FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044557619> ?p ?o ?g. }

• W2044557619 endingPage "30" @default.
• W2044557619 startingPage "23" @default.
• W2044557619 abstract "In order to provide new insight into the molecular mechanism of perforating trauma-induced cataract formation in an 8-week-old ddY mouse lens, we performed an in situ investigation into changes in the water-protein and/or protein-protein interactions by using 500 MHz (1)H-NMR spectroscopy, and into structural alterations in lens proteins by using Raman spectroscopy. Cross-relaxation times of water protons in the perforated opaque lens were considerably shorter than those in the intact transparent lens, whereas there was no significant difference in water content, suggesting a drastic change in water-protein and protein-protein interactions in the perforated lens. In addition, there was no significant difference in the intensity ratios of several key Raman bands between intact and perforated lenses, indicating that no significant local and overall conformational changes in lens protein itself occur in the perforated lens. The present (1)H-NMR and Raman results lead us to the conclusion that changes leading to lens opacification in the perforating trauma-induced cataract appear to involve the rapid formation of immobile large lens protein aggregates without formation of intra- and intermolecular disulfide linkages, and rapid increase in a fraction of bound water associated with large protein aggregates." @default.
• W2044557619 created "2016-06-24" @default.
• W2044557619 creator A5004888598 @default.
• W2044557619 creator A5016291864 @default.
• W2044557619 creator A5040860122 @default.
• W2044557619 creator A5041953187 @default.
• W2044557619 creator A5067747021 @default.
• W2044557619 creator A5085657160 @default.
• W2044557619 date "2000-03-01" @default.
• W2044557619 modified "2023-10-11" @default.
• W2044557619 title "1H-NMR and Raman studies on perforating trauma-induced cataract formation in a mouse lens" @default.
• W2044557619 cites W1496659467 @default.
• W2044557619 cites W1595712808 @default.
• W2044557619 cites W1604646693 @default.
• W2044557619 cites W1963715550 @default.
• W2044557619 cites W1973637306 @default.
• W2044557619 cites W1986905389 @default.
• W2044557619 cites W1988313849 @default.
• W2044557619 cites W1994016889 @default.
• W2044557619 cites W1994402749 @default.
• W2044557619 cites W1995978907 @default.
• W2044557619 cites W1996473696 @default.
• W2044557619 cites W1998671619 @default.
• W2044557619 cites W2025128488 @default.
• W2044557619 cites W2026454029 @default.
• W2044557619 cites W2038753407 @default.
• W2044557619 cites W2045369412 @default.
• W2044557619 cites W2046740033 @default.
• W2044557619 cites W2047016397 @default.
• W2044557619 cites W2055622606 @default.
• W2044557619 cites W2068884281 @default.
• W2044557619 cites W2074724116 @default.
• W2044557619 cites W2075194735 @default.
• W2044557619 cites W2075875234 @default.
• W2044557619 cites W2082814077 @default.
• W2044557619 cites W2088358864 @default.
• W2044557619 cites W2094746737 @default.
• W2044557619 cites W2142744687 @default.
• W2044557619 cites W4298070597 @default.
• W2044557619 doi "https://doi.org/10.1016/s0304-4165(99)00220-2" @default.
• W2044557619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10699486" @default.
• W2044557619 hasPublicationYear "2000" @default.
• W2044557619 type Work @default.
• W2044557619 sameAs 2044557619 @default.
• W2044557619 citedByCount "9" @default.
• W2044557619 countsByYear W20445576192012 @default.
• W2044557619 countsByYear W20445576192013 @default.
• W2044557619 countsByYear W20445576192018 @default.
• W2044557619 crossrefType "journal-article" @default.
• W2044557619 hasAuthorship W2044557619A5004888598 @default.
• W2044557619 hasAuthorship W2044557619A5016291864 @default.
• W2044557619 hasAuthorship W2044557619A5040860122 @default.
• W2044557619 hasAuthorship W2044557619A5041953187 @default.
• W2044557619 hasAuthorship W2044557619A5067747021 @default.
• W2044557619 hasAuthorship W2044557619A5085657160 @default.
• W2044557619 hasConcept C118487528 @default.
• W2044557619 hasConcept C120665830 @default.
• W2044557619 hasConcept C121332964 @default.
• W2044557619 hasConcept C12554922 @default.
• W2044557619 hasConcept C126322002 @default.
• W2044557619 hasConcept C15336307 @default.
• W2044557619 hasConcept C185592680 @default.
• W2044557619 hasConcept C192562407 @default.
• W2044557619 hasConcept C2776029896 @default.
• W2044557619 hasConcept C2778257484 @default.
• W2044557619 hasConcept C2909093167 @default.
• W2044557619 hasConcept C40003534 @default.
• W2044557619 hasConcept C55493867 @default.
• W2044557619 hasConcept C66974803 @default.
• W2044557619 hasConcept C71240020 @default.
• W2044557619 hasConcept C71924100 @default.
• W2044557619 hasConcept C7263354 @default.
• W2044557619 hasConcept C86803240 @default.
• W2044557619 hasConceptScore W2044557619C118487528 @default.
• W2044557619 hasConceptScore W2044557619C120665830 @default.
• W2044557619 hasConceptScore W2044557619C121332964 @default.
• W2044557619 hasConceptScore W2044557619C12554922 @default.
• W2044557619 hasConceptScore W2044557619C126322002 @default.
• W2044557619 hasConceptScore W2044557619C15336307 @default.
• W2044557619 hasConceptScore W2044557619C185592680 @default.
• W2044557619 hasConceptScore W2044557619C192562407 @default.
• W2044557619 hasConceptScore W2044557619C2776029896 @default.
• W2044557619 hasConceptScore W2044557619C2778257484 @default.
• W2044557619 hasConceptScore W2044557619C2909093167 @default.
• W2044557619 hasConceptScore W2044557619C40003534 @default.
• W2044557619 hasConceptScore W2044557619C55493867 @default.
• W2044557619 hasConceptScore W2044557619C66974803 @default.
• W2044557619 hasConceptScore W2044557619C71240020 @default.
• W2044557619 hasConceptScore W2044557619C71924100 @default.
• W2044557619 hasConceptScore W2044557619C7263354 @default.
• W2044557619 hasConceptScore W2044557619C86803240 @default.
• W2044557619 hasIssue "1" @default.
• W2044557619 hasLocation W20445576191 @default.
• W2044557619 hasLocation W20445576192 @default.
• W2044557619 hasOpenAccess W2044557619 @default.
• W2044557619 hasPrimaryLocation W20445576191 @default.
• W2044557619 hasRelatedWork W1983218064 @default.
• W2044557619 hasRelatedWork W1989188250 @default.

• next