Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044665821> ?p ?o ?g. }
- W2044665821 endingPage "969" @default.
- W2044665821 startingPage "957" @default.
- W2044665821 abstract "Eukaryotic organisms have quality-control mechanisms that allow misfolded or unassembled proteins to be retained in the endoplasmic reticulum (ER) and subsequently degraded by ER-associated degradation (ERAD). The ERAD pathway is well studied in yeast and mammals; however, the biological functions of plant ERAD have not been reported. Through molecular and cellular biological approaches, we found that ERAD is necessary for plants to overcome salt stress. Upon salt treatment ubiquitinated proteins increased in plant cells, especially unfolded proteins that quickly accumulated in the ER and subsequently induced ER stress responses. Defect in HRD3A of the HRD1/HRD3 complex of the ERAD pathway resulted in alteration of the unfolded protein response (UPR), increased plant sensitivity to salt, and retention of ERAD substrates in plant cells. Furthermore, we demonstrated that Ca2+ release from the ER is involved in the elevation of UPR and reactive oxygen species (ROS) participates the ERAD-related plant salt response pathway." @default.
- W2044665821 created "2016-06-24" @default.
- W2044665821 creator A5002288609 @default.
- W2044665821 creator A5007127959 @default.
- W2044665821 creator A5040279592 @default.
- W2044665821 creator A5070737489 @default.
- W2044665821 creator A5073838880 @default.
- W2044665821 creator A5075408325 @default.
- W2044665821 creator A5079928312 @default.
- W2044665821 creator A5088815104 @default.
- W2044665821 creator A5089666742 @default.
- W2044665821 creator A5090062650 @default.
- W2044665821 date "2010-12-28" @default.
- W2044665821 modified "2023-10-18" @default.
- W2044665821 title "The endoplasmic reticulum-associated degradation is necessary for plant salt tolerance" @default.
- W2044665821 cites W1524893958 @default.
- W2044665821 cites W1536902696 @default.
- W2044665821 cites W1782287000 @default.
- W2044665821 cites W1972334626 @default.
- W2044665821 cites W1973824858 @default.
- W2044665821 cites W1979146391 @default.
- W2044665821 cites W1981551685 @default.
- W2044665821 cites W1984094759 @default.
- W2044665821 cites W1986698508 @default.
- W2044665821 cites W1999763554 @default.
- W2044665821 cites W2001856591 @default.
- W2044665821 cites W2004953284 @default.
- W2044665821 cites W2006196684 @default.
- W2044665821 cites W2007422965 @default.
- W2044665821 cites W2025545161 @default.
- W2044665821 cites W2029392687 @default.
- W2044665821 cites W2032379590 @default.
- W2044665821 cites W2048968219 @default.
- W2044665821 cites W2052821301 @default.
- W2044665821 cites W2056689556 @default.
- W2044665821 cites W2057106493 @default.
- W2044665821 cites W2059586921 @default.
- W2044665821 cites W2071247960 @default.
- W2044665821 cites W2081104776 @default.
- W2044665821 cites W2093210658 @default.
- W2044665821 cites W2093837580 @default.
- W2044665821 cites W2095239764 @default.
- W2044665821 cites W2099491608 @default.
- W2044665821 cites W2104362188 @default.
- W2044665821 cites W2104659028 @default.
- W2044665821 cites W2105162027 @default.
- W2044665821 cites W2111270598 @default.
- W2044665821 cites W2113298484 @default.
- W2044665821 cites W2116752345 @default.
- W2044665821 cites W2124338693 @default.
- W2044665821 cites W2128770167 @default.
- W2044665821 cites W2129355294 @default.
- W2044665821 cites W2130273068 @default.
- W2044665821 cites W2134073995 @default.
- W2044665821 cites W2135513925 @default.
- W2044665821 cites W2137059930 @default.
- W2044665821 cites W2137662702 @default.
- W2044665821 cites W2139328007 @default.
- W2044665821 cites W2139577310 @default.
- W2044665821 cites W2140612665 @default.
- W2044665821 cites W2141389812 @default.
- W2044665821 cites W2146548897 @default.
- W2044665821 cites W2152398979 @default.
- W2044665821 cites W2168195126 @default.
- W2044665821 cites W2170604154 @default.
- W2044665821 cites W2171520973 @default.
- W2044665821 cites W4230336193 @default.
- W2044665821 doi "https://doi.org/10.1038/cr.2010.181" @default.
- W2044665821 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3203697" @default.
- W2044665821 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21187857" @default.
- W2044665821 hasPublicationYear "2010" @default.
- W2044665821 type Work @default.
- W2044665821 sameAs 2044665821 @default.
- W2044665821 citedByCount "126" @default.
- W2044665821 countsByYear W20446658212012 @default.
- W2044665821 countsByYear W20446658212013 @default.
- W2044665821 countsByYear W20446658212014 @default.
- W2044665821 countsByYear W20446658212015 @default.
- W2044665821 countsByYear W20446658212016 @default.
- W2044665821 countsByYear W20446658212017 @default.
- W2044665821 countsByYear W20446658212018 @default.
- W2044665821 countsByYear W20446658212019 @default.
- W2044665821 countsByYear W20446658212020 @default.
- W2044665821 countsByYear W20446658212021 @default.
- W2044665821 countsByYear W20446658212022 @default.
- W2044665821 countsByYear W20446658212023 @default.
- W2044665821 crossrefType "journal-article" @default.
- W2044665821 hasAuthorship W2044665821A5002288609 @default.
- W2044665821 hasAuthorship W2044665821A5007127959 @default.
- W2044665821 hasAuthorship W2044665821A5040279592 @default.
- W2044665821 hasAuthorship W2044665821A5070737489 @default.
- W2044665821 hasAuthorship W2044665821A5073838880 @default.
- W2044665821 hasAuthorship W2044665821A5075408325 @default.
- W2044665821 hasAuthorship W2044665821A5079928312 @default.
- W2044665821 hasAuthorship W2044665821A5088815104 @default.
- W2044665821 hasAuthorship W2044665821A5089666742 @default.
- W2044665821 hasAuthorship W2044665821A5090062650 @default.
- W2044665821 hasBestOaLocation W20446658211 @default.