Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044658510> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2044658510 endingPage "245" @default.
- W2044658510 startingPage "242" @default.
- W2044658510 abstract "Tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine proteinase inhibitor associated with the extracellular matrices of vascular cells. A recent report provided in vitro evidence that TFPI-2 may be a novel inhibitor of the matrix metalloproteinases MMP-1, MMP-13, MMP-2 and MMP-9. In studies aimed at identifying the structural elements of TFPI-2 mediating the putative inhibition of the above MMPs, we re-examined the ability of native TFPI-2 to form complexes with MMP-2, MMP-9 and MMP-1, as well as assess its ability to inhibit the proteolytic activity of the interstitial collagenase, activated MMP-1. We report here that TFPI-2 failed to form complexes with MMP-2, MMP-9 and MMP-1 as revealed in immunoprecipitation and ligand blotting studies. In addition, TFPI-2 had no influence on the proteolytic activity of activated MMP-1 towards triple-helical collagen. These data provide presumptive evidence that TFPI-2 does not bind to MMP-2, MMP-9 and MMP-1, or regulate MMP-1, in the extracellular matrix." @default.
- W2044658510 created "2016-06-24" @default.
- W2044658510 creator A5004491609 @default.
- W2044658510 creator A5012495384 @default.
- W2044658510 creator A5087563095 @default.
- W2044658510 date "2003-06-01" @default.
- W2044658510 modified "2023-10-14" @default.
- W2044658510 title "Human tissue factor pathway inhibitor-2 does not bind or inhibit activated matrix metalloproteinase-1" @default.
- W2044658510 cites W1562667342 @default.
- W2044658510 cites W1779806497 @default.
- W2044658510 cites W1968485086 @default.
- W2044658510 cites W2026906569 @default.
- W2044658510 cites W2040003226 @default.
- W2044658510 cites W2046195556 @default.
- W2044658510 cites W2078551518 @default.
- W2044658510 cites W2080786556 @default.
- W2044658510 cites W2094070957 @default.
- W2044658510 cites W2107218017 @default.
- W2044658510 cites W2108909942 @default.
- W2044658510 cites W2171780788 @default.
- W2044658510 doi "https://doi.org/10.1016/s0304-4165(03)00074-6" @default.
- W2044658510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12787920" @default.
- W2044658510 hasPublicationYear "2003" @default.
- W2044658510 type Work @default.
- W2044658510 sameAs 2044658510 @default.
- W2044658510 citedByCount "14" @default.
- W2044658510 countsByYear W20446585102015 @default.
- W2044658510 crossrefType "journal-article" @default.
- W2044658510 hasAuthorship W2044658510A5004491609 @default.
- W2044658510 hasAuthorship W2044658510A5012495384 @default.
- W2044658510 hasAuthorship W2044658510A5087563095 @default.
- W2044658510 hasConcept C104317684 @default.
- W2044658510 hasConcept C109523444 @default.
- W2044658510 hasConcept C126322002 @default.
- W2044658510 hasConcept C153911025 @default.
- W2044658510 hasConcept C181199279 @default.
- W2044658510 hasConcept C185592680 @default.
- W2044658510 hasConcept C186738567 @default.
- W2044658510 hasConcept C189165786 @default.
- W2044658510 hasConcept C2775958869 @default.
- W2044658510 hasConcept C2775965246 @default.
- W2044658510 hasConcept C2776414213 @default.
- W2044658510 hasConcept C2776747403 @default.
- W2044658510 hasConcept C2777151630 @default.
- W2044658510 hasConcept C2778382381 @default.
- W2044658510 hasConcept C2778394429 @default.
- W2044658510 hasConcept C28406088 @default.
- W2044658510 hasConcept C55493867 @default.
- W2044658510 hasConcept C55728118 @default.
- W2044658510 hasConcept C71829478 @default.
- W2044658510 hasConcept C71924100 @default.
- W2044658510 hasConcept C85265743 @default.
- W2044658510 hasConcept C86803240 @default.
- W2044658510 hasConcept C95444343 @default.
- W2044658510 hasConceptScore W2044658510C104317684 @default.
- W2044658510 hasConceptScore W2044658510C109523444 @default.
- W2044658510 hasConceptScore W2044658510C126322002 @default.
- W2044658510 hasConceptScore W2044658510C153911025 @default.
- W2044658510 hasConceptScore W2044658510C181199279 @default.
- W2044658510 hasConceptScore W2044658510C185592680 @default.
- W2044658510 hasConceptScore W2044658510C186738567 @default.
- W2044658510 hasConceptScore W2044658510C189165786 @default.
- W2044658510 hasConceptScore W2044658510C2775958869 @default.
- W2044658510 hasConceptScore W2044658510C2775965246 @default.
- W2044658510 hasConceptScore W2044658510C2776414213 @default.
- W2044658510 hasConceptScore W2044658510C2776747403 @default.
- W2044658510 hasConceptScore W2044658510C2777151630 @default.
- W2044658510 hasConceptScore W2044658510C2778382381 @default.
- W2044658510 hasConceptScore W2044658510C2778394429 @default.
- W2044658510 hasConceptScore W2044658510C28406088 @default.
- W2044658510 hasConceptScore W2044658510C55493867 @default.
- W2044658510 hasConceptScore W2044658510C55728118 @default.
- W2044658510 hasConceptScore W2044658510C71829478 @default.
- W2044658510 hasConceptScore W2044658510C71924100 @default.
- W2044658510 hasConceptScore W2044658510C85265743 @default.
- W2044658510 hasConceptScore W2044658510C86803240 @default.
- W2044658510 hasConceptScore W2044658510C95444343 @default.
- W2044658510 hasIssue "3" @default.
- W2044658510 hasLocation W20446585101 @default.
- W2044658510 hasLocation W20446585102 @default.
- W2044658510 hasOpenAccess W2044658510 @default.
- W2044658510 hasPrimaryLocation W20446585101 @default.
- W2044658510 hasRelatedWork W1981148477 @default.
- W2044658510 hasRelatedWork W2044658510 @default.
- W2044658510 hasRelatedWork W2045946354 @default.
- W2044658510 hasRelatedWork W2048024952 @default.
- W2044658510 hasRelatedWork W2061992885 @default.
- W2044658510 hasRelatedWork W2077226313 @default.
- W2044658510 hasRelatedWork W2251576921 @default.
- W2044658510 hasRelatedWork W2412516833 @default.
- W2044658510 hasRelatedWork W2467125698 @default.
- W2044658510 hasRelatedWork W4285321171 @default.
- W2044658510 hasVolume "1621" @default.
- W2044658510 isParatext "false" @default.
- W2044658510 isRetracted "false" @default.
- W2044658510 magId "2044658510" @default.
- W2044658510 workType "article" @default.