Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044780623> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2044780623 endingPage "246" @default.
- W2044780623 startingPage "II" @default.
- W2044780623 abstract "Solid organ donors often develop hypotension due to vasodilation, and recently we observed that a variety of vasodilatory states are characterized by vasopressin deficiency and hypersensitivity. Thus, we investigated the prevalence of vasopressin deficiency in hypotensive solid organ donors without clinical evidence of diabetes insipidus; we also investigated the vasopressor effect of vasopressin replacement in hypotensive donors.Fifty organ donors were evaluated for hemodynamic instability, (mean arterial pressure [MAP]</= 70 mm Hg despite the use of catecholamine vasopressors), and in those unstable donors who were not already receiving exogenous vasopressin, low-dose vasopressin was administered as a continuous infusion (0. 04 to 0.1 U/min). MAP, catecholamine requirements, serum vasopressin, and serum osmolality were obtained before and after vasopressin administration. Ten patients meeting the enrollment criteria received vasopressin and MAP increased from 72.2+/-3.5 to 89.8+/-4.2 mm Hg, (P<0.05), allowing for complete discontinuation of catecholamine pressors in 4 (40%) patients and a decrement in pressor dose in 4 (40%). Plasma vasopressin levels (2.9+/-0.8 pg/mL) were low for the degree of hypotension.Hemodynamically unstable organ donors without clinically apparent diabetes insipidus display a defect in the baroreflex-mediated secretion of vasopressin. In these patients, low-dose vasopressin significantly increases blood pressure with a pressor response sufficient to reduce catecholamine administration." @default.
- W2044780623 created "2016-06-24" @default.
- W2044780623 creator A5008145092 @default.
- W2044780623 creator A5011932512 @default.
- W2044780623 creator A5031191671 @default.
- W2044780623 creator A5054898557 @default.
- W2044780623 creator A5066324234 @default.
- W2044780623 creator A5066885783 @default.
- W2044780623 creator A5080446143 @default.
- W2044780623 creator A5085767079 @default.
- W2044780623 date "1999-11-09" @default.
- W2044780623 modified "2023-10-01" @default.
- W2044780623 title "Vasopressin Deficiency and Pressor Hypersensitivity In Hemodynamically Unstable Organ Donors" @default.
- W2044780623 cites W140300842 @default.
- W2044780623 cites W1988426740 @default.
- W2044780623 cites W1995608648 @default.
- W2044780623 cites W1996110514 @default.
- W2044780623 cites W1996751708 @default.
- W2044780623 cites W2004095374 @default.
- W2044780623 cites W2040515379 @default.
- W2044780623 cites W2062054105 @default.
- W2044780623 cites W2409547353 @default.
- W2044780623 cites W2472468353 @default.
- W2044780623 doi "https://doi.org/10.1161/01.cir.100.suppl_2.ii-244" @default.
- W2044780623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10567311" @default.
- W2044780623 hasPublicationYear "1999" @default.
- W2044780623 type Work @default.
- W2044780623 sameAs 2044780623 @default.
- W2044780623 citedByCount "83" @default.
- W2044780623 countsByYear W20447806232012 @default.
- W2044780623 countsByYear W20447806232013 @default.
- W2044780623 countsByYear W20447806232014 @default.
- W2044780623 countsByYear W20447806232015 @default.
- W2044780623 countsByYear W20447806232016 @default.
- W2044780623 countsByYear W20447806232017 @default.
- W2044780623 countsByYear W20447806232018 @default.
- W2044780623 countsByYear W20447806232019 @default.
- W2044780623 countsByYear W20447806232020 @default.
- W2044780623 countsByYear W20447806232021 @default.
- W2044780623 countsByYear W20447806232023 @default.
- W2044780623 crossrefType "journal-article" @default.
- W2044780623 hasAuthorship W2044780623A5008145092 @default.
- W2044780623 hasAuthorship W2044780623A5011932512 @default.
- W2044780623 hasAuthorship W2044780623A5031191671 @default.
- W2044780623 hasAuthorship W2044780623A5054898557 @default.
- W2044780623 hasAuthorship W2044780623A5066324234 @default.
- W2044780623 hasAuthorship W2044780623A5066885783 @default.
- W2044780623 hasAuthorship W2044780623A5080446143 @default.
- W2044780623 hasAuthorship W2044780623A5085767079 @default.
- W2044780623 hasConcept C120770815 @default.
- W2044780623 hasConcept C126322002 @default.
- W2044780623 hasConcept C134018914 @default.
- W2044780623 hasConcept C178853913 @default.
- W2044780623 hasConcept C2775894120 @default.
- W2044780623 hasConcept C2776370428 @default.
- W2044780623 hasConcept C2776958162 @default.
- W2044780623 hasConcept C42219234 @default.
- W2044780623 hasConcept C71924100 @default.
- W2044780623 hasConcept C84393581 @default.
- W2044780623 hasConceptScore W2044780623C120770815 @default.
- W2044780623 hasConceptScore W2044780623C126322002 @default.
- W2044780623 hasConceptScore W2044780623C134018914 @default.
- W2044780623 hasConceptScore W2044780623C178853913 @default.
- W2044780623 hasConceptScore W2044780623C2775894120 @default.
- W2044780623 hasConceptScore W2044780623C2776370428 @default.
- W2044780623 hasConceptScore W2044780623C2776958162 @default.
- W2044780623 hasConceptScore W2044780623C42219234 @default.
- W2044780623 hasConceptScore W2044780623C71924100 @default.
- W2044780623 hasConceptScore W2044780623C84393581 @default.
- W2044780623 hasIssue "Supplement 2" @default.
- W2044780623 hasLocation W20447806231 @default.
- W2044780623 hasLocation W20447806232 @default.
- W2044780623 hasOpenAccess W2044780623 @default.
- W2044780623 hasPrimaryLocation W20447806231 @default.
- W2044780623 hasRelatedWork W1983315707 @default.
- W2044780623 hasRelatedWork W1992645942 @default.
- W2044780623 hasRelatedWork W1993936129 @default.
- W2044780623 hasRelatedWork W2003587549 @default.
- W2044780623 hasRelatedWork W2019938707 @default.
- W2044780623 hasRelatedWork W2021993512 @default.
- W2044780623 hasRelatedWork W2033301635 @default.
- W2044780623 hasRelatedWork W2033746374 @default.
- W2044780623 hasRelatedWork W2072039282 @default.
- W2044780623 hasRelatedWork W2089540576 @default.
- W2044780623 hasVolume "100" @default.
- W2044780623 isParatext "false" @default.
- W2044780623 isRetracted "false" @default.
- W2044780623 magId "2044780623" @default.
- W2044780623 workType "article" @default.