FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044777781> ?p ?o ?g. }

• W2044777781 endingPage "663" @default.
• W2044777781 startingPage "656" @default.
• W2044777781 abstract "Abstract Presently, the zebrafish is the only vertebrate model compatible with contemporary paradigms of drug discovery. Zebrafish embryos are amenable to automation necessary for high‐throughput chemical screens, and optical transparency makes them potentially suited for image‐based screening. However, the lack of tools for automated analysis of complex images presents an obstacle to using the zebrafish as a high‐throughput screening model. We have developed an automated system for imaging and analyzing zebrafish embryos in multi‐well plates regardless of embryo orientation and without user intervention. Images of fluorescent embryos were acquired on a high‐content reader and analyzed using an artificial intelligence‐based image analysis method termed Cognition Network Technology (CNT). CNT reliably detected transgenic fluorescent embryos ( Tg(fli1:EGFP) y1 ) arrayed in 96‐well plates and quantified intersegmental blood vessel development in embryos treated with small molecule inhibitors of anigiogenesis. The results demonstrate it is feasible to adapt image‐based high‐content screening methodology to measure complex whole organism phenotypes. Developmental Dynamics 238:656–663, 2009. © 2009 Wiley‐Liss, Inc." @default.
• W2044777781 created "2016-06-24" @default.
• W2044777781 creator A5018254555 @default.
• W2044777781 creator A5035575101 @default.
• W2044777781 creator A5038463777 @default.
• W2044777781 creator A5045341517 @default.
• W2044777781 creator A5059505159 @default.
• W2044777781 creator A5085858115 @default.
• W2044777781 creator A5087527556 @default.
• W2044777781 date "2009-02-22" @default.
• W2044777781 modified "2023-10-18" @default.
• W2044777781 title "Automated image-based phenotypic analysis in zebrafish embryos" @default.
• W2044777781 cites W1579189600 @default.
• W2044777781 cites W1966901116 @default.
• W2044777781 cites W1994279105 @default.
• W2044777781 cites W2001717001 @default.
• W2044777781 cites W2009766076 @default.
• W2044777781 cites W2010554563 @default.
• W2044777781 cites W2016046902 @default.
• W2044777781 cites W2022724803 @default.
• W2044777781 cites W2029284265 @default.
• W2044777781 cites W2034265209 @default.
• W2044777781 cites W2047642636 @default.
• W2044777781 cites W2050376918 @default.
• W2044777781 cites W2051732363 @default.
• W2044777781 cites W2081365810 @default.
• W2044777781 cites W2082472219 @default.
• W2044777781 cites W2082717309 @default.
• W2044777781 cites W2083740430 @default.
• W2044777781 cites W2091760375 @default.
• W2044777781 cites W2097449851 @default.
• W2044777781 cites W2099905447 @default.
• W2044777781 cites W2105772745 @default.
• W2044777781 cites W2123938765 @default.
• W2044777781 cites W2134634408 @default.
• W2044777781 cites W2143103411 @default.
• W2044777781 cites W2155966682 @default.
• W2044777781 cites W2162424885 @default.
• W2044777781 cites W2162585555 @default.
• W2044777781 doi "https://doi.org/10.1002/dvdy.21892" @default.
• W2044777781 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2861575" @default.
• W2044777781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19235725" @default.
• W2044777781 hasPublicationYear "2009" @default.
• W2044777781 type Work @default.
• W2044777781 sameAs 2044777781 @default.
• W2044777781 citedByCount "121" @default.
• W2044777781 countsByYear W20447777812012 @default.
• W2044777781 countsByYear W20447777812013 @default.
• W2044777781 countsByYear W20447777812014 @default.
• W2044777781 countsByYear W20447777812015 @default.
• W2044777781 countsByYear W20447777812016 @default.
• W2044777781 countsByYear W20447777812017 @default.
• W2044777781 countsByYear W20447777812018 @default.
• W2044777781 countsByYear W20447777812019 @default.
• W2044777781 countsByYear W20447777812020 @default.
• W2044777781 countsByYear W20447777812021 @default.
• W2044777781 countsByYear W20447777812022 @default.
• W2044777781 countsByYear W20447777812023 @default.
• W2044777781 crossrefType "journal-article" @default.
• W2044777781 hasAuthorship W2044777781A5018254555 @default.
• W2044777781 hasAuthorship W2044777781A5035575101 @default.
• W2044777781 hasAuthorship W2044777781A5038463777 @default.
• W2044777781 hasAuthorship W2044777781A5045341517 @default.
• W2044777781 hasAuthorship W2044777781A5059505159 @default.
• W2044777781 hasAuthorship W2044777781A5085858115 @default.
• W2044777781 hasAuthorship W2044777781A5087527556 @default.
• W2044777781 hasBestOaLocation W20447777811 @default.
• W2044777781 hasConcept C102230213 @default.
• W2044777781 hasConcept C104317684 @default.
• W2044777781 hasConcept C115901376 @default.
• W2044777781 hasConcept C127413603 @default.
• W2044777781 hasConcept C127716648 @default.
• W2044777781 hasConcept C1491633281 @default.
• W2044777781 hasConcept C154945302 @default.
• W2044777781 hasConcept C157044486 @default.
• W2044777781 hasConcept C196843134 @default.
• W2044777781 hasConcept C19843653 @default.
• W2044777781 hasConcept C2776878037 @default.
• W2044777781 hasConcept C41008148 @default.
• W2044777781 hasConcept C54355233 @default.
• W2044777781 hasConcept C70721500 @default.
• W2044777781 hasConcept C78519656 @default.
• W2044777781 hasConcept C86803240 @default.
• W2044777781 hasConcept C89600930 @default.
• W2044777781 hasConcept C95444343 @default.
• W2044777781 hasConceptScore W2044777781C102230213 @default.
• W2044777781 hasConceptScore W2044777781C104317684 @default.
• W2044777781 hasConceptScore W2044777781C115901376 @default.
• W2044777781 hasConceptScore W2044777781C127413603 @default.
• W2044777781 hasConceptScore W2044777781C127716648 @default.
• W2044777781 hasConceptScore W2044777781C1491633281 @default.
• W2044777781 hasConceptScore W2044777781C154945302 @default.
• W2044777781 hasConceptScore W2044777781C157044486 @default.
• W2044777781 hasConceptScore W2044777781C196843134 @default.
• W2044777781 hasConceptScore W2044777781C19843653 @default.
• W2044777781 hasConceptScore W2044777781C2776878037 @default.
• W2044777781 hasConceptScore W2044777781C41008148 @default.
• W2044777781 hasConceptScore W2044777781C54355233 @default.

• next