Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044853430> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2044853430 abstract "Abstract Introduction The aim of this study was to determine the efficacy and safety of docetaxel-based systemic chemotherapy in elderly patients with castration-resistant prostate cancer (CRPC). Material and methods We retrospectively reviewed the clinical records of 36 patients with CRPC who were treated with docetaxel-based systemic chemotherapy at a single institution between May 2005 and April 2010. After screening, 30 patients met the eligibility criteria, and were included. Patients were placed into 2 groups: group 1 consisted of 9 patients aged Results The median age was 72 years, and the median performance status was 0. The median baseline prostate specific antigen (PSA) was 33.8 ng/mL. The mean number of docetaxel chemotherapy cycles was 5.8. The PSA response rate was 48.2%, and the measurable disease response rate was 15.0%, and these rates did not differ between the two groups. The median time to PSA progression and median overall survival were 6 and 9 months, respectively. Five patients experienced grade 3 or higher neutropenia. The drug-related toxicity was not different between the two groups. Conclusions The response of elderly CRPC patients with good performance status to docetaxel-based systemic chemotherapy was similar to that of younger patients. Docetaxel-based systemic chemotherapy is generally tolerated in elderly patients with good performance status." @default.
- W2044853430 created "2016-06-24" @default.
- W2044853430 creator A5058261863 @default.
- W2044853430 creator A5072044838 @default.
- W2044853430 creator A5084583632 @default.
- W2044853430 date "2012-07-01" @default.
- W2044853430 modified "2023-09-24" @default.
- W2044853430 title "Docetaxel-based systemic chemotherapy in elderly Korean men with castration-resistant prostate cancer" @default.
- W2044853430 cites W1984082819 @default.
- W2044853430 cites W2019598100 @default.
- W2044853430 cites W2048978380 @default.
- W2044853430 cites W2063935328 @default.
- W2044853430 cites W2077658945 @default.
- W2044853430 cites W2080439368 @default.
- W2044853430 cites W2088089080 @default.
- W2044853430 cites W2110188261 @default.
- W2044853430 cites W2120292596 @default.
- W2044853430 cites W2120619290 @default.
- W2044853430 cites W2127697086 @default.
- W2044853430 cites W2139248078 @default.
- W2044853430 cites W2156127723 @default.
- W2044853430 cites W2165269767 @default.
- W2044853430 cites W2165542862 @default.
- W2044853430 cites W3111081893 @default.
- W2044853430 doi "https://doi.org/10.1016/j.acuroe.2011.09.004" @default.
- W2044853430 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22386299" @default.
- W2044853430 hasPublicationYear "2012" @default.
- W2044853430 type Work @default.
- W2044853430 sameAs 2044853430 @default.
- W2044853430 citedByCount "3" @default.
- W2044853430 countsByYear W20448534302012 @default.
- W2044853430 crossrefType "journal-article" @default.
- W2044853430 hasAuthorship W2044853430A5058261863 @default.
- W2044853430 hasAuthorship W2044853430A5072044838 @default.
- W2044853430 hasAuthorship W2044853430A5084583632 @default.
- W2044853430 hasConcept C121608353 @default.
- W2044853430 hasConcept C126322002 @default.
- W2044853430 hasConcept C143998085 @default.
- W2044853430 hasConcept C2776694085 @default.
- W2044853430 hasConcept C2776907518 @default.
- W2044853430 hasConcept C2777063308 @default.
- W2044853430 hasConcept C2780192828 @default.
- W2044853430 hasConcept C2781190966 @default.
- W2044853430 hasConcept C2781406297 @default.
- W2044853430 hasConcept C71924100 @default.
- W2044853430 hasConceptScore W2044853430C121608353 @default.
- W2044853430 hasConceptScore W2044853430C126322002 @default.
- W2044853430 hasConceptScore W2044853430C143998085 @default.
- W2044853430 hasConceptScore W2044853430C2776694085 @default.
- W2044853430 hasConceptScore W2044853430C2776907518 @default.
- W2044853430 hasConceptScore W2044853430C2777063308 @default.
- W2044853430 hasConceptScore W2044853430C2780192828 @default.
- W2044853430 hasConceptScore W2044853430C2781190966 @default.
- W2044853430 hasConceptScore W2044853430C2781406297 @default.
- W2044853430 hasConceptScore W2044853430C71924100 @default.
- W2044853430 hasLocation W20448534301 @default.
- W2044853430 hasOpenAccess W2044853430 @default.
- W2044853430 hasPrimaryLocation W20448534301 @default.
- W2044853430 hasRelatedWork W1971749511 @default.
- W2044853430 hasRelatedWork W2010765098 @default.
- W2044853430 hasRelatedWork W2094570582 @default.
- W2044853430 hasRelatedWork W2194358893 @default.
- W2044853430 hasRelatedWork W2299690226 @default.
- W2044853430 hasRelatedWork W2355902919 @default.
- W2044853430 hasRelatedWork W2735900144 @default.
- W2044853430 hasRelatedWork W2770702948 @default.
- W2044853430 hasRelatedWork W3153927195 @default.
- W2044853430 hasRelatedWork W4226303148 @default.
- W2044853430 isParatext "false" @default.
- W2044853430 isRetracted "false" @default.
- W2044853430 magId "2044853430" @default.
- W2044853430 workType "article" @default.