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- W2044777748 abstract "Creatine kinase (CK) was shown to be present in numerous kinds of animals (Ennor, 1961; Kuby et al., 1962). The enzyme was found mainly in muscular, electric and nervous organs. But until now no data were available on the intracellular distribution of CK in these organs. During studies concerning P32 incorporation into isolated pigeon breast mitochondria we observed P32 labelling of creatine phosphate. By filtering centrifugation it was demonstrated that the observed creatine phosphate was actually formed inside the mitochondria (Heldt, 1962). In studies on fractionated enzyme extraction of rat heart and pigeon breast muscle homogenates Pette and Luh found the occurrence of CK in the fraction of mitochondrial enzymes (Pette and Luh, unpublished, 1962). But it was not established that CK was really part of the mitochondria. In this paper it is shown that high levels of CK are contained in isolated mitochondria controlled for the absence of cytoplasmic contamination." @default.
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- W2044777748 date "1964-08-01" @default.
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- W2044777748 title "High activity of creatine kinase in mitochondria from muscle and brain and evidence for a separate mitochondrial isoenzyme of creatine kinase" @default.
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- W2044777748 doi "https://doi.org/10.1016/0006-291x(64)90185-8" @default.
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