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• W2044796416 abstract "Many fungal pathogens undergo morphological transformations during host invasion. However, the significance of this for fungal pathogenesis is not clear. Both yeast and hyphal cells have properties well suited to tissue invasion and evasion of the immune system. However, molecular control circuits that regulate morphogenesis also regulate the expression of other virulence traits. To establish the extent to which morphogenesis impacts on pathogenesis, it is necessary to characterise the morphology of the fungus at different stages and locations during the natural history of a disease and to untangle how gene expression is modulated at these stages. This review considers the role of morphogenesis in fungal infection and argues that no simple, universal relationship can be drawn between morphology and the invasive potential of a fungus." @default.
• W2044796416 created "2016-06-24" @default.
• W2044796416 creator A5019826825 @default.
• W2044796416 creator A5030174171 @default.
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• W2044796416 date "2002-08-01" @default.
• W2044796416 modified "2023-10-16" @default.
• W2044796416 title "Fungal morphogenesis and host invasion" @default.
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• W2044796416 doi "https://doi.org/10.1016/s1369-5274(02)00338-7" @default.
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• W2044796416 hasPublicationYear "2002" @default.
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