2044410633 hasConceptScore W2044410633C167672396 @default.
• W2044410633 hasConceptScore W2044410633C180032290 @default.
• W2044410633 hasConceptScore W2044410633C196978929 @default.
• W2044410633 hasConceptScore W2044410633C203014093 @default.
• W2044410633 hasConceptScore W2044410633C2779341262 @default.
• W2044410633 hasConceptScore W2044410633C2779607309 @default.
• W2044410633 hasConceptScore W2044410633C2780931953 @default.
• W2044410633 hasConceptScore W2044410633C2781065037 @default.

• next