FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044449451> ?p ?o ?g. }

• W2044449451 endingPage "446" @default.
• W2044449451 startingPage "440" @default.
• W2044449451 abstract "Accelerated partial-breast irradiation (PBI) is a new treatment paradigm for patients with early-stage breast cancer. Although PBI may lead to greater local recurrence rates, it may be cost-effective because of better tolerability and lower cost. We aim to determine the incremental cost-effectiveness of PBI compared with whole-breast radiation therapy (WBRT) for estrogen receptor-positive postmenopausal women treated for early-stage breast cancer.We developed a Markov model to describe health states in the 15 years after radiotherapy for early-stage breast cancer. External beam (EB) and MammoSite (MS) PBI were considered and assumed to be equally effective, but carried different costs. Patients received tamoxifen, but not chemotherapy. Utilities, recurrence risks, and costs were adapted from the literature; the baseline utility for no disease after radiotherapy was set at 0.92. Probabilistic sensitivity analyses were performed to model uncertainty in the PBI hazard ratio, recurrence pattern, and patient utilities. Costs (in 2004 US dollars) and quality-adjusted life-years were discounted at 3%/y.The incremental cost-effectiveness ratio for WBRT compared with EB-PBI was $630,000/quality-adjusted life-year; WBRT strongly dominated MS-PBI. One-way sensitivity analysis found that results were sensitive to PBI hazard ratio, recurrence pattern, baseline recurrence risk, and no evidence of disease PBI utility values. Probabilistic sensitivity showed that EB-PBI was the most cost-effective technique over a wide range of assumptions and societal willingness-to-pay values.EB-PBI was the most cost-effective strategy for postmenopausal women with early-stage breast cancer. Unless the quality of life after MS-PBI proves to be superior, it is unlikely to be cost-effective." @default.
• W2044449451 created "2016-06-24" @default.
• W2044449451 creator A5011724315 @default.
• W2044449451 creator A5018558600 @default.
• W2044449451 creator A5025500663 @default.
• W2044449451 creator A5072565409 @default.
• W2044449451 creator A5073305219 @default.
• W2044449451 date "2009-06-01" @default.
• W2044449451 modified "2023-10-16" @default.
• W2044449451 title "Partial-Breast Irradiation Versus Whole-Breast Irradiation for Early-Stage Breast Cancer: A Cost-Effectiveness Analysis" @default.
• W2044449451 cites W1748731440 @default.
• W2044449451 cites W1861968279 @default.
• W2044449451 cites W1880798787 @default.
• W2044449451 cites W1913795200 @default.
• W2044449451 cites W1965734230 @default.
• W2044449451 cites W1974846727 @default.
• W2044449451 cites W2009224696 @default.
• W2044449451 cites W2022684250 @default.
• W2044449451 cites W2025767387 @default.
• W2044449451 cites W2026188008 @default.
• W2044449451 cites W2028720836 @default.
• W2044449451 cites W2044658894 @default.
• W2044449451 cites W2056857722 @default.
• W2044449451 cites W2070156026 @default.
• W2044449451 cites W2076090101 @default.
• W2044449451 cites W2094889889 @default.
• W2044449451 cites W2132434084 @default.
• W2044449451 cites W2135979535 @default.
• W2044449451 cites W2158615473 @default.
• W2044449451 cites W2164654252 @default.
• W2044449451 cites W2166631738 @default.
• W2044449451 doi "https://doi.org/10.1016/j.ijrobp.2008.08.015" @default.
• W2044449451 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2695677" @default.
• W2044449451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18963542" @default.
• W2044449451 hasPublicationYear "2009" @default.
• W2044449451 type Work @default.
• W2044449451 sameAs 2044449451 @default.
• W2044449451 citedByCount "60" @default.
• W2044449451 countsByYear W20444494512012 @default.
• W2044449451 countsByYear W20444494512013 @default.
• W2044449451 countsByYear W20444494512014 @default.
• W2044449451 countsByYear W20444494512015 @default.
• W2044449451 countsByYear W20444494512016 @default.
• W2044449451 countsByYear W20444494512017 @default.
• W2044449451 countsByYear W20444494512018 @default.
• W2044449451 countsByYear W20444494512019 @default.
• W2044449451 countsByYear W20444494512021 @default.
• W2044449451 countsByYear W20444494512022 @default.
• W2044449451 countsByYear W20444494512023 @default.
• W2044449451 crossrefType "journal-article" @default.
• W2044449451 hasAuthorship W2044449451A5011724315 @default.
• W2044449451 hasAuthorship W2044449451A5018558600 @default.
• W2044449451 hasAuthorship W2044449451A5025500663 @default.
• W2044449451 hasAuthorship W2044449451A5072565409 @default.
• W2044449451 hasAuthorship W2044449451A5073305219 @default.
• W2044449451 hasBestOaLocation W20444494512 @default.
• W2044449451 hasConcept C112930515 @default.
• W2044449451 hasConcept C121608353 @default.
• W2044449451 hasConcept C126322002 @default.
• W2044449451 hasConcept C143998085 @default.
• W2044449451 hasConcept C146357865 @default.
• W2044449451 hasConcept C151730666 @default.
• W2044449451 hasConcept C159110408 @default.
• W2044449451 hasConcept C207103383 @default.
• W2044449451 hasConcept C2777176818 @default.
• W2044449451 hasConcept C2779951463 @default.
• W2044449451 hasConcept C3019080777 @default.
• W2044449451 hasConcept C44249647 @default.
• W2044449451 hasConcept C509974204 @default.
• W2044449451 hasConcept C530470458 @default.
• W2044449451 hasConcept C64332521 @default.
• W2044449451 hasConcept C71924100 @default.
• W2044449451 hasConcept C86803240 @default.
• W2044449451 hasConceptScore W2044449451C112930515 @default.
• W2044449451 hasConceptScore W2044449451C121608353 @default.
• W2044449451 hasConceptScore W2044449451C126322002 @default.
• W2044449451 hasConceptScore W2044449451C143998085 @default.
• W2044449451 hasConceptScore W2044449451C146357865 @default.
• W2044449451 hasConceptScore W2044449451C151730666 @default.
• W2044449451 hasConceptScore W2044449451C159110408 @default.
• W2044449451 hasConceptScore W2044449451C207103383 @default.
• W2044449451 hasConceptScore W2044449451C2777176818 @default.
• W2044449451 hasConceptScore W2044449451C2779951463 @default.
• W2044449451 hasConceptScore W2044449451C3019080777 @default.
• W2044449451 hasConceptScore W2044449451C44249647 @default.
• W2044449451 hasConceptScore W2044449451C509974204 @default.
• W2044449451 hasConceptScore W2044449451C530470458 @default.
• W2044449451 hasConceptScore W2044449451C64332521 @default.
• W2044449451 hasConceptScore W2044449451C71924100 @default.
• W2044449451 hasConceptScore W2044449451C86803240 @default.
• W2044449451 hasIssue "2" @default.
• W2044449451 hasLocation W20444494511 @default.
• W2044449451 hasLocation W20444494512 @default.
• W2044449451 hasLocation W20444494513 @default.
• W2044449451 hasLocation W20444494514 @default.
• W2044449451 hasOpenAccess W2044449451 @default.
• W2044449451 hasPrimaryLocation W20444494511 @default.
• W2044449451 hasRelatedWork W1771722205 @default.

• next