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- W2044762445 abstract "Struma ovarii is an uncommon teratoma of the ovary that contains over 50% of thyroid tissue. This tumor accounts for 0.2-1.3% of all ovarian tumors and for 2-4% of all teratomas. Malignancy is reported in 5% to 37% of patients with struma ovarii, with metastases occurring in few cases. 1—3 This article reports a patient with some unusual features, including malignancy, metastases, hormone production, and a fatal outcome. Literature is reviewed, and significance of appropriate treatment and follow-up of these patients is emphasized. A 38-year-old woman was referred to our hospital in 1994 for a second opinion regarding management of a struma ovarii. The disease had been diagnosed at another center in 1981, when she was 25 years old, after right salpingectomy and partial oophorectomy for a right ovarian cyst. At that time, pathological study showed a struma ovarii with no signs of malignancy. In 1993 (at the age of 37 years), patient underwent a left salpingo-oophorectomy and completion of right oophorectomy because of detection of an 8-cm left ovarian mass. Multiple peritoneal nodules were found during surgery, and pathological study found a struma ovarii with positive immunohistochemistry for thyroglobulin. A 131 I scan revealed physiological accumulation of iodine in the thyroid gland and pathological deposits in abdomen. Total thyroidectomy and 131 I ablation therapy were proposed, but the" @default.
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- W2044762445 date "2011-08-01" @default.
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- W2044762445 title "Unusual characteristics and fatal outcome of a malignant struma ovarii. Case report and literature review" @default.
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- W2044762445 doi "https://doi.org/10.1016/j.endonu.2011.02.011" @default.
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