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- W2044807798 abstract "A multi-spectral direct chromophore and scattering reconstruction for frequency domain NIR tomography has been implemented using constraints of the known molar spectra of the chromophores and a Mie theory approximation for scattering. This was tested in a tumor-simulating phantom containing an inclusion with higher hemoglobin, lower oxygenation and contrast in scatter. The recovered images were quantitatively accurate and showed substantial improvement over existing methods; and in addition, showed robust results tested for up to 5% noise in amplitude and phase measurements. When applied to a clinical subject with fibrocystic disease, the tumor was visible in hemoglobin and water, but no decrease in oxygenation was observed, making oxygen saturation, a potential diagnostic indicator." @default.
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- W2044807798 date "2005-04-28" @default.
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- W2044807798 title "Spectrally constrained NIR tomography for breast imaging: simulations and clinical results" @default.
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- W2044807798 doi "https://doi.org/10.1117/12.590576" @default.
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