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- W2044590478 abstract "Intracerebral hemorrhage (ICH) is associated with higher mortality and morbidity than any other form of stroke. However, there currently are no treatments proven to improve outcomes after ICH, and therefore, new effective therapies are urgently needed. Growing insight into ICH pathophysiology has led to the development of neuroprotective strategies that aim to improve the outcome through reduction of secondary pathologic processes. Many neuroprotectants target molecules or pathways involved in hematoma degradation, inflammation or apoptosis, and have demonstrated potential clinical benefits in experimental settings. We extensively reviewed the current understanding of ICH pathophysiology as well as promising experimental neuroprotective agents with particular focus on their mechanisms of action. Continued advances in ICH knowledge, increased understanding of neuroprotective mechanisms, and improvement in the ability to modulate molecular and pathologic events with multitargeting agents will lead to successful clinical trials and bench-to-bedside translation of neuroprotective strategies." @default.
- W2044590478 created "2016-06-24" @default.
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- W2044590478 date "2010-12-21" @default.
- W2044590478 modified "2023-10-14" @default.
- W2044590478 title "Advances in Neuroprotective Strategies: Potential Therapies for Intracerebral Hemorrhage" @default.
- W2044590478 cites W102143045 @default.
- W2044590478 cites W110942310 @default.
- W2044590478 cites W1259690367 @default.
- W2044590478 cites W126515222 @default.
- W2044590478 cites W1562000342 @default.
- W2044590478 cites W1580441335 @default.
- W2044590478 cites W1712649196 @default.
- W2044590478 cites W1960350925 @default.
- W2044590478 cites W1970674339 @default.
- W2044590478 cites W1973393911 @default.
- W2044590478 cites W1974375510 @default.
- W2044590478 cites W1976081557 @default.
- W2044590478 cites W1977227142 @default.
- W2044590478 cites W1978733314 @default.
- W2044590478 cites W1980300082 @default.
- W2044590478 cites W1983148583 @default.
- W2044590478 cites W1986321526 @default.
- W2044590478 cites W1988519696 @default.
- W2044590478 cites W1990885249 @default.
- W2044590478 cites W1991512531 @default.
- W2044590478 cites W1993557217 @default.
- W2044590478 cites W1995567109 @default.
- W2044590478 cites W1996003447 @default.
- W2044590478 cites W1998557118 @default.
- W2044590478 cites W2000683036 @default.
- W2044590478 cites W2001162433 @default.
- W2044590478 cites W2002347737 @default.
- W2044590478 cites W2002766055 @default.
- W2044590478 cites W2006311748 @default.
- W2044590478 cites W2007690362 @default.
- W2044590478 cites W2009964551 @default.
- W2044590478 cites W2011893442 @default.
- W2044590478 cites W2014248364 @default.
- W2044590478 cites W2014963097 @default.
- W2044590478 cites W2015182670 @default.
- W2044590478 cites W2018504633 @default.
- W2044590478 cites W2019867783 @default.
- W2044590478 cites W2020847830 @default.
- W2044590478 cites W2021124405 @default.
- W2044590478 cites W2021867771 @default.
- W2044590478 cites W2021946435 @default.
- W2044590478 cites W2022123825 @default.
- W2044590478 cites W2023762785 @default.
- W2044590478 cites W2025461456 @default.
- W2044590478 cites W2027147813 @default.
- W2044590478 cites W2028557994 @default.
- W2044590478 cites W2030529426 @default.
- W2044590478 cites W2030883755 @default.
- W2044590478 cites W2034987918 @default.
- W2044590478 cites W2036192402 @default.
- W2044590478 cites W2040084521 @default.
- W2044590478 cites W2046329404 @default.
- W2044590478 cites W2046691672 @default.
- W2044590478 cites W2046801831 @default.
- W2044590478 cites W2049032159 @default.
- W2044590478 cites W2051253086 @default.
- W2044590478 cites W2051315914 @default.
- W2044590478 cites W2051645126 @default.
- W2044590478 cites W2054058695 @default.
- W2044590478 cites W2054135378 @default.
- W2044590478 cites W2055534742 @default.
- W2044590478 cites W2058323075 @default.
- W2044590478 cites W2058462157 @default.
- W2044590478 cites W2059640915 @default.
- W2044590478 cites W2061434349 @default.
- W2044590478 cites W2064723605 @default.
- W2044590478 cites W2065723024 @default.
- W2044590478 cites W2067633386 @default.
- W2044590478 cites W2069252203 @default.
- W2044590478 cites W2070206132 @default.
- W2044590478 cites W2070450284 @default.
- W2044590478 cites W2072205634 @default.
- W2044590478 cites W2072438077 @default.
- W2044590478 cites W2075122519 @default.
- W2044590478 cites W2076034559 @default.
- W2044590478 cites W2076762501 @default.
- W2044590478 cites W2079237158 @default.
- W2044590478 cites W2079398445 @default.
- W2044590478 cites W2080706272 @default.
- W2044590478 cites W2083029419 @default.
- W2044590478 cites W2083651501 @default.
- W2044590478 cites W2086065424 @default.
- W2044590478 cites W2091037537 @default.
- W2044590478 cites W2094424802 @default.