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• W2044455349 abstract "Background:The previous reports have demonstrated that coronary artery flow profiles might change in patie- nts with aortic valve disease. Our objective was to assess phasic coronary artery flow and velocity characteristics and coronary flow reserve in patients with severe aortic vale disease. Method:We studied six patients (4 men and 2 women, mean age 61.3±6.3 years with aortic regurgitation and seven patients (3 men and 4 women, mean age 66.3±10.3 years with aortic stenosis. Coronary flow velocity was measured at the proximal portion of left anterior descending artery with 0.014-inch Doppler tipped guide wire and intracoronary injection of adenosine. Nineteen patients (11 men and 8 women, mean age 52±9.8 years with normal coronary artery were served as normal control. Result:The velocity-time integral of systolic coronary flow (SPVi was significantly higher in patient with severe aortic regurgitation than control (21.1±5 vs 9.4±3.1, p 0.05, respe- ctively. Coronary flow reserve was significantly decreased in patient with aortic valve disease compared with control subject (2.1±0.8 vs 3.2±0.4 p<0.05, respectively. Conclusion:Coronary flow reserve decreased signi- ficantly in patients with AR and with AS compared with normal control. Coronary blood flow profiles in patients with AR was characterized by systolic flow predominance and reduced diastolic flow whereas patients with AS was a tendency toward decreased systolic flow and increased diastolic flow. ( ( ( (Korean Circulation J 1998;28" @default.
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• W2044455349 date "1998-01-01" @default.
• W2044455349 modified "2023-09-27" @default.
• W2044455349 title "Phasic Coronary Artery Flow Profiles in Patients with Aortic Valve Disease" @default.
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• W2044455349 doi "https://doi.org/10.4070/kcj.1998.28.10.1691" @default.
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