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- W2044429761 abstract "Many reports indicate that prolactin has a role in puberty occurrence. The present study was developed to evaluate the action of pituitary grafts on puberty. Female rats grafted on day 21 with adult' (90 days old) or young' (21 days old) pituitaries showed precocious vaginal opening and first estrus. The puberty advancement induced by adult' transplants was due to an increase in plasma prolactin values and can be blocked by bromocriptine treatment. The puberty advancement induced by young' transplants was not associated with increased prolactin levels and cannot be blocked by bromocriptine. These results suggest the existence of two possible mechanisms in precocious puberty induced by pituitary grafts: a prolactin-dependent one and another one not directly related with prolactin." @default.
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- W2044429761 date "1986-01-01" @default.
- W2044429761 modified "2023-10-17" @default.
- W2044429761 title "Two Possible Mechanisms for Precocious Puberty Induced in Female Rats by Pituitary Grafts" @default.
- W2044429761 doi "https://doi.org/10.1159/000124458" @default.
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