Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044498936> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2044498936 endingPage "5458" @default.
- W2044498936 startingPage "5451" @default.
- W2044498936 abstract "Adiponectin represents one of the most abundant and well-studied adipokines that has been implicated as a major protective factor against the adverse metabolic and cardiovascular consequences of obesity. The main insulin-sensitizing action of adiponectin results from decrease in hepatic gluconeogenesis and increase in muscle glucose transport and, secondly from enhancement of energy consumption and fatty acid oxidation in peripheral tissues with the aim of increasing ATP production. Besides these effects, the potential role of adiponectin on insulin secretion, as well as on energy expenditure, through central action, has also been investigated. Accumulating evidence from clinical, experimental animal and genetic studies support a close association between hypoadiponectinemia and insulin resistance/ type 2 diabetes. The question that arises is whether hypoadiponectinemia is the result of insulin resistance/type 2 diabetes or the cause of this disorder. Based on the observation that various drug classes exert beneficial effects on insulin resistance partly by increasing plasma adiponectin levels, it could hypothesized that substances that enhance or mimic adiponectin to activate its receptors and/or postreceptor signaling pathway may be a promising therapeutic strategy in the prevention and treatment of diabetes. However, many questions need to be addressed before adiponectin can be used as a potent therapeutic target. Keywords: Adiponectin, inflammation, insulin resistance, type 2 diabetes, visceral adipocity, Adiponectin, inflammation, insulin resistance, type 2 diabetes, visceral adipocity, abundant, pokines, metabolic, cardiovascular, sulin-sensitizing" @default.
- W2044498936 created "2016-06-24" @default.
- W2044498936 creator A5071253541 @default.
- W2044498936 creator A5083401082 @default.
- W2044498936 date "2012-10-01" @default.
- W2044498936 modified "2023-10-14" @default.
- W2044498936 title "Adiponectin in Diabetes Mellitus" @default.
- W2044498936 doi "https://doi.org/10.2174/092986712803833182" @default.
- W2044498936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22876922" @default.
- W2044498936 hasPublicationYear "2012" @default.
- W2044498936 type Work @default.
- W2044498936 sameAs 2044498936 @default.
- W2044498936 citedByCount "39" @default.
- W2044498936 countsByYear W20444989362013 @default.
- W2044498936 countsByYear W20444989362014 @default.
- W2044498936 countsByYear W20444989362015 @default.
- W2044498936 countsByYear W20444989362016 @default.
- W2044498936 countsByYear W20444989362017 @default.
- W2044498936 countsByYear W20444989362018 @default.
- W2044498936 countsByYear W20444989362019 @default.
- W2044498936 countsByYear W20444989362020 @default.
- W2044498936 countsByYear W20444989362021 @default.
- W2044498936 countsByYear W20444989362022 @default.
- W2044498936 countsByYear W20444989362023 @default.
- W2044498936 crossrefType "journal-article" @default.
- W2044498936 hasAuthorship W2044498936A5071253541 @default.
- W2044498936 hasAuthorship W2044498936A5083401082 @default.
- W2044498936 hasConcept C126322002 @default.
- W2044498936 hasConcept C134018914 @default.
- W2044498936 hasConcept C194832188 @default.
- W2044498936 hasConcept C2776782570 @default.
- W2044498936 hasConcept C2777180221 @default.
- W2044498936 hasConcept C2777391703 @default.
- W2044498936 hasConcept C2779306644 @default.
- W2044498936 hasConcept C2780578515 @default.
- W2044498936 hasConcept C2910068830 @default.
- W2044498936 hasConcept C555293320 @default.
- W2044498936 hasConcept C71924100 @default.
- W2044498936 hasConceptScore W2044498936C126322002 @default.
- W2044498936 hasConceptScore W2044498936C134018914 @default.
- W2044498936 hasConceptScore W2044498936C194832188 @default.
- W2044498936 hasConceptScore W2044498936C2776782570 @default.
- W2044498936 hasConceptScore W2044498936C2777180221 @default.
- W2044498936 hasConceptScore W2044498936C2777391703 @default.
- W2044498936 hasConceptScore W2044498936C2779306644 @default.
- W2044498936 hasConceptScore W2044498936C2780578515 @default.
- W2044498936 hasConceptScore W2044498936C2910068830 @default.
- W2044498936 hasConceptScore W2044498936C555293320 @default.
- W2044498936 hasConceptScore W2044498936C71924100 @default.
- W2044498936 hasIssue "32" @default.
- W2044498936 hasLocation W20444989361 @default.
- W2044498936 hasLocation W20444989362 @default.
- W2044498936 hasOpenAccess W2044498936 @default.
- W2044498936 hasPrimaryLocation W20444989361 @default.
- W2044498936 hasRelatedWork W128033378 @default.
- W2044498936 hasRelatedWork W1749231158 @default.
- W2044498936 hasRelatedWork W1987892777 @default.
- W2044498936 hasRelatedWork W2023128145 @default.
- W2044498936 hasRelatedWork W2068642455 @default.
- W2044498936 hasRelatedWork W2353152665 @default.
- W2044498936 hasRelatedWork W2364422503 @default.
- W2044498936 hasRelatedWork W2794329614 @default.
- W2044498936 hasRelatedWork W2912842488 @default.
- W2044498936 hasRelatedWork W3172217040 @default.
- W2044498936 hasVolume "19" @default.
- W2044498936 isParatext "false" @default.
- W2044498936 isRetracted "false" @default.
- W2044498936 magId "2044498936" @default.
- W2044498936 workType "article" @default.