FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044503368> ?p ?o ?g. }

• W2044503368 abstract "Standard distal esophageal pH monitoring data are sometimes within normal ranges in children with clinically suspected gastroesophageal reflux disease. Therefore, the authors hypothesized that the amount of acid reflux reaching the proximal esophagus may be greater in some subgroups of patients than in healthy controls or in other subgroups of patients.The parameters of 24-hour pH monitoring in the proximal part of the esophagus were analyzed in 120 symptomatic infants in who the reflux parameters in the lower esophagus were clearly within normal ranges (reflux index < 5.0%). The infants were classified into four patient groups: excessive regurgitation (n = 41): inconsolable crying (n = 31), apparent life-threatening event (ALTE) (n = 18), and chronic respiratory disorders (n = 30). The control group consisted also of 120 infants. The following parameters were calculated: reflux index, the number of reflux episodes, the number of reflux episodes lasting longer than 5 minutes, the duration of the longest reflux episode, and the acid clearance time (ACT, duration of reflux episodes divided by number of reflux episodes).The patients with chronic respiratory disorders were significantly older than the patients in the other groups and the controls. In the distal esophagus, there was no statistically significant difference between the reflux parameters. As could be expected, every parameter was statistically (paired t test, Wilcoxon signed-rank test) significantly smaller in the proximal than in the distal esophagus, except for the ACT in infants who presented with inconsolable crying. In the proximal esophagus, there was no statistically significant difference between the different patient subgroups or controls, except for the number of reflux episodes in the group with chronic respiratory disorders and the group with inconsolable crying, applying one-way analysis of variance. As determined by applying the Mann-Whitney test, the number of reflux episodes in the upper esophagus was significantly higher in the group with chronic respiratory disorders than in the other patient groups and controls. Therefore, the authors' data do not support the hypothesis that reflux reaching the proximal esophagus is a frequent cause of ALTE. However, the data may suggest that the number of reflux episodes reaching the proximal esophagus in children with chronic respiratory disorders and with distal pH monitoring data within normal ranges may be increased. Whether this finding reflects reality or a statistical coincidence, or is influenced by the older age of this patient group, needs further evaluation.In theory, dual simultaneous esophageal pH monitoring in the distal and proximal esophagus may increase the diagnostic accuracy of pH monitoring in infants. Our results do not support a substantial advantage of a systematic application of this new technique, especially not in infants presenting with ALTE, excessive regurgitation, or inconsolable crying. In the subgroup of patients with chronic respiratory disorders, more data are needed before conclusions can be determined and recommendations can be made." @default.
• W2044503368 created "2016-06-24" @default.
• W2044503368 creator A5005169031 @default.
• W2044503368 creator A5028204221 @default.
• W2044503368 creator A5039144132 @default.
• W2044503368 creator A5046124886 @default.
• W2044503368 creator A5046445835 @default.
• W2044503368 creator A5074808590 @default.
• W2044503368 creator A5080730036 @default.
• W2044503368 date "2001-03-01" @default.
• W2044503368 modified "2023-09-24" @default.
• W2044503368 title "pH Monitoring in the Distal and Proximal Esophagus in Symptomatic Infants" @default.
• W2044503368 cites W1490422948 @default.
• W2044503368 cites W1997917746 @default.
• W2044503368 cites W2018899980 @default.
• W2044503368 cites W2022774950 @default.
• W2044503368 cites W2034975868 @default.
• W2044503368 cites W2037138631 @default.
• W2044503368 cites W2059405681 @default.
• W2044503368 cites W2085926793 @default.
• W2044503368 cites W2099961904 @default.
• W2044503368 cites W2129356190 @default.
• W2044503368 cites W2139518623 @default.
• W2044503368 doi "https://doi.org/10.1097/00005176-200103000-00005" @default.
• W2044503368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11345172" @default.
• W2044503368 hasPublicationYear "2001" @default.
• W2044503368 type Work @default.
• W2044503368 sameAs 2044503368 @default.
• W2044503368 citedByCount "30" @default.
• W2044503368 countsByYear W20445033682012 @default.
• W2044503368 countsByYear W20445033682013 @default.
• W2044503368 countsByYear W20445033682014 @default.
• W2044503368 countsByYear W20445033682019 @default.
• W2044503368 crossrefType "journal-article" @default.
• W2044503368 hasAuthorship W2044503368A5005169031 @default.
• W2044503368 hasAuthorship W2044503368A5028204221 @default.
• W2044503368 hasAuthorship W2044503368A5039144132 @default.
• W2044503368 hasAuthorship W2044503368A5046124886 @default.
• W2044503368 hasAuthorship W2044503368A5046445835 @default.
• W2044503368 hasAuthorship W2044503368A5074808590 @default.
• W2044503368 hasAuthorship W2044503368A5080730036 @default.
• W2044503368 hasConcept C118552586 @default.
• W2044503368 hasConcept C126322002 @default.
• W2044503368 hasConcept C2777014526 @default.
• W2044503368 hasConcept C2777819096 @default.
• W2044503368 hasConcept C2778013503 @default.
• W2044503368 hasConcept C2779134260 @default.
• W2044503368 hasConcept C2779949763 @default.
• W2044503368 hasConcept C2780168065 @default.
• W2044503368 hasConcept C43270747 @default.
• W2044503368 hasConcept C71924100 @default.
• W2044503368 hasConcept C90924648 @default.
• W2044503368 hasConceptScore W2044503368C118552586 @default.
• W2044503368 hasConceptScore W2044503368C126322002 @default.
• W2044503368 hasConceptScore W2044503368C2777014526 @default.
• W2044503368 hasConceptScore W2044503368C2777819096 @default.
• W2044503368 hasConceptScore W2044503368C2778013503 @default.
• W2044503368 hasConceptScore W2044503368C2779134260 @default.
• W2044503368 hasConceptScore W2044503368C2779949763 @default.
• W2044503368 hasConceptScore W2044503368C2780168065 @default.
• W2044503368 hasConceptScore W2044503368C43270747 @default.
• W2044503368 hasConceptScore W2044503368C71924100 @default.
• W2044503368 hasConceptScore W2044503368C90924648 @default.
• W2044503368 hasLocation W20445033681 @default.
• W2044503368 hasLocation W20445033682 @default.
• W2044503368 hasOpenAccess W2044503368 @default.
• W2044503368 hasPrimaryLocation W20445033681 @default.
• W2044503368 hasRelatedWork W1527897335 @default.
• W2044503368 hasRelatedWork W154085876 @default.
• W2044503368 hasRelatedWork W1605377084 @default.
• W2044503368 hasRelatedWork W2018670793 @default.
• W2044503368 hasRelatedWork W2019938783 @default.
• W2044503368 hasRelatedWork W2022774950 @default.
• W2044503368 hasRelatedWork W2046382987 @default.
• W2044503368 hasRelatedWork W2058730724 @default.
• W2044503368 hasRelatedWork W2061065284 @default.
• W2044503368 hasRelatedWork W2072419995 @default.
• W2044503368 hasRelatedWork W2075008048 @default.
• W2044503368 hasRelatedWork W2085926793 @default.
• W2044503368 hasRelatedWork W2091149260 @default.
• W2044503368 hasRelatedWork W2129356190 @default.
• W2044503368 hasRelatedWork W2164253938 @default.
• W2044503368 hasRelatedWork W2168079854 @default.
• W2044503368 hasRelatedWork W2374182057 @default.
• W2044503368 hasRelatedWork W2409007911 @default.
• W2044503368 hasRelatedWork W2409360061 @default.
• W2044503368 hasRelatedWork W2371475834 @default.
• W2044503368 isParatext "false" @default.
• W2044503368 isRetracted "false" @default.
• W2044503368 magId "2044503368" @default.
• W2044503368 workType "article" @default.