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- W2044676118 abstract "Cade's discovery of lithium's antimanic effect soon became known in Europe and was confirmed by a Danish controlled trial. The same investigators discovered a prophylactic action of lithium against both manic and depressive recurrences, which was confirmed by a Swiss-Czech-Danish cooperative trial. The evidence of these studies was met with skepticism based on methodological speculations, but a Danish randomised, placebo-controlled, double-blind trial of discontinuation design established the prophylactic action of lithium, as did a number of European controlled trials of start design and discontinuation design. The review ends with personal memories of John Cade." @default.
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- W2044676118 date "1999-12-01" @default.
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- W2044676118 title "The early European lithium studies" @default.
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- W2044676118 doi "https://doi.org/10.1111/j.1440-1614.1999.00667.x" @default.
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