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- W2044745660 abstract "AbstractAmoxicillin sodium salt degradation in solid state relies on a sequential reaction consisting of two pseudo-first-order processes. Amoxicillin trihydrate, now used in pharmaceutical formulations, is significantly more stable than sodium amoxicillin. It degrades according to Prout-Tompkins model. We studied the stability of amoxicillin at temperatures of 37°, 50°, 80°, 90°, 100° y 110° C. HPLC was chosen as the analytical method. Amoxicillin and its decomposition products are separated by reversed-phase (C18) HPLC with gradient elution." @default.
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- W2044745660 date "1989-01-01" @default.
- W2044745660 modified "2023-09-27" @default.
- W2044745660 title "Study on the rate of decomposition of amoxicillin in solid state using high-performance liquid chromatography" @default.
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- W2044745660 doi "https://doi.org/10.3109/03639048909043676" @default.
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