FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044659008> ?p ?o ?g. }

• W2044659008 endingPage "256" @default.
• W2044659008 startingPage "246" @default.
• W2044659008 abstract "Clinical data has shown that stroke exacerbates dementia in Alzheimer's disease (AD) patients. Previous work, combining rat models of AD and stroke have shown that neuroinflammation may be the common mediator between AD and stroke toxicity. This study examined the effects of triflusal (2-acetoxy-4-trifluoromethylbenzoic acid) in APP23 transgenic mice receiving strokes. Six month-old APP23 mice over-expressing mutant human amyloid precursor protein (APP) were used to model AD in this study. Unilateral injections of a potent vasoconstrictor, endothelin-1, into the striatum were used to mimic small lacunar infarcts. Immunohistochemical analysis was performed to examine AD-like pathology and inflammatory correlates of stroke and AD. APP23 mice showed increases in AD-like pathology and inflammatory markers of AD in the cortex and hippocampus. Endothelin-induced ischemia triggered an inflammatory response along with increases in AD pathological markers in the region of the infarct. Triflusal reduced inflammation surrounding the endothelin-induced infarct only. At the dose used, anti-inflammatory treatment may be beneficial in reducing the AD and inflammatory correlates of stroke in a combined AD-stroke mouse model." @default.
• W2044659008 created "2016-06-24" @default.
• W2044659008 creator A5031476350 @default.
• W2044659008 creator A5039754223 @default.
• W2044659008 creator A5059300906 @default.
• W2044659008 creator A5063004788 @default.
• W2044659008 creator A5066465053 @default.
• W2044659008 creator A5077095217 @default.
• W2044659008 creator A5082852366 @default.
• W2044659008 date "2010-12-01" @default.
• W2044659008 modified "2023-10-17" @default.
• W2044659008 title "Triflusal reduces cerebral ischemia induced inflammation in a combined mouse model of Alzheimer's disease and stroke" @default.
• W2044659008 cites W1500754494 @default.
• W2044659008 cites W1918909705 @default.
• W2044659008 cites W1972784541 @default.
• W2044659008 cites W1978105781 @default.
• W2044659008 cites W1983670592 @default.
• W2044659008 cites W1986115629 @default.
• W2044659008 cites W1987882483 @default.
• W2044659008 cites W2008092392 @default.
• W2044659008 cites W2032386882 @default.
• W2044659008 cites W2051134431 @default.
• W2044659008 cites W2085431369 @default.
• W2044659008 cites W2090930997 @default.
• W2044659008 cites W2103861118 @default.
• W2044659008 cites W2126793161 @default.
• W2044659008 cites W2128171829 @default.
• W2044659008 cites W2135612359 @default.
• W2044659008 cites W2144212564 @default.
• W2044659008 cites W2171583866 @default.
• W2044659008 cites W3190419098 @default.
• W2044659008 cites W4296588155 @default.
• W2044659008 cites W78443299 @default.
• W2044659008 doi "https://doi.org/10.1016/j.brainres.2010.10.008" @default.
• W2044659008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20934412" @default.
• W2044659008 hasPublicationYear "2010" @default.
• W2044659008 type Work @default.
• W2044659008 sameAs 2044659008 @default.
• W2044659008 citedByCount "22" @default.
• W2044659008 countsByYear W20446590082012 @default.
• W2044659008 countsByYear W20446590082013 @default.
• W2044659008 countsByYear W20446590082014 @default.
• W2044659008 countsByYear W20446590082015 @default.
• W2044659008 countsByYear W20446590082017 @default.
• W2044659008 countsByYear W20446590082018 @default.
• W2044659008 countsByYear W20446590082020 @default.
• W2044659008 countsByYear W20446590082021 @default.
• W2044659008 countsByYear W20446590082022 @default.
• W2044659008 countsByYear W20446590082023 @default.
• W2044659008 crossrefType "journal-article" @default.
• W2044659008 hasAuthorship W2044659008A5031476350 @default.
• W2044659008 hasAuthorship W2044659008A5039754223 @default.
• W2044659008 hasAuthorship W2044659008A5059300906 @default.
• W2044659008 hasAuthorship W2044659008A5063004788 @default.
• W2044659008 hasAuthorship W2044659008A5066465053 @default.
• W2044659008 hasAuthorship W2044659008A5077095217 @default.
• W2044659008 hasAuthorship W2044659008A5082852366 @default.
• W2044659008 hasConcept C102230213 @default.
• W2044659008 hasConcept C104317684 @default.
• W2044659008 hasConcept C126322002 @default.
• W2044659008 hasConcept C127413603 @default.
• W2044659008 hasConcept C141035611 @default.
• W2044659008 hasConcept C142724271 @default.
• W2044659008 hasConcept C2776914184 @default.
• W2044659008 hasConcept C2777952318 @default.
• W2044659008 hasConcept C2778820722 @default.
• W2044659008 hasConcept C2779134260 @default.
• W2044659008 hasConcept C2779483572 @default.
• W2044659008 hasConcept C2780645631 @default.
• W2044659008 hasConcept C2781161787 @default.
• W2044659008 hasConcept C502032728 @default.
• W2044659008 hasConcept C541997718 @default.
• W2044659008 hasConcept C55493867 @default.
• W2044659008 hasConcept C71924100 @default.
• W2044659008 hasConcept C78519656 @default.
• W2044659008 hasConcept C86803240 @default.
• W2044659008 hasConcept C87753298 @default.
• W2044659008 hasConceptScore W2044659008C102230213 @default.
• W2044659008 hasConceptScore W2044659008C104317684 @default.
• W2044659008 hasConceptScore W2044659008C126322002 @default.
• W2044659008 hasConceptScore W2044659008C127413603 @default.
• W2044659008 hasConceptScore W2044659008C141035611 @default.
• W2044659008 hasConceptScore W2044659008C142724271 @default.
• W2044659008 hasConceptScore W2044659008C2776914184 @default.
• W2044659008 hasConceptScore W2044659008C2777952318 @default.
• W2044659008 hasConceptScore W2044659008C2778820722 @default.
• W2044659008 hasConceptScore W2044659008C2779134260 @default.
• W2044659008 hasConceptScore W2044659008C2779483572 @default.
• W2044659008 hasConceptScore W2044659008C2780645631 @default.
• W2044659008 hasConceptScore W2044659008C2781161787 @default.
• W2044659008 hasConceptScore W2044659008C502032728 @default.
• W2044659008 hasConceptScore W2044659008C541997718 @default.
• W2044659008 hasConceptScore W2044659008C55493867 @default.
• W2044659008 hasConceptScore W2044659008C71924100 @default.
• W2044659008 hasConceptScore W2044659008C78519656 @default.
• W2044659008 hasConceptScore W2044659008C86803240 @default.
• W2044659008 hasConceptScore W2044659008C87753298 @default.
• W2044659008 hasLocation W20446590081 @default.

• next