FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044424168> ?p ?o ?g. }

• W2044424168 endingPage "591" @default.
• W2044424168 startingPage "588" @default.
• W2044424168 abstract "Amphiregulin (Ar) and Cripto (Cr) are autocrine growth factors for mammary cells and both have been observed to exhibit high expression in human mammary tumors, in contrast with adjacent tissues. To investigate whether Ar and Cr play roles in the progression of mammary cell proliferation to unregulated growth and tumor formation, the levels of expression were examined in transgenic mice (TGM) that over-express several different oncogenes: MMTV-Polyoma virus middle T antigen (MMTV-PyMT), MMTV-c-ErbB2 (c-neu, HER2) and MT-hTGF alpha. These transgenic mice all produce mammary tumors but with different rates of progression. The levels of Ar were induced up to 10-fold in association with hyperplasia in 2 of the TGM. Cr overexpression was consistently observed in hyperplastic mammary glands in all the animal models, decreasing in overt tumors in 2 of the TGM models. In MMTV-PyMT mammary glands, the levels of Cr expression rose 7- to 10-fold in hyperplastic tissue and 25-fold the levels in tumors compared to age-matched transgene negative mice. Ar and especially Cr thus should have potential value as markers of preneoplastic change in mammary tissue." @default.
• W2044424168 created "2016-06-24" @default.
• W2044424168 creator A5003865388 @default.
• W2044424168 creator A5035986455 @default.
• W2044424168 creator A5081883286 @default.
• W2044424168 creator A5082162425 @default.
• W2044424168 date "1999-05-17" @default.
• W2044424168 modified "2023-10-18" @default.
• W2044424168 title "Preneoplastic mammary tumor markers: Cripto and amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice" @default.
• W2044424168 cites W1557616402 @default.
• W2044424168 cites W1595575599 @default.
• W2044424168 cites W1950601528 @default.
• W2044424168 cites W1972359995 @default.
• W2044424168 cites W1973033337 @default.
• W2044424168 cites W1982093899 @default.
• W2044424168 cites W1982882974 @default.
• W2044424168 cites W2007256480 @default.
• W2044424168 cites W2007418448 @default.
• W2044424168 cites W2015376103 @default.
• W2044424168 cites W2046802065 @default.
• W2044424168 cites W2099518877 @default.
• W2044424168 cites W2111449140 @default.
• W2044424168 cites W2155361926 @default.
• W2044424168 cites W2159735215 @default.
• W2044424168 cites W2321607498 @default.
• W2044424168 doi "https://doi.org/10.1002/(sici)1097-0215(19990517)81:4<588::aid-ijc14>3.0.co;2-i" @default.
• W2044424168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10225449" @default.
• W2044424168 hasPublicationYear "1999" @default.
• W2044424168 type Work @default.
• W2044424168 sameAs 2044424168 @default.
• W2044424168 citedByCount "34" @default.
• W2044424168 countsByYear W20444241682019 @default.
• W2044424168 crossrefType "journal-article" @default.
• W2044424168 hasAuthorship W2044424168A5003865388 @default.
• W2044424168 hasAuthorship W2044424168A5035986455 @default.
• W2044424168 hasAuthorship W2044424168A5081883286 @default.
• W2044424168 hasAuthorship W2044424168A5082162425 @default.
• W2044424168 hasBestOaLocation W20444241681 @default.
• W2044424168 hasConcept C102230213 @default.
• W2044424168 hasConcept C104317684 @default.
• W2044424168 hasConcept C121608353 @default.
• W2044424168 hasConcept C128240485 @default.
• W2044424168 hasConcept C134018914 @default.
• W2044424168 hasConcept C141035611 @default.
• W2044424168 hasConcept C142724271 @default.
• W2044424168 hasConcept C203014093 @default.
• W2044424168 hasConcept C2522874641 @default.
• W2044424168 hasConcept C2776187077 @default.
• W2044424168 hasConcept C2776362946 @default.
• W2044424168 hasConcept C2777562237 @default.
• W2044424168 hasConcept C2778001805 @default.
• W2044424168 hasConcept C2779256057 @default.
• W2044424168 hasConcept C2779777497 @default.
• W2044424168 hasConcept C2780394083 @default.
• W2044424168 hasConcept C2780806702 @default.
• W2044424168 hasConcept C502942594 @default.
• W2044424168 hasConcept C530470458 @default.
• W2044424168 hasConcept C54355233 @default.
• W2044424168 hasConcept C55493867 @default.
• W2044424168 hasConcept C71924100 @default.
• W2044424168 hasConcept C81885089 @default.
• W2044424168 hasConcept C86803240 @default.
• W2044424168 hasConceptScore W2044424168C102230213 @default.
• W2044424168 hasConceptScore W2044424168C104317684 @default.
• W2044424168 hasConceptScore W2044424168C121608353 @default.
• W2044424168 hasConceptScore W2044424168C128240485 @default.
• W2044424168 hasConceptScore W2044424168C134018914 @default.
• W2044424168 hasConceptScore W2044424168C141035611 @default.
• W2044424168 hasConceptScore W2044424168C142724271 @default.
• W2044424168 hasConceptScore W2044424168C203014093 @default.
• W2044424168 hasConceptScore W2044424168C2522874641 @default.
• W2044424168 hasConceptScore W2044424168C2776187077 @default.
• W2044424168 hasConceptScore W2044424168C2776362946 @default.
• W2044424168 hasConceptScore W2044424168C2777562237 @default.
• W2044424168 hasConceptScore W2044424168C2778001805 @default.
• W2044424168 hasConceptScore W2044424168C2779256057 @default.
• W2044424168 hasConceptScore W2044424168C2779777497 @default.
• W2044424168 hasConceptScore W2044424168C2780394083 @default.
• W2044424168 hasConceptScore W2044424168C2780806702 @default.
• W2044424168 hasConceptScore W2044424168C502942594 @default.
• W2044424168 hasConceptScore W2044424168C530470458 @default.
• W2044424168 hasConceptScore W2044424168C54355233 @default.
• W2044424168 hasConceptScore W2044424168C55493867 @default.
• W2044424168 hasConceptScore W2044424168C71924100 @default.
• W2044424168 hasConceptScore W2044424168C81885089 @default.
• W2044424168 hasConceptScore W2044424168C86803240 @default.
• W2044424168 hasIssue "4" @default.
• W2044424168 hasLocation W20444241681 @default.
• W2044424168 hasLocation W20444241682 @default.
• W2044424168 hasLocation W20444241683 @default.
• W2044424168 hasOpenAccess W2044424168 @default.
• W2044424168 hasPrimaryLocation W20444241681 @default.
• W2044424168 hasRelatedWork W1488158769 @default.
• W2044424168 hasRelatedWork W1523608178 @default.
• W2044424168 hasRelatedWork W1616357803 @default.
• W2044424168 hasRelatedWork W2044424168 @default.
• W2044424168 hasRelatedWork W2071120972 @default.
• W2044424168 hasRelatedWork W2099518877 @default.

• next