FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044918208> ?p ?o ?g. }

• W2044918208 endingPage "49" @default.
• W2044918208 startingPage "41" @default.
• W2044918208 abstract "SUMMARY Grapevine fanleaf virus (GFLV) is one of the most destructive pathogens of grapevine. In this study, we generated monoclonal antibodies binding specifically to the coat protein of GFLV. Antibody FL 3 , which bound most strongly to GFLV and showed cross‐reactivity to Arabis mosaic virus (ArMV), was used to construct the single‐chain antibody fragment scFvGFLVcp‐55. To evaluate the potential of this single‐chain variable fragment (scFv) to confer antibody‐mediated virus resistance, transgenic Nicotiana benthamiana plants were generated in which the scFv accumulated in the cytosol. Recombinant protein levels of up to 0.1% total soluble protein were achieved. The T 1 and T 2 progenies conferred partial or complete protection against GFLV on challenge with the viral pathogen. The resistance to GFLV in transgenic plants was strictly related to scFvGFLVcp‐55 accumulation levels, confirming that the antibody fragment was functional in planta and responsible for the GFLV resistance. In addition, transgenic plants conferring complete protection to GFLV showed substantially enhanced tolerance to ArMV. We demonstrate the first step towards the control of grapevine fanleaf degeneration, as scFvGFLVcp‐55 could be an ideal candidate for mediating nepovirus resistance." @default.
• W2044918208 created "2016-06-24" @default.
• W2044918208 creator A5004025915 @default.
• W2044918208 creator A5018739944 @default.
• W2044918208 creator A5036887130 @default.
• W2044918208 creator A5047164999 @default.
• W2044918208 creator A5049288387 @default.
• W2044918208 creator A5063258885 @default.
• W2044918208 date "2009-01-01" @default.
• W2044918208 modified "2023-09-26" @default.
• W2044918208 title "<i>Grapevine fanleaf virus</i>(GFLV)‐specific antibodies confer GFLV and<i>Arabis mosaic virus</i>(ArMV) resistance in<i>Nicotiana benthamiana</i>" @default.
• W2044918208 cites W121621337 @default.
• W2044918208 cites W1269723273 @default.
• W2044918208 cites W128305924 @default.
• W2044918208 cites W1596518357 @default.
• W2044918208 cites W1949110994 @default.
• W2044918208 cites W1978549702 @default.
• W2044918208 cites W1986104107 @default.
• W2044918208 cites W2007128923 @default.
• W2044918208 cites W2007885388 @default.
• W2044918208 cites W2009087758 @default.
• W2044918208 cites W2009834607 @default.
• W2044918208 cites W2010962189 @default.
• W2044918208 cites W2011321297 @default.
• W2044918208 cites W2020093424 @default.
• W2044918208 cites W2024635871 @default.
• W2044918208 cites W2028622989 @default.
• W2044918208 cites W2030522563 @default.
• W2044918208 cites W2040190421 @default.
• W2044918208 cites W2044967120 @default.
• W2044918208 cites W2060276508 @default.
• W2044918208 cites W2066537772 @default.
• W2044918208 cites W2067067694 @default.
• W2044918208 cites W2079739240 @default.
• W2044918208 cites W2087414852 @default.
• W2044918208 cites W2088163512 @default.
• W2044918208 cites W2099937013 @default.
• W2044918208 cites W2109975826 @default.
• W2044918208 cites W2119370926 @default.
• W2044918208 cites W2119589521 @default.
• W2044918208 cites W2120165772 @default.
• W2044918208 cites W2121666002 @default.
• W2044918208 cites W2149156187 @default.
• W2044918208 cites W2155246579 @default.
• W2044918208 cites W2164938305 @default.
• W2044918208 cites W2167897586 @default.
• W2044918208 cites W2320926004 @default.
• W2044918208 cites W304505273 @default.
• W2044918208 cites W4236140387 @default.
• W2044918208 cites W4316622878 @default.
• W2044918208 doi "https://doi.org/10.1111/j.1364-3703.2008.00510.x" @default.
• W2044918208 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6640260" @default.
• W2044918208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19161351" @default.
• W2044918208 hasPublicationYear "2009" @default.
• W2044918208 type Work @default.
• W2044918208 sameAs 2044918208 @default.
• W2044918208 citedByCount "32" @default.
• W2044918208 countsByYear W20449182082012 @default.
• W2044918208 countsByYear W20449182082013 @default.
• W2044918208 countsByYear W20449182082014 @default.
• W2044918208 countsByYear W20449182082015 @default.
• W2044918208 countsByYear W20449182082016 @default.
• W2044918208 countsByYear W20449182082017 @default.
• W2044918208 countsByYear W20449182082018 @default.
• W2044918208 countsByYear W20449182082019 @default.
• W2044918208 countsByYear W20449182082021 @default.
• W2044918208 countsByYear W20449182082022 @default.
• W2044918208 crossrefType "journal-article" @default.
• W2044918208 hasAuthorship W2044918208A5004025915 @default.
• W2044918208 hasAuthorship W2044918208A5018739944 @default.
• W2044918208 hasAuthorship W2044918208A5036887130 @default.
• W2044918208 hasAuthorship W2044918208A5047164999 @default.
• W2044918208 hasAuthorship W2044918208A5049288387 @default.
• W2044918208 hasAuthorship W2044918208A5063258885 @default.
• W2044918208 hasBestOaLocation W20449182081 @default.
• W2044918208 hasConcept C104317684 @default.
• W2044918208 hasConcept C109110057 @default.
• W2044918208 hasConcept C159047783 @default.
• W2044918208 hasConcept C2522874641 @default.
• W2044918208 hasConcept C2776994594 @default.
• W2044918208 hasConcept C2780292513 @default.
• W2044918208 hasConcept C2780562374 @default.
• W2044918208 hasConcept C2994092193 @default.
• W2044918208 hasConcept C54355233 @default.
• W2044918208 hasConcept C67705224 @default.
• W2044918208 hasConcept C86803240 @default.
• W2044918208 hasConceptScore W2044918208C104317684 @default.
• W2044918208 hasConceptScore W2044918208C109110057 @default.
• W2044918208 hasConceptScore W2044918208C159047783 @default.
• W2044918208 hasConceptScore W2044918208C2522874641 @default.
• W2044918208 hasConceptScore W2044918208C2776994594 @default.
• W2044918208 hasConceptScore W2044918208C2780292513 @default.
• W2044918208 hasConceptScore W2044918208C2780562374 @default.
• W2044918208 hasConceptScore W2044918208C2994092193 @default.
• W2044918208 hasConceptScore W2044918208C54355233 @default.
• W2044918208 hasConceptScore W2044918208C67705224 @default.
• W2044918208 hasConceptScore W2044918208C86803240 @default.
• W2044918208 hasIssue "1" @default.

• next