FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044890639> ?p ?o ?g. }

• W2044890639 endingPage "1983" @default.
• W2044890639 startingPage "1977" @default.
• W2044890639 abstract "BACKGROUND The chronobiology of asthma suggests that, for once-daily dosing, an evening dose may be the most effective treatment paradigm. OBJECTIVE To evaluate the efficacy and safety of mometasone furoate dry powder inhaler (MF-DPI) administered once daily in the evening or twice daily in patients with asthma previously maintained on twice-daily regimens of inhaled corticosteroids. METHODS In this 12-week, multicenter, placebo-controlled trial, 268 subjects ≥12 years of age with inhaled corticosteroid–dependent asthma and baseline forced expiratory volume in 1 second (FEV 1 ) between 50% and 85% of predicted were randomized to receive treatment with MF-DPI 400 μg once daily in the evening, MF-DPI 200 μg twice daily, or placebo. The primary efficacy variable was mean change in FEV1 from baseline to endpoint. Other lung function measures, asthma symptoms, quality of life, and rescue medication use also were assessed. RESULTS At endpoint, mean FEV 1 was significantly improved with both MF-DPI doses compared with placebo (p < 0.001). The 2 active treatment groups were statistically indistinguishable from each other. Secondary efficacy variables, including nocturnal awakenings, asthma worsenings, quality of life, and rescue medication use, were also significantly improved for both MF-DPI treatments compared with placebo. Both dosages were well tolerated; no clinically meaningful changes in laboratory values or vital signs were observed. CONCLUSIONS MF-DPI 400 μg once daily in the evening was as effective as MF-DPI 200 μg twice daily in improving pulmonary function, asthma symptoms, and quality of life compared with placebo in subjects previously using twice-daily regimens of an inhaled corticosteroid." @default.
• W2044890639 created "2016-06-24" @default.
• W2044890639 creator A5044980958 @default.
• W2044890639 creator A5046991022 @default.
• W2044890639 creator A5067604175 @default.
• W2044890639 creator A5076347136 @default.
• W2044890639 creator A5082017061 @default.
• W2044890639 creator A5091200779 @default.
• W2044890639 date "2005-12-01" @default.
• W2044890639 modified "2023-10-04" @default.
• W2044890639 title "Effects of Mometasone Furoate Given Once Daily in the Evening on Lung Function and Symptom Control in Persistent Asthma" @default.
• W2044890639 cites W1990015539 @default.
• W2044890639 cites W1993452567 @default.
• W2044890639 cites W2028066161 @default.
• W2044890639 cites W2028762287 @default.
• W2044890639 cites W2032576980 @default.
• W2044890639 cites W2035105554 @default.
• W2044890639 cites W2042843674 @default.
• W2044890639 cites W2048185200 @default.
• W2044890639 cites W2070435356 @default.
• W2044890639 cites W2096404419 @default.
• W2044890639 cites W2150971973 @default.
• W2044890639 cites W2604596332 @default.
• W2044890639 cites W3189604683 @default.
• W2044890639 cites W4244925229 @default.
• W2044890639 cites W4255371791 @default.
• W2044890639 doi "https://doi.org/10.1345/aph.1g410" @default.
• W2044890639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16264062" @default.
• W2044890639 hasPublicationYear "2005" @default.
• W2044890639 type Work @default.
• W2044890639 sameAs 2044890639 @default.
• W2044890639 citedByCount "40" @default.
• W2044890639 countsByYear W20448906392013 @default.
• W2044890639 countsByYear W20448906392014 @default.
• W2044890639 countsByYear W20448906392015 @default.
• W2044890639 countsByYear W20448906392016 @default.
• W2044890639 countsByYear W20448906392019 @default.
• W2044890639 countsByYear W20448906392020 @default.
• W2044890639 countsByYear W20448906392021 @default.
• W2044890639 countsByYear W20448906392022 @default.
• W2044890639 crossrefType "journal-article" @default.
• W2044890639 hasAuthorship W2044890639A5044980958 @default.
• W2044890639 hasAuthorship W2044890639A5046991022 @default.
• W2044890639 hasAuthorship W2044890639A5067604175 @default.
• W2044890639 hasAuthorship W2044890639A5076347136 @default.
• W2044890639 hasAuthorship W2044890639A5082017061 @default.
• W2044890639 hasAuthorship W2044890639A5091200779 @default.
• W2044890639 hasConcept C121332964 @default.
• W2044890639 hasConcept C126322002 @default.
• W2044890639 hasConcept C1276947 @default.
• W2044890639 hasConcept C142724271 @default.
• W2044890639 hasConcept C168563851 @default.
• W2044890639 hasConcept C203092338 @default.
• W2044890639 hasConcept C204787440 @default.
• W2044890639 hasConcept C27081682 @default.
• W2044890639 hasConcept C2776042228 @default.
• W2044890639 hasConcept C2776476923 @default.
• W2044890639 hasConcept C2776804153 @default.
• W2044890639 hasConcept C2777419714 @default.
• W2044890639 hasConcept C2779028295 @default.
• W2044890639 hasConcept C2780261241 @default.
• W2044890639 hasConcept C2781348165 @default.
• W2044890639 hasConcept C42219234 @default.
• W2044890639 hasConcept C71924100 @default.
• W2044890639 hasConcept C75603125 @default.
• W2044890639 hasConceptScore W2044890639C121332964 @default.
• W2044890639 hasConceptScore W2044890639C126322002 @default.
• W2044890639 hasConceptScore W2044890639C1276947 @default.
• W2044890639 hasConceptScore W2044890639C142724271 @default.
• W2044890639 hasConceptScore W2044890639C168563851 @default.
• W2044890639 hasConceptScore W2044890639C203092338 @default.
• W2044890639 hasConceptScore W2044890639C204787440 @default.
• W2044890639 hasConceptScore W2044890639C27081682 @default.
• W2044890639 hasConceptScore W2044890639C2776042228 @default.
• W2044890639 hasConceptScore W2044890639C2776476923 @default.
• W2044890639 hasConceptScore W2044890639C2776804153 @default.
• W2044890639 hasConceptScore W2044890639C2777419714 @default.
• W2044890639 hasConceptScore W2044890639C2779028295 @default.
• W2044890639 hasConceptScore W2044890639C2780261241 @default.
• W2044890639 hasConceptScore W2044890639C2781348165 @default.
• W2044890639 hasConceptScore W2044890639C42219234 @default.
• W2044890639 hasConceptScore W2044890639C71924100 @default.
• W2044890639 hasConceptScore W2044890639C75603125 @default.
• W2044890639 hasIssue "12" @default.
• W2044890639 hasLocation W20448906391 @default.
• W2044890639 hasLocation W20448906392 @default.
• W2044890639 hasOpenAccess W2044890639 @default.
• W2044890639 hasPrimaryLocation W20448906391 @default.
• W2044890639 hasRelatedWork W2035127448 @default.
• W2044890639 hasRelatedWork W2036471103 @default.
• W2044890639 hasRelatedWork W2038508805 @default.
• W2044890639 hasRelatedWork W2135030290 @default.
• W2044890639 hasRelatedWork W2140441261 @default.
• W2044890639 hasRelatedWork W2147227209 @default.
• W2044890639 hasRelatedWork W2157512035 @default.
• W2044890639 hasRelatedWork W2396132629 @default.
• W2044890639 hasRelatedWork W3154998850 @default.
• W2044890639 hasRelatedWork W2183877426 @default.

• next