FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044806054> ?p ?o ?g. }

• W2044806054 endingPage "35" @default.
• W2044806054 startingPage "30" @default.
• W2044806054 abstract "The diagnosis of alcohol use disorder is based on clinical signs and on the measurement of biological markers. However, these markers are neither sufficiently sensitive, nor specific enough, for determining the effects of alcohol abuse on the central nervous system. Serum neurotrophins are important regulators of neural survival, development, function, and plasticity and have been found to be reduced in alcohol use disorder. The aim of this study was to investigate the alterations in serum neurotrophin levels (brain-derived neurotrophic factor [BDNF], glial-derived neurotrophic factor [GDNF], and nerve growth factor [NGF]) in alcohol use disorder in a young population, and thus possibly representing the early stages of the illness.This is a cross-sectional study, nested in a population-based study of people aged 18 to 35, involving 795 participants. The participants responded to the CAGE questionnaire, and a CAGE score of ≥2 was considered to be a positive screen for the abuse/dependence or moderate to severe alcohol use disorder. Serum BDNF, GDNF, and NGF levels were measured by ELISA.In the CAGE ≥ 2 group, GDNF (p ≤ 0.001) and NGF (p ≤ 0.001) serum levels were significantly increased, and the BDNF elevation was near a statistical significance (p = 0.068) when compared to the CAGE < 2 group. A significantly positive correlation was observed only in the CAGE ≥ 2 group for BDNF/GDNF (r = 0.37, p < 0.001) and GDNF/NGF (r = 0.84, p < 0.001) levels. The correlation between the NGF and BDNF levels was significantly positive in both groups (r = 0.28, p < 0.001 for the CAGE < 2 group, and r = 0.30, p = 0.008 for the CAGE ≥ 2 group).These results suggest that elevated neurotrophins are candidate markers for the early stages of alcohol misuse." @default.
• W2044806054 created "2016-06-24" @default.
• W2044806054 creator A5007720324 @default.
• W2044806054 creator A5010272459 @default.
• W2044806054 creator A5015814390 @default.
• W2044806054 creator A5029058192 @default.
• W2044806054 creator A5033453253 @default.
• W2044806054 creator A5037941430 @default.
• W2044806054 creator A5053545982 @default.
• W2044806054 creator A5056510807 @default.
• W2044806054 creator A5066093847 @default.
• W2044806054 creator A5073579926 @default.
• W2044806054 creator A5075176761 @default.
• W2044806054 creator A5091772753 @default.
• W2044806054 date "2015-01-01" @default.
• W2044806054 modified "2023-10-08" @default.
• W2044806054 title "Increased Serum Neurotrophin Levels Related to Alcohol Use Disorder in a Young Population Sample" @default.
• W2044806054 cites W1487219037 @default.
• W2044806054 cites W1579354630 @default.
• W2044806054 cites W1963964581 @default.
• W2044806054 cites W1968488639 @default.
• W2044806054 cites W1997906961 @default.
• W2044806054 cites W1997969083 @default.
• W2044806054 cites W2000455803 @default.
• W2044806054 cites W2002567659 @default.
• W2044806054 cites W2004320707 @default.
• W2044806054 cites W2004673401 @default.
• W2044806054 cites W2025113850 @default.
• W2044806054 cites W2036178921 @default.
• W2044806054 cites W2055390989 @default.
• W2044806054 cites W2073887203 @default.
• W2044806054 cites W2081296838 @default.
• W2044806054 cites W2081701770 @default.
• W2044806054 cites W2082995490 @default.
• W2044806054 cites W2087404902 @default.
• W2044806054 cites W2089753821 @default.
• W2044806054 cites W2090037933 @default.
• W2044806054 cites W2090065169 @default.
• W2044806054 cites W2090978979 @default.
• W2044806054 cites W2091128359 @default.
• W2044806054 cites W2095013890 @default.
• W2044806054 cites W2102240317 @default.
• W2044806054 cites W2114020311 @default.
• W2044806054 cites W2114457069 @default.
• W2044806054 cites W2119197433 @default.
• W2044806054 cites W2122026190 @default.
• W2044806054 cites W2148024819 @default.
• W2044806054 cites W2157619905 @default.
• W2044806054 cites W2162238265 @default.
• W2044806054 cites W2163712399 @default.
• W2044806054 cites W2163850423 @default.
• W2044806054 cites W4295925095 @default.
• W2044806054 doi "https://doi.org/10.1111/acer.12592" @default.
• W2044806054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25623403" @default.
• W2044806054 hasPublicationYear "2015" @default.
• W2044806054 type Work @default.
• W2044806054 sameAs 2044806054 @default.
• W2044806054 citedByCount "18" @default.
• W2044806054 countsByYear W20448060542015 @default.
• W2044806054 countsByYear W20448060542016 @default.
• W2044806054 countsByYear W20448060542017 @default.
• W2044806054 countsByYear W20448060542018 @default.
• W2044806054 countsByYear W20448060542019 @default.
• W2044806054 countsByYear W20448060542020 @default.
• W2044806054 countsByYear W20448060542022 @default.
• W2044806054 countsByYear W20448060542023 @default.
• W2044806054 crossrefType "journal-article" @default.
• W2044806054 hasAuthorship W2044806054A5007720324 @default.
• W2044806054 hasAuthorship W2044806054A5010272459 @default.
• W2044806054 hasAuthorship W2044806054A5015814390 @default.
• W2044806054 hasAuthorship W2044806054A5029058192 @default.
• W2044806054 hasAuthorship W2044806054A5033453253 @default.
• W2044806054 hasAuthorship W2044806054A5037941430 @default.
• W2044806054 hasAuthorship W2044806054A5053545982 @default.
• W2044806054 hasAuthorship W2044806054A5056510807 @default.
• W2044806054 hasAuthorship W2044806054A5066093847 @default.
• W2044806054 hasAuthorship W2044806054A5073579926 @default.
• W2044806054 hasAuthorship W2044806054A5075176761 @default.
• W2044806054 hasAuthorship W2044806054A5091772753 @default.
• W2044806054 hasConcept C118552586 @default.
• W2044806054 hasConcept C126322002 @default.
• W2044806054 hasConcept C134018914 @default.
• W2044806054 hasConcept C15744967 @default.
• W2044806054 hasConcept C160539049 @default.
• W2044806054 hasConcept C170493617 @default.
• W2044806054 hasConcept C185856081 @default.
• W2044806054 hasConcept C2778423431 @default.
• W2044806054 hasConcept C2778790584 @default.
• W2044806054 hasConcept C2780931562 @default.
• W2044806054 hasConcept C2908647359 @default.
• W2044806054 hasConcept C71924100 @default.
• W2044806054 hasConcept C92020748 @default.
• W2044806054 hasConcept C99454951 @default.
• W2044806054 hasConceptScore W2044806054C118552586 @default.
• W2044806054 hasConceptScore W2044806054C126322002 @default.
• W2044806054 hasConceptScore W2044806054C134018914 @default.
• W2044806054 hasConceptScore W2044806054C15744967 @default.
• W2044806054 hasConceptScore W2044806054C160539049 @default.

• next