Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044664579> ?p ?o ?g. }
- W2044664579 endingPage "225" @default.
- W2044664579 startingPage "219" @default.
- W2044664579 abstract "A monoclonal antibody was produced against purified nidogen extracted from a mouse basement-membrane-producing tumor. This antibody reacted with a determinant on Nd-40, a rod which separates the globular domains of nidogen. Antigenicity depends on intrachain disulfide bonds within this rod. The monoclonal antibody was used to detect nidogen fragments after proteolytic cleavage of isolated nidogen, and nidogen complexed to laminin. The data indicate that thrombin and thermolysin generated very different patterns of degradation, but in both cases no differences were found between isolated and complexed nidogen. In contrast, nidogen in the laminin-nidogen complex was much less degraded by trypsin than isolated nidogen, indicating that an interaction between these basement membrane components reduces the susceptibility of nidogen to trypsin digestion. Immunofluorescent studies, using the monoclonal antibody on sections of the EHS tumor after proteolytic digestion, showed that the retention or disappearance of the Nd-40 determinant correlated with the in vitro digestion pattern of the laminin-nidogen complex." @default.
- W2044664579 created "2016-06-24" @default.
- W2044664579 creator A5010516486 @default.
- W2044664579 creator A5020541683 @default.
- W2044664579 creator A5024125070 @default.
- W2044664579 creator A5058024376 @default.
- W2044664579 creator A5089801877 @default.
- W2044664579 date "1988-02-01" @default.
- W2044664579 modified "2023-10-18" @default.
- W2044664579 title "Analysis of degradation of the basement membrane protein nidogen, using a specific monoclonal antibody" @default.
- W2044664579 cites W1492098854 @default.
- W2044664579 cites W1492689761 @default.
- W2044664579 cites W1504662248 @default.
- W2044664579 cites W1549719435 @default.
- W2044664579 cites W1561047920 @default.
- W2044664579 cites W1580661757 @default.
- W2044664579 cites W1604993705 @default.
- W2044664579 cites W1628719417 @default.
- W2044664579 cites W1956408130 @default.
- W2044664579 cites W1964394713 @default.
- W2044664579 cites W1964555681 @default.
- W2044664579 cites W1984532185 @default.
- W2044664579 cites W1987295447 @default.
- W2044664579 cites W1992872448 @default.
- W2044664579 cites W1995493762 @default.
- W2044664579 cites W2008553112 @default.
- W2044664579 cites W2014043577 @default.
- W2044664579 cites W2017380929 @default.
- W2044664579 cites W2022797781 @default.
- W2044664579 cites W2028256138 @default.
- W2044664579 cites W2030522563 @default.
- W2044664579 cites W2034244905 @default.
- W2044664579 cites W2041918518 @default.
- W2044664579 cites W2043795458 @default.
- W2044664579 cites W2053612392 @default.
- W2044664579 cites W2062954964 @default.
- W2044664579 cites W2067335951 @default.
- W2044664579 cites W2083790449 @default.
- W2044664579 cites W2087737282 @default.
- W2044664579 cites W2100837269 @default.
- W2044664579 cites W2101314615 @default.
- W2044664579 cites W2154463760 @default.
- W2044664579 cites W2170424061 @default.
- W2044664579 cites W2234806955 @default.
- W2044664579 cites W2408084798 @default.
- W2044664579 cites W269351737 @default.
- W2044664579 doi "https://doi.org/10.1111/j.1432-1033.1988.tb13876.x" @default.
- W2044664579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3126070" @default.
- W2044664579 hasPublicationYear "1988" @default.
- W2044664579 type Work @default.
- W2044664579 sameAs 2044664579 @default.
- W2044664579 citedByCount "35" @default.
- W2044664579 countsByYear W20446645792012 @default.
- W2044664579 countsByYear W20446645792020 @default.
- W2044664579 crossrefType "journal-article" @default.
- W2044664579 hasAuthorship W2044664579A5010516486 @default.
- W2044664579 hasAuthorship W2044664579A5020541683 @default.
- W2044664579 hasAuthorship W2044664579A5024125070 @default.
- W2044664579 hasAuthorship W2044664579A5058024376 @default.
- W2044664579 hasAuthorship W2044664579A5089801877 @default.
- W2044664579 hasConcept C153911025 @default.
- W2044664579 hasConcept C159654299 @default.
- W2044664579 hasConcept C181199279 @default.
- W2044664579 hasConcept C185020521 @default.
- W2044664579 hasConcept C185592680 @default.
- W2044664579 hasConcept C189165786 @default.
- W2044664579 hasConcept C203014093 @default.
- W2044664579 hasConcept C2776193487 @default.
- W2044664579 hasConcept C2779026604 @default.
- W2044664579 hasConcept C2779814568 @default.
- W2044664579 hasConcept C2780340462 @default.
- W2044664579 hasConcept C542903549 @default.
- W2044664579 hasConcept C55493867 @default.
- W2044664579 hasConcept C86803240 @default.
- W2044664579 hasConcept C95444343 @default.
- W2044664579 hasConceptScore W2044664579C153911025 @default.
- W2044664579 hasConceptScore W2044664579C159654299 @default.
- W2044664579 hasConceptScore W2044664579C181199279 @default.
- W2044664579 hasConceptScore W2044664579C185020521 @default.
- W2044664579 hasConceptScore W2044664579C185592680 @default.
- W2044664579 hasConceptScore W2044664579C189165786 @default.
- W2044664579 hasConceptScore W2044664579C203014093 @default.
- W2044664579 hasConceptScore W2044664579C2776193487 @default.
- W2044664579 hasConceptScore W2044664579C2779026604 @default.
- W2044664579 hasConceptScore W2044664579C2779814568 @default.
- W2044664579 hasConceptScore W2044664579C2780340462 @default.
- W2044664579 hasConceptScore W2044664579C542903549 @default.
- W2044664579 hasConceptScore W2044664579C55493867 @default.
- W2044664579 hasConceptScore W2044664579C86803240 @default.
- W2044664579 hasConceptScore W2044664579C95444343 @default.
- W2044664579 hasIssue "1" @default.
- W2044664579 hasLocation W20446645791 @default.
- W2044664579 hasLocation W20446645792 @default.
- W2044664579 hasOpenAccess W2044664579 @default.
- W2044664579 hasPrimaryLocation W20446645791 @default.
- W2044664579 hasRelatedWork W1964555681 @default.
- W2044664579 hasRelatedWork W1981056738 @default.
- W2044664579 hasRelatedWork W2037509311 @default.