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- W2044665464 abstract "Most of the neurons and macroglial cells in the vertebrate CNS are thought to develop from the neuroepithelial cells that form the neural tube. But what are the lineage relationships between the different types of cells in the CNS? Also, what determines whether an individual neuroepithelial cell develops into a particular type of neuron or glial cell, and when are these decisions made? Questions about cell lineage and determination are difficult to answer unambiguously in vertebrates, especially in the mammalian CNS, where the combined problems of complexity, cell identification and inaccessibility have impeded progress. We have combined several strategies to circumvent these problems in our attempt to determine the lineage relationships between the two main types of macroglial cells — astrocytes and oligodendrocytes." @default.
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- W2044665464 date "1984-12-01" @default.
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- W2044665464 title "Glial cell development in the rat optic nerve" @default.
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- W2044665464 doi "https://doi.org/10.1016/s0166-2236(84)80257-x" @default.
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