FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044584560> ?p ?o ?g. }

• W2044584560 endingPage "189" @default.
• W2044584560 startingPage "168" @default.
• W2044584560 abstract "Methylphenidate (MPD) is considered as the first-line pharmacotherapy to treat ADHD. More recently, MPD has also been used as a cognitive enhancement recreationally. Its therapeutic effects are not fully understood, nor are the long term effects of the drug on brain development. The ventral tegmental area (VTA) neuronal activity was recorded from freely behaving adolescent rats using a wireless recording system. Five groups were used: saline, 0.6, 2.5, 5.0 and 10.0 mg/kg MPD. The experiment lasted for 10 days. This study demonstrated that VTA neurons respond to MPD in a dose response characteristic and the same dose of MPD can cause both behavioral sensitization and behavioral tolerance. The neuronal unit activity was evaluated based on the animals’ behavioral activity following chronic MPD administration. The study showed that the animals’ behavioral response to different acute MPD of 0.6, 2.5 and 10.0 mg/kg doses responded in a dose response characteristics. Moreover, the same chronic dose of 0.6, 2.5, and 10.0 mg/kg MPD elicits in some animals’ behavioral sensitization and in some others behavioral tolerance. Therefore, the neuronal activity recorded from animals expressing behavioral sensitization was analyzed separately from the neuronal activity recorded from of behaviorally tolerant animals and it was found that the VTA units of the behaviorally sensitization animals responded significantly different to the drug than those VTA units recorded from animals expressing behavioral tolerance." @default.
• W2044584560 created "2016-06-24" @default.
• W2044584560 creator A5007034132 @default.
• W2044584560 creator A5019962786 @default.
• W2044584560 creator A5043582034 @default.
• W2044584560 date "2014-01-01" @default.
• W2044584560 modified "2023-09-29" @default.
• W2044584560 title "Ventral Tegmental Area Neuronal Activity Correlates to Animals’ Behavioral Response to Chronic Methylphenidate Recorded from Adolescent SD Male Rats" @default.
• W2044584560 cites W1978140546 @default.
• W2044584560 cites W1978723139 @default.
• W2044584560 cites W1981847532 @default.
• W2044584560 cites W1983138582 @default.
• W2044584560 cites W1985420205 @default.
• W2044584560 cites W1986489012 @default.
• W2044584560 cites W1988309308 @default.
• W2044584560 cites W1988659186 @default.
• W2044584560 cites W1988746979 @default.
• W2044584560 cites W1999130725 @default.
• W2044584560 cites W1999408115 @default.
• W2044584560 cites W2001865657 @default.
• W2044584560 cites W2005307259 @default.
• W2044584560 cites W2007357434 @default.
• W2044584560 cites W2008264529 @default.
• W2044584560 cites W2009243814 @default.
• W2044584560 cites W2012924701 @default.
• W2044584560 cites W2016029955 @default.
• W2044584560 cites W2016929635 @default.
• W2044584560 cites W2020209931 @default.
• W2044584560 cites W2026010744 @default.
• W2044584560 cites W2029009210 @default.
• W2044584560 cites W2031361314 @default.
• W2044584560 cites W2035247507 @default.
• W2044584560 cites W2035319691 @default.
• W2044584560 cites W2036572502 @default.
• W2044584560 cites W2037430625 @default.
• W2044584560 cites W2040341158 @default.
• W2044584560 cites W2048139508 @default.
• W2044584560 cites W2056405954 @default.
• W2044584560 cites W2065048782 @default.
• W2044584560 cites W2066274594 @default.
• W2044584560 cites W2068319999 @default.
• W2044584560 cites W2075241411 @default.
• W2044584560 cites W2080040700 @default.
• W2044584560 cites W2084114882 @default.
• W2044584560 cites W2088916019 @default.
• W2044584560 cites W2089172972 @default.
• W2044584560 cites W2089985520 @default.
• W2044584560 cites W2091142535 @default.
• W2044584560 cites W2092792131 @default.
• W2044584560 cites W2095751605 @default.
• W2044584560 cites W2095857831 @default.
• W2044584560 cites W2095875127 @default.
• W2044584560 cites W2098677721 @default.
• W2044584560 cites W2103073726 @default.
• W2044584560 cites W2112124882 @default.
• W2044584560 cites W2112234785 @default.
• W2044584560 cites W2116504386 @default.
• W2044584560 cites W2117922300 @default.
• W2044584560 cites W2124264649 @default.
• W2044584560 cites W2134330719 @default.
• W2044584560 cites W2140513029 @default.
• W2044584560 cites W2151158926 @default.
• W2044584560 cites W2153915883 @default.
• W2044584560 cites W2156796433 @default.
• W2044584560 cites W2159447534 @default.
• W2044584560 cites W2172081237 @default.
• W2044584560 cites W2334483884 @default.
• W2044584560 doi "https://doi.org/10.4236/jbbs.2014.44020" @default.
• W2044584560 hasPublicationYear "2014" @default.
• W2044584560 type Work @default.
• W2044584560 sameAs 2044584560 @default.
• W2044584560 citedByCount "6" @default.
• W2044584560 countsByYear W20445845602014 @default.
• W2044584560 countsByYear W20445845602016 @default.
• W2044584560 countsByYear W20445845602017 @default.
• W2044584560 countsByYear W20445845602020 @default.
• W2044584560 countsByYear W20445845602022 @default.
• W2044584560 countsByYear W20445845602023 @default.
• W2044584560 crossrefType "journal-article" @default.
• W2044584560 hasAuthorship W2044584560A5007034132 @default.
• W2044584560 hasAuthorship W2044584560A5019962786 @default.
• W2044584560 hasAuthorship W2044584560A5043582034 @default.
• W2044584560 hasBestOaLocation W20445845601 @default.
• W2044584560 hasConcept C118552586 @default.
• W2044584560 hasConcept C137183658 @default.
• W2044584560 hasConcept C15744967 @default.
• W2044584560 hasConcept C169760540 @default.
• W2044584560 hasConcept C2776217527 @default.
• W2044584560 hasConcept C2776552330 @default.
• W2044584560 hasConcept C2777112843 @default.
• W2044584560 hasConcept C2777397205 @default.
• W2044584560 hasConcept C2780783007 @default.
• W2044584560 hasConcept C2780948874 @default.
• W2044584560 hasConcept C3019662062 @default.
• W2044584560 hasConcept C42219234 @default.
• W2044584560 hasConcept C513476851 @default.
• W2044584560 hasConcept C529278444 @default.
• W2044584560 hasConcept C71924100 @default.

• next