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• W2044583009 abstract "This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice for 7 days. Histological analysis demonstrated massive elongation of neurites from embryonic stem cell-derived neurons toward auditory hair cells. Embryonic stem cell-derived neurites were adjacent to or surrounding hair cells, and exhibited expression of synaptophysin, a marker for synaptic vesicles. These findings demonstrate the ability of embryonic stem cell-derived neurons for reinnervation into auditory epithelia, indicating a high potential of embryonic stem cell-derived neurons as transplants for replacing spiral ganglion neurons." @default.
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• W2044583009 date "2005-05-01" @default.
• W2044583009 modified "2023-10-16" @default.
• W2044583009 title "Innervation of stem cell-derived neurons into auditory epithelia of mice" @default.
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• W2044583009 doi "https://doi.org/10.1097/00001756-200505310-00001" @default.
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