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- W2044857546 abstract "Objective : To assess the efficacy and patients' tolerance of topical tacrolimus ointment for the treatment of atopic dermatitis in Chinese children during hot and humid seasons. Methods : Tacrolimus ointment at a concentration of 0.03% was applied for up to 4 weeks. Patients were assessed at weekly intervals for adverse events and efficacy. Results : Thirty‐four patients completed the study. Twenty‐seven percent of patients showed greater than 75% improvement according to the investigators' Global Evaluation of Clinical Response from Week 1 onward. The mean patients' assessment of treatment effects and Eczema Area Severity Index decreased by 60% after treatment for 4 weeks ( p <0.001), and the mean score for patients' assessment of pruritus decreased by 41% at Week 4 ( p <0.001). Pruritus and burning sensation were the two main adverse events reported. Conclusions : The short‐term monotherapy of childhood atopic dermatitis with tacrolimus ointment is well tolerated and effective during the hot and humid seasons in Hong Kong." @default.
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- W2044857546 date "2006-01-01" @default.
- W2044857546 modified "2023-10-16" @default.
- W2044857546 title "Efficacy and Safety of Tacrolimus Ointment Monotherapy in Chinese Children With Atopic Dermatitis" @default.
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- W2044857546 doi "https://doi.org/10.1111/j.1540-9740.2006.04249.x" @default.
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