Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044432824> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2044432824 abstract "Abstract The yolk sac perfusion technique whereby the yolk of embryos is replaced by defined media was used to study the effect of phenylalanine and tyrosine deficiency on 4- to 7-day-old chick embryos. The omission of either amino acid from the perfusion medium resulted in reduced growth and extensive degeneration of the eyes and central nervous system within 24 hours of perfusion. The histological effects were identical for both amino acids except for failure of eye pigmentation which was characteristic of tyrosine deficiency. Both deficiencies resulted in severe degeneration of the neural retina and brain, scattered pycnosis in the spinal cord and cranial and spinal ganglia, and vacuolization of the lens in the region of lens fiber development. With the exception of the lens the effects of phenylalanine and tyrosine deficiency appeared to be restricted to tissues of neural origin. In an experiment conducted to determine the ability of phenylalanine to substitute for tyrosine, the addition of phenylalanine to the perfusion medium not only failed to relieve the symptoms of tyrosine deficiency, but it caused a reduction of eye pigmentation when the concentration of tyrosine was marginally inadequate. The inability of 4- to 6-day-old chick embryos to convert phenylalanine to tyrosine was confirmed by radioactive tracer studies." @default.
- W2044432824 created "2016-06-24" @default.
- W2044432824 creator A5066588296 @default.
- W2044432824 creator A5076053092 @default.
- W2044432824 date "1971-05-01" @default.
- W2044432824 modified "2023-09-27" @default.
- W2044432824 title "Degeneration of the eyes and central nervous system of chick embryos subjected to phenylalanine or tyrosine deficiency" @default.
- W2044432824 cites W1874455821 @default.
- W2044432824 cites W1988886820 @default.
- W2044432824 cites W1993146491 @default.
- W2044432824 cites W2001415635 @default.
- W2044432824 cites W2006549367 @default.
- W2044432824 cites W2021121116 @default.
- W2044432824 cites W2021160874 @default.
- W2044432824 cites W2026912546 @default.
- W2044432824 cites W2034322703 @default.
- W2044432824 cites W2039545886 @default.
- W2044432824 cites W2047637701 @default.
- W2044432824 cites W2057316725 @default.
- W2044432824 cites W2057826825 @default.
- W2044432824 cites W2063641615 @default.
- W2044432824 cites W2081689999 @default.
- W2044432824 cites W2088831286 @default.
- W2044432824 cites W20938829 @default.
- W2044432824 cites W2108500866 @default.
- W2044432824 cites W2129239998 @default.
- W2044432824 cites W2131324691 @default.
- W2044432824 cites W2131643813 @default.
- W2044432824 doi "https://doi.org/10.1016/0012-1606(71)90025-x" @default.
- W2044432824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5105039" @default.
- W2044432824 hasPublicationYear "1971" @default.
- W2044432824 type Work @default.
- W2044432824 sameAs 2044432824 @default.
- W2044432824 citedByCount "8" @default.
- W2044432824 countsByYear W20444328242012 @default.
- W2044432824 countsByYear W20444328242015 @default.
- W2044432824 countsByYear W20444328242016 @default.
- W2044432824 crossrefType "journal-article" @default.
- W2044432824 hasAuthorship W2044432824A5066588296 @default.
- W2044432824 hasAuthorship W2044432824A5076053092 @default.
- W2044432824 hasConcept C126322002 @default.
- W2044432824 hasConcept C134018914 @default.
- W2044432824 hasConcept C142724271 @default.
- W2044432824 hasConcept C18903297 @default.
- W2044432824 hasConcept C196843134 @default.
- W2044432824 hasConcept C2776165026 @default.
- W2044432824 hasConcept C2777043721 @default.
- W2044432824 hasConcept C2777431362 @default.
- W2044432824 hasConcept C2778614373 @default.
- W2044432824 hasConcept C2779354088 @default.
- W2044432824 hasConcept C2781321622 @default.
- W2044432824 hasConcept C515207424 @default.
- W2044432824 hasConcept C529278444 @default.
- W2044432824 hasConcept C55493867 @default.
- W2044432824 hasConcept C71924100 @default.
- W2044432824 hasConcept C86803240 @default.
- W2044432824 hasConcept C95444343 @default.
- W2044432824 hasConceptScore W2044432824C126322002 @default.
- W2044432824 hasConceptScore W2044432824C134018914 @default.
- W2044432824 hasConceptScore W2044432824C142724271 @default.
- W2044432824 hasConceptScore W2044432824C18903297 @default.
- W2044432824 hasConceptScore W2044432824C196843134 @default.
- W2044432824 hasConceptScore W2044432824C2776165026 @default.
- W2044432824 hasConceptScore W2044432824C2777043721 @default.
- W2044432824 hasConceptScore W2044432824C2777431362 @default.
- W2044432824 hasConceptScore W2044432824C2778614373 @default.
- W2044432824 hasConceptScore W2044432824C2779354088 @default.
- W2044432824 hasConceptScore W2044432824C2781321622 @default.
- W2044432824 hasConceptScore W2044432824C515207424 @default.
- W2044432824 hasConceptScore W2044432824C529278444 @default.
- W2044432824 hasConceptScore W2044432824C55493867 @default.
- W2044432824 hasConceptScore W2044432824C71924100 @default.
- W2044432824 hasConceptScore W2044432824C86803240 @default.
- W2044432824 hasConceptScore W2044432824C95444343 @default.
- W2044432824 hasLocation W20444328241 @default.
- W2044432824 hasLocation W20444328242 @default.
- W2044432824 hasOpenAccess W2044432824 @default.
- W2044432824 hasPrimaryLocation W20444328241 @default.
- W2044432824 hasRelatedWork W1513881935 @default.
- W2044432824 hasRelatedWork W1980936780 @default.
- W2044432824 hasRelatedWork W2044432824 @default.
- W2044432824 hasRelatedWork W2057410200 @default.
- W2044432824 hasRelatedWork W2062365651 @default.
- W2044432824 hasRelatedWork W2066530401 @default.
- W2044432824 hasRelatedWork W2075368133 @default.
- W2044432824 hasRelatedWork W2095561130 @default.
- W2044432824 hasRelatedWork W2147713970 @default.
- W2044432824 hasRelatedWork W2316850797 @default.
- W2044432824 isParatext "false" @default.
- W2044432824 isRetracted "false" @default.
- W2044432824 magId "2044432824" @default.
- W2044432824 workType "article" @default.