FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044697701> ?p ?o ?g. }

• W2044697701 endingPage "1544" @default.
• W2044697701 startingPage "1537" @default.
• W2044697701 abstract "Some phosphorothioate oligonucleotides have been shown previously to stimulate cell proliferation and immunoglobulin production. In the current study, we examined the effects of cyclodextrin analogs as immunomodulatory agents for oligonucleotide-induced immune stimulation, both in vitro and in vivo. Incubation of splenocytes with a 27-mer phosphorothioate oligonucleotide that induces immune stimulation increased cell proliferation as measured by [3H]thymidine incorporation, whereas treatment of splenocytes with the phosphorothioate oligonucleotide complexed to cyclodextrin analogs markedly reduced oligonucleotide-induced cell proliferation. Similarly, administration of the 27-mer phosphorothioate oligonucleotide into mice resulted in splenomegaly and an increase in IgM production 48 hr post-administration. Administration of the oligonucleotide along with cyclodextrin analogs resulted in a significant suppression of splenomegaly and IgM response. Such suppression was dependent on the concentration of cyclodextrin analogs and was observed with various other immune stimulatory phosphorothioate oligonucleotide sequences. Administration of cyclodextrin analogs alone had no effect on splenomegaly or immune stimulation." @default.
• W2044697701 created "2016-06-24" @default.
• W2044697701 creator A5017047667 @default.
• W2044697701 creator A5022084947 @default.
• W2044697701 creator A5038738832 @default.
• W2044697701 creator A5069014764 @default.
• W2044697701 date "1996-11-01" @default.
• W2044697701 modified "2023-10-17" @default.
• W2044697701 title "Modulation of oligonucleotide-induced immune stimulation by cyclodextrin analogs" @default.
• W2044697701 cites W1199216903 @default.
• W2044697701 cites W1447077155 @default.
• W2044697701 cites W1670899815 @default.
• W2044697701 cites W1972147130 @default.
• W2044697701 cites W1975256590 @default.
• W2044697701 cites W1984400882 @default.
• W2044697701 cites W1986616196 @default.
• W2044697701 cites W1995118424 @default.
• W2044697701 cites W2009593695 @default.
• W2044697701 cites W2028143440 @default.
• W2044697701 cites W2036746674 @default.
• W2044697701 cites W2042017272 @default.
• W2044697701 cites W2047366876 @default.
• W2044697701 cites W2050014764 @default.
• W2044697701 cites W2082582589 @default.
• W2044697701 cites W2088348110 @default.
• W2044697701 cites W2090819044 @default.
• W2044697701 cites W2115177369 @default.
• W2044697701 cites W284913300 @default.
• W2044697701 cites W39461992 @default.
• W2044697701 cites W47464580 @default.
• W2044697701 doi "https://doi.org/10.1016/s0006-2952(96)00555-2" @default.
• W2044697701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8937468" @default.
• W2044697701 hasPublicationYear "1996" @default.
• W2044697701 type Work @default.
• W2044697701 sameAs 2044697701 @default.
• W2044697701 citedByCount "19" @default.
• W2044697701 countsByYear W20446977012014 @default.
• W2044697701 countsByYear W20446977012015 @default.
• W2044697701 countsByYear W20446977012018 @default.
• W2044697701 countsByYear W20446977012023 @default.
• W2044697701 crossrefType "journal-article" @default.
• W2044697701 hasAuthorship W2044697701A5017047667 @default.
• W2044697701 hasAuthorship W2044697701A5022084947 @default.
• W2044697701 hasAuthorship W2044697701A5038738832 @default.
• W2044697701 hasAuthorship W2044697701A5069014764 @default.
• W2044697701 hasConcept C129312508 @default.
• W2044697701 hasConcept C134018914 @default.
• W2044697701 hasConcept C150903083 @default.
• W2044697701 hasConcept C153911025 @default.
• W2044697701 hasConcept C185592680 @default.
• W2044697701 hasConcept C189976730 @default.
• W2044697701 hasConcept C202751555 @default.
• W2044697701 hasConcept C203014093 @default.
• W2044697701 hasConcept C207001950 @default.
• W2044697701 hasConcept C24998067 @default.
• W2044697701 hasConcept C2777108182 @default.
• W2044697701 hasConcept C2779433975 @default.
• W2044697701 hasConcept C552990157 @default.
• W2044697701 hasConcept C55493867 @default.
• W2044697701 hasConcept C62112901 @default.
• W2044697701 hasConcept C86803240 @default.
• W2044697701 hasConcept C8891405 @default.
• W2044697701 hasConcept C98274493 @default.
• W2044697701 hasConceptScore W2044697701C129312508 @default.
• W2044697701 hasConceptScore W2044697701C134018914 @default.
• W2044697701 hasConceptScore W2044697701C150903083 @default.
• W2044697701 hasConceptScore W2044697701C153911025 @default.
• W2044697701 hasConceptScore W2044697701C185592680 @default.
• W2044697701 hasConceptScore W2044697701C189976730 @default.
• W2044697701 hasConceptScore W2044697701C202751555 @default.
• W2044697701 hasConceptScore W2044697701C203014093 @default.
• W2044697701 hasConceptScore W2044697701C207001950 @default.
• W2044697701 hasConceptScore W2044697701C24998067 @default.
• W2044697701 hasConceptScore W2044697701C2777108182 @default.
• W2044697701 hasConceptScore W2044697701C2779433975 @default.
• W2044697701 hasConceptScore W2044697701C552990157 @default.
• W2044697701 hasConceptScore W2044697701C55493867 @default.
• W2044697701 hasConceptScore W2044697701C62112901 @default.
• W2044697701 hasConceptScore W2044697701C86803240 @default.
• W2044697701 hasConceptScore W2044697701C8891405 @default.
• W2044697701 hasConceptScore W2044697701C98274493 @default.
• W2044697701 hasIssue "10" @default.
• W2044697701 hasLocation W20446977011 @default.
• W2044697701 hasLocation W20446977012 @default.
• W2044697701 hasOpenAccess W2044697701 @default.
• W2044697701 hasPrimaryLocation W20446977011 @default.
• W2044697701 hasRelatedWork W1970057212 @default.
• W2044697701 hasRelatedWork W1971274279 @default.
• W2044697701 hasRelatedWork W1985693107 @default.
• W2044697701 hasRelatedWork W2005076303 @default.
• W2044697701 hasRelatedWork W2057712953 @default.
• W2044697701 hasRelatedWork W2119506352 @default.
• W2044697701 hasRelatedWork W2362675350 @default.
• W2044697701 hasRelatedWork W2364406978 @default.
• W2044697701 hasRelatedWork W2371628387 @default.
• W2044697701 hasRelatedWork W2401172966 @default.
• W2044697701 hasVolume "52" @default.
• W2044697701 isParatext "false" @default.

• next