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• W2044768013 abstract "Serotonin (5-HT) immunocytochemistry was used at the electron microscopic level to characterize the ultrastructural features of 5-HT axon terminals (varicosities) hyperinnervating the neostriatum of adult rats, 3 months after a neonatal destruction of the nigrostriatal dopamine system by intraventricular 6-hydroxydopamine. 5-HT-immunostained terminals from the anterior half of the hyperinnervated neostriatum were examined in single thin sections, and compared to their counterparts in vehicle-injected controls with respect to shape, size, organelle content, presence of a synaptic membrane differentiation and composition of the microenvironment. The intrinsic and relational features of the 5-HT-immunostained varicosities were essentially the same in 5-HT-hyperinnervated and control tissue. In particular, the frequency with which these varicosities made synaptic contacts was similarly low in both conditions (6-8% for whole varicosities), as already described in normal adult rat neostriatum. The distributional frequency of elements juxtaposed to the 5-HT-immunostained varicosities was also comparable in control and 5-HT-hyperinnervated tissue. However, in both conditions, there were much fewer dendritic spines in the microenvironment of 5-HT varicosities than around unlabeled terminals randomly selected from the same thin sections. This difference seemed entirely due to the numerous axo-spinous synaptic contacts made by the randomly selected, unlabeled varicosities. Together with recent observations on the 5-HT-hyperinnervation of adult rat hippocampus after grafts of fetal neurons, these data lead to the suggestion that mostly non-junctional neostriatal 5-HT terminals are not committed to a specific intratissular microenvironment. This might in part explain why they grow in excess when reinnervating adult tissue after a lesion or a graft." @default.
• W2044768013 created "2016-06-24" @default.
• W2044768013 creator A5002953056 @default.
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• W2044768013 date "1992-01-01" @default.
• W2044768013 modified "2023-10-03" @default.
• W2044768013 title "Ultrastructural analysis of the serotonin hyperinnervation in adult rat neostriatum following neonatal dopamine denervation with 6-hydroxydopamine" @default.
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• W2044768013 cites W1970338199 @default.
• W2044768013 cites W1970820931 @default.
• W2044768013 cites W1970979709 @default.
• W2044768013 cites W1979394627 @default.
• W2044768013 cites W1980093205 @default.
• W2044768013 cites W1980501557 @default.
• W2044768013 cites W1980518117 @default.
• W2044768013 cites W1981522667 @default.
• W2044768013 cites W1991507034 @default.
• W2044768013 cites W1992130233 @default.
• W2044768013 cites W1992437071 @default.
• W2044768013 cites W1993444428 @default.
• W2044768013 cites W1993609355 @default.
• W2044768013 cites W1993899300 @default.
• W2044768013 cites W1994410954 @default.
• W2044768013 cites W1996916011 @default.
• W2044768013 cites W1998689450 @default.
• W2044768013 cites W2000522290 @default.
• W2044768013 cites W2001181389 @default.
• W2044768013 cites W2002932967 @default.
• W2044768013 cites W2004605002 @default.
• W2044768013 cites W2008097494 @default.
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• W2044768013 cites W2026381642 @default.
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• W2044768013 cites W2036288412 @default.
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• W2044768013 cites W2037607405 @default.
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• W2044768013 cites W2039732315 @default.
• W2044768013 cites W2042990377 @default.
• W2044768013 cites W2045236704 @default.
• W2044768013 cites W2050426362 @default.
• W2044768013 cites W2050976425 @default.
• W2044768013 cites W2054265484 @default.
• W2044768013 cites W2056677349 @default.
• W2044768013 cites W2063072517 @default.
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• W2044768013 doi "https://doi.org/10.1016/0006-8993(92)90363-e" @default.
• W2044768013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1611468" @default.
• W2044768013 hasPublicationYear "1992" @default.
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