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- W2044729150 abstract "Nasal airway resistance and nasal symptoms were evaluated in patients with perennial non-allergic rhinitis before and after vasoconstrictory drugs and placebo taken orally. The patients were partly selected; these suffering mainly from nasal obstruction being tested. Phenylpropanolamine (PPA) in a dose of 100 nig in a sustained-release preparation clearly decreased the nasal airway resistance measured rhimomanometrically. PPA in a dose of 50 mg and combined with au antihistamine had no obvious decongesting effect. Placebo and dihydroergotamine (DHE) in a dose of 5 mg did not decrease the nasal airway resistance. PPA (100 mg) and the combined preparation containing PPA in the lower dose (50 mg) taken twice a day in across-over, double-blind study significantly reduced nasal obstruction, secretion, and sneezing compared with placebo. Side effects of PPA are discussed." @default.
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- W2044729150 date "1982-02-01" @default.
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- W2044729150 title "Oral Vasoconstrictors in Perennial Non-Allergic Rhinitis" @default.
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- W2044729150 doi "https://doi.org/10.1111/j.1398-9995.1982.tb01879.x" @default.
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