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• W2044427708 abstract "The role of aneuploidy in carcinogenesis has long been debated. We argue here that aneuploid genomes are naturally more susceptible to the types of chromosome rearrangement and epigenetic aberration that are found typically in tumor cells. In some cases, the formation of an aneuploid genome might be the initiating step in neoplastic conversion." @default.
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• W2044427708 date "2003-05-01" @default.
• W2044427708 modified "2023-09-26" @default.
• W2044427708 title "Does the intrinsic instability of aneuploid genomes have a causal role in cancer?" @default.
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• W2044427708 doi "https://doi.org/10.1016/s0168-9525(03)00057-x" @default.
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