FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044609342> ?p ?o ?g. }

• W2044609342 endingPage "182" @default.
• W2044609342 startingPage "175" @default.
• W2044609342 abstract "Ischemia/reperfusion (I/R) injury in the skeletal muscle is inevitable in many vascular and musculoskeletal traumas, diseases, free tissue transfers, and during time-consuming reconstructive and transplantation surgeries. Although skeletal muscle has a higher tolerance to ischemia than other organs, prolonged ischemia can still result in significant complications, including muscle necrosis and apoptosis. One of the major goals in the treatment of ischemia is early restoration of blood flow (reperfusion) to the area at risk. However, reperfusion has led to a new pathophysiologic condition called “reperfusion injury,” a phenomenon which actually provokes a distinct degree of tissue injury. The purpose of this review is to examine the current state of understanding of I/R injury as well as to highlight recent developments on I/R interventions including our own experience in this particular field. We expect, as our acquired experience and the increased knowledge of underlying mechanisms of I/R injury, more effective interventions aimed to reduce I/R injury will be developed to interfere with or modulate this particular pathophysiologic processes. Ischemia/reperfusion (I/R) injury in the skeletal muscle is inevitable in many vascular and musculoskeletal traumas, diseases, free tissue transfers, and during time-consuming reconstructive and transplantation surgeries. Although skeletal muscle has a higher tolerance to ischemia than other organs, prolonged ischemia can still result in significant complications, including muscle necrosis and apoptosis. One of the major goals in the treatment of ischemia is early restoration of blood flow (reperfusion) to the area at risk. However, reperfusion has led to a new pathophysiologic condition called “reperfusion injury,” a phenomenon which actually provokes a distinct degree of tissue injury. The purpose of this review is to examine the current state of understanding of I/R injury as well as to highlight recent developments on I/R interventions including our own experience in this particular field. We expect, as our acquired experience and the increased knowledge of underlying mechanisms of I/R injury, more effective interventions aimed to reduce I/R injury will be developed to interfere with or modulate this particular pathophysiologic processes." @default.
• W2044609342 created "2016-06-24" @default.
• W2044609342 creator A5009882561 @default.
• W2044609342 creator A5045676440 @default.
• W2044609342 creator A5081857069 @default.
• W2044609342 date "2011-11-01" @default.
• W2044609342 modified "2023-09-25" @default.
• W2044609342 title "Therapeutic Interventions Against Reperfusion Injury in Skeletal Muscle" @default.
• W2044609342 cites W1851055496 @default.
• W2044609342 cites W1855724912 @default.
• W2044609342 cites W1964099886 @default.
• W2044609342 cites W1965693998 @default.
• W2044609342 cites W1968832307 @default.
• W2044609342 cites W1968948768 @default.
• W2044609342 cites W1969012353 @default.
• W2044609342 cites W1969336269 @default.
• W2044609342 cites W1969690844 @default.
• W2044609342 cites W1973144556 @default.
• W2044609342 cites W1976762311 @default.
• W2044609342 cites W1977225442 @default.
• W2044609342 cites W1978154423 @default.
• W2044609342 cites W1978221784 @default.
• W2044609342 cites W1979795076 @default.
• W2044609342 cites W1981636067 @default.
• W2044609342 cites W1983837006 @default.
• W2044609342 cites W1984613822 @default.
• W2044609342 cites W1993541391 @default.
• W2044609342 cites W2000282895 @default.
• W2044609342 cites W2001243514 @default.
• W2044609342 cites W2003427063 @default.
• W2044609342 cites W2004754488 @default.
• W2044609342 cites W2009324064 @default.
• W2044609342 cites W2013752873 @default.
• W2044609342 cites W2015437912 @default.
• W2044609342 cites W2016646368 @default.
• W2044609342 cites W2018198686 @default.
• W2044609342 cites W2018666280 @default.
• W2044609342 cites W2019075176 @default.
• W2044609342 cites W2022473516 @default.
• W2044609342 cites W2023685090 @default.
• W2044609342 cites W2024729321 @default.
• W2044609342 cites W2026770742 @default.
• W2044609342 cites W2026826353 @default.
• W2044609342 cites W2029872857 @default.
• W2044609342 cites W2033357754 @default.
• W2044609342 cites W2037121432 @default.
• W2044609342 cites W2037522411 @default.
• W2044609342 cites W2038133154 @default.
• W2044609342 cites W2038516718 @default.
• W2044609342 cites W2039182022 @default.
• W2044609342 cites W2041587518 @default.
• W2044609342 cites W2049086819 @default.
• W2044609342 cites W2049741856 @default.
• W2044609342 cites W2051740472 @default.
• W2044609342 cites W2052047569 @default.
• W2044609342 cites W2052538429 @default.
• W2044609342 cites W2054643117 @default.
• W2044609342 cites W2055251180 @default.
• W2044609342 cites W2058713290 @default.
• W2044609342 cites W2062356491 @default.
• W2044609342 cites W2068395093 @default.
• W2044609342 cites W2071249136 @default.
• W2044609342 cites W2072756792 @default.
• W2044609342 cites W2073938229 @default.
• W2044609342 cites W2079756336 @default.
• W2044609342 cites W2082988568 @default.
• W2044609342 cites W2083260812 @default.
• W2044609342 cites W2088022459 @default.
• W2044609342 cites W2100172993 @default.
• W2044609342 cites W2100340359 @default.
• W2044609342 cites W2107838881 @default.
• W2044609342 cites W2113999599 @default.
• W2044609342 cites W2116381281 @default.
• W2044609342 cites W2116603854 @default.
• W2044609342 cites W2120714892 @default.
• W2044609342 cites W2122179672 @default.
• W2044609342 cites W2130121105 @default.
• W2044609342 cites W2132494613 @default.
• W2044609342 cites W2132619897 @default.
• W2044609342 cites W2132867842 @default.
• W2044609342 cites W2132888316 @default.
• W2044609342 cites W2133506920 @default.
• W2044609342 cites W2137445925 @default.
• W2044609342 cites W2141300150 @default.
• W2044609342 cites W2141633621 @default.
• W2044609342 cites W2146217294 @default.
• W2044609342 cites W2148623295 @default.
• W2044609342 cites W2151492048 @default.
• W2044609342 cites W2156495678 @default.
• W2044609342 cites W2157879494 @default.
• W2044609342 cites W2160308360 @default.
• W2044609342 cites W2163365154 @default.
• W2044609342 cites W2164134552 @default.
• W2044609342 cites W2166531590 @default.
• W2044609342 cites W2169182236 @default.
• W2044609342 cites W2171873992 @default.
• W2044609342 cites W2313018523 @default.
• W2044609342 cites W2401559749 @default.

• next